Mariana Vargas Cruz

ORCID: 0000-0001-8569-2234
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About
Contact & Profiles
Research Areas
  • Genetic diversity and population structure
  • Coastal wetland ecosystem dynamics
  • Marine and coastal plant biology
  • Plant and Fungal Species Descriptions
  • Plant Water Relations and Carbon Dynamics
  • Plant Pathogens and Fungal Diseases
  • Plant responses to elevated CO2
  • Plant and animal studies
  • Plant Molecular Biology Research
  • Medical Imaging and Pathology Studies
  • Photosynthetic Processes and Mechanisms
  • Fern and Epiphyte Biology
  • Fibroblast Growth Factor Research
  • Oil Palm Production and Sustainability
  • Ethnobotanical and Medicinal Plants Studies
  • Salivary Gland Tumors Diagnosis and Treatment
  • Identification and Quantification in Food
  • Oral and Maxillofacial Pathology
  • Tuberculosis Research and Epidemiology
  • Molecular Biology Techniques and Applications
  • RNA modifications and cancer
  • Genomics and Phylogenetic Studies
  • Environmental DNA in Biodiversity Studies
  • Infectious Diseases and Mycology
  • Cancer Genomics and Diagnostics

Hospital Sírio-Libanês
2023-2024

Universidade Estadual de Campinas (UNICAMP)
2016-2024

Universidade Federal de Minas Gerais
2012-2022

Abstract The Cerrado, the largest Neotropical savanna, and Brazilian Atlantic Forest form large ecotonal areas where savanna forest habitats occupy adjacent patches with closely related species occurring side by side, providing opportunities for hybridization. Here, we investigated evolutionary divergence between ecotypes of widely distributed tree Plathymenia reticulata ( n = 233 individuals). Genetic structure analysis P . was congruent recognition two ecotypes, whose captured proportion...

10.1002/ece3.8540 article EN cc-by Ecology and Evolution 2022-01-01

Abstract Local adaptation is often a product of environmental variations in geographical space and has implications for biodiversity conservation. We investigated the role latitudinal heterogeneity climate on organization genetic phenotypic variation dominant coastal tree Avicennia schaueriana . In common garden experiment, samples from an equatorial region, with pronounced seasonality precipitation, accumulated less biomass, showed lower stomatal conductance transpiration, narrower xylem...

10.1038/s41598-019-56469-w article EN cc-by Scientific Reports 2019-12-27

Environmental variation along the geographical space can shape populations by natural selection. In context of global warming and changing precipitation regimes, it is crucial to understand role environmental heterogeneity in tropical trees adaptation, given their disproportional contribution water carbon biogeochemical cycles. Here, we investigated how freshwater availability wetlands has influenced molecular variations black mangrove (Avicennia germinans). A total 57 were sampled at seven...

10.1111/mec.15330 article EN Molecular Ecology 2019-12-13

The goal of this research was to generate networks co-expressed genes explore the genomic responses Rhizophora mangle L. populations contrasting environments and use gene network analysis investigate their capacity for adaptation in face historical future perturbations climatic changes. RNA sequencing data were generated R. samples collected under field conditions from climate zones equatorial subtropical regions Brazil. A co-expression constructed using Pearson's correlation coefficient,...

10.3389/fpls.2018.01376 article EN cc-by Frontiers in Plant Science 2018-09-19

Abstract Assessing the relative importance of geographical and environmental factors to spatial distribution genetic variation can provide information about processes that maintain in natural populations. With a globally wide but very restricted habitat distribution, mangrove trees are useful model for studies aiming understand contributions these factors. Mangroves occur along continent–ocean interface tropical subtropical latitudes, regions considered inhospitable many other types plants....

10.1093/biolinnean/blaa199 article EN Biological Journal of the Linnean Society 2020-11-11

Twenty-seven nuclear microsatellite markers were developed for the mangrove fern, Acrostichum aureum (Pteridaceae), to investigate genetic structure and demographic history of only pantropical plant.Fifty-six A. individuals from three populations sampled genotyped characterize 27 loci. The number alleles expected heterozygosity ranged one 15 0.000 0.893, respectively. Across 26 polymorphic loci, Malaysian population showed much higher levels polymorphism compared other two in Guam Brazil....

10.3732/apps.1600042 article EN cc-by-nc Applications in Plant Sciences 2016-09-01

Microsatellite loci were isolated and characterized for use in population genetic studies of Plathymenia reticulata (Fabaceae), a tropical tree widespread the Atlantic Forest cerrado biomes South America.Nine microsatellite markers developed using simple sequence repeat-enriched library. Polymorphism was analyzed 51 individuals from two populations. All polymorphic, with number alleles per ranging five to 15 (mean alleles: 10.22). Observed expected heterozygosities ranged 0.313 1.000 0.280...

10.3732/ajb.1100511 article EN American Journal of Botany 2012-04-28

Abstract Local adaptation is often a product of environmental variations in the geographical space and has implications for biodiversity conservation. We investigated role latitudinal heterogeneity climate on organization genetic phenotypic variation dominant coastal tree, Avicennia schaueriana . In common garden experiment, samples from an equatorial region, marked by rainy/dry seasons, accumulated less biomass, showed lower stomatal conductance transpiration, narrower xylem vessels,...

10.1101/378612 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2018-07-27

ABSTRACT Mangroves are coastal ecosystems of great socioenvironmental importance that highly threatened by human activities. Mangrove trees live under harsh environmental conditions, which makes them sensitive to extreme weather events, particularly freezing events. Such events unpredictable and have catastrophic consequences for mangrove trees; therefore, understanding anticipating the impacts such essential directing future mitigation measures. Freezing cold currently limits distribution...

10.1101/2024.02.08.579386 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-02-12

ABSTRACT Assessing the relative importance of geographical and environmental factors to spatial distribution genetic variation can provide information about processes that maintain in natural populations. With a globally wide but very restricted habitat distribution, mangrove trees are useful model for studies aiming understand contributions these factors. Mangroves occur along continent–ocean interface tropical subtropical latitudes, regions considered inhospitable many other types plants....

10.1101/2020.01.08.889717 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-01-09

Oral cancer is the seventh most frequent type in our population and approximately 90% of these malignancies are squamous cell carcinoma. Genetic alterations tumor suppressor genes increase risk development, since associated with cycle control. Epigenetic changes involving regulatory related to initiation progression various tumors. The hyper methylation gene p16 found many types cancers silencing. aim this study was determine promoter region samples normal oral mucosa from patients technique...

10.5008/1809.7367.044 article EN Revista Científica Faesa 2011-06-01

Genomic profiling using next-generation sequencing (NGS) is fundamental for driving prognostic and therapy in cancer. Formalin-fixed paraffin embedded (FFPE) tissue the widely used material, whereas non-FFPE may represent an alternative. However, studies comparing NGS performance of materials to FFPE are still lacking literature. The objective this study was characterize preparations nucleic acid yield on both a capture-based amplicon-based platform. quality metrics obtained from were compared FFPE.

10.1002/dc.25267 article EN Diagnostic Cytopathology 2023-12-20

Abstract Environmental variation along the geographical space can shape populations by natural selection. In context of global warming, accompanied substantial changes in precipitation regimes, it is crucial to understand role environmental heterogeneity tropical trees adaptation, given their disproportional contribution water and carbon biogeochemical cycles. Here we investigated how freshwater availability wetlands has influenced molecular variations Black-Mangrove ( Avicennia germinans )....

10.1101/731760 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2019-08-10

Abstract Geographic and environmental differences have been identified as factors influencing Brazilian mangrove trees’ genetic diversity. Geographically, distinct species convergent spatial structures, indicating a limited gene flow between northern southern populations. Environmentally, genomic studies common garden experiments found evidence of local adaptations along the latitudinal gradient coast. However, little is known about how such adaptive heterogeneity could be affected by...

10.1101/2022.02.11.480143 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-02-14

Geographic and environmental differences have been identified as factors influencing Brazilian mangrove trees' genetic diversity. Geographically, distinct species convergent spatial structures, indicating a limited gene flow between northern southern populations. Environmentally, genomic studies common garden experiments found evidence of local adaptations along the latitudinal gradient coast. However, little is known about how such adaptive heterogeneity could be affected by rapidly...

10.3389/fcosc.2022.763325 article EN cc-by Frontiers in Conservation Science 2022-03-22
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