Zhenhua Shang

ORCID: 0000-0001-8570-7096
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Synthesis and biological activity
  • Oxidative Organic Chemistry Reactions
  • Synthesis and Biological Evaluation
  • Protein purification and stability
  • Catalytic C–H Functionalization Methods
  • Crystal structures of chemical compounds
  • Synthesis and Catalytic Reactions
  • Analytical Chemistry and Chromatography
  • Quinazolinone synthesis and applications
  • Urinary Bladder and Prostate Research
  • Biopolymer Synthesis and Applications
  • Cancer, Lipids, and Metabolism
  • Genetic and phenotypic traits in livestock
  • Structural and Chemical Analysis of Organic and Inorganic Compounds
  • Multicomponent Synthesis of Heterocycles
  • Cancer-related molecular mechanisms research
  • Bladder and Urothelial Cancer Treatments
  • Synthesis and Characterization of Heterocyclic Compounds
  • Inflammatory Biomarkers in Disease Prognosis
  • Genetic Mapping and Diversity in Plants and Animals
  • Circular RNAs in diseases
  • Bat Biology and Ecology Studies
  • Microfluidic and Capillary Electrophoresis Applications

Tianjin University
2004-2025

Geological Exploration Institute of Shandong Zhengyuan
2024-2025

Ministry of Natural Resources
2025

Hebei University of Science and Technology
2006-2024

Capital Medical University
2018-2024

Northwestern University
2024

Hebei Chemical and Pharmaceutical College
2012-2024

Chongqing Technology and Business University
2024

Hebei University of Engineering
2024

Xuan Wu Hospital of the Capital Medical University
2023

Yaks are a multifunctional and dominant livestock species on the Qinghai-Tibetan plateau. The yak grazing system is traditional transhumance system. Research focussed both understanding improving Development of local economies use new knowledge from research modern technology However, plateau ecosystem becoming dysfunctional through adverse climate sequences, over-population over-grazing. Chinese Government has implemented regional projects to address these degradation problems. Several...

10.1071/rj08012 article EN The Rangeland Journal 2008-01-01

Chemotherapy is the main treatment for bladder cancer, but drug resistance and side effects limit its application therapeutic effect. Herein, we constructed doxorubicin (DOX)/COOH-mesoporous silica nanoparticle/polyethylenimine (PEI)/nucleic acid chimeras (DOX/MSN/Chimeras) to reduce toxicity of chemotherapy drugs cancer cells. Transmission electron microscopy showed that PEI was coated on DOX/MSN/BSA nanoparticles with a diameter about 150 nm. DOX/MSN/PEI could control DOX release over 48...

10.1016/j.biopha.2024.117185 article EN Biomedicine & Pharmacotherapy 2024-07-24

ADVERTISEMENT RETURN TO ISSUEPREVNotePreparation of Cross-Linked Polystyrene Hollow Nanospheres via Surface-Initiated Atom Transfer Radical PolymerizationsG. D. Fu, Zhenhua Shang, Liang Hong, E. T. Kang, and K. G. NeohView Author Information Department Chemical & Biomolecular Engineering, National University Singapore, Kent Ridge, Singapore 119260 Cite this: Macromolecules 2005, 38, 18, 7867–7871Publication Date (Web):August 9, 2005Publication History Received30 April 2005Revised3 July...

10.1021/ma0509098 article EN Macromolecules 2005-08-09

Abstract The reaction of diorganyl disulfides or diselenides with PhICl 2 in DMF at room temperature led to the situ formation reactive organosulfenyl chloride (RSCl) selenenyl (ArSeCl), which reacted enaminone compounds afford a series α ‐thioenaminones ‐selenylenaminones, respectively, including bioactive inhibitor for Cdc25B and its analogue, via intermolecular oxidative C (sp )‐S/Se cross coupling reactions under metal‐free conditions. magnified image

10.1002/adsc.201900940 article EN Advanced Synthesis & Catalysis 2019-09-04

10.1109/icassp49660.2025.10888026 article EN ICASSP 2022 - 2022 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP) 2025-03-12

In deep and ultradeep well drilling operations, the coolant flow of drill bit directly impacts life efficiency. To improve service impregnated diamond bits reduce abnormal wear, this study employs numerical simulations process, incorporating thermal-fluid-mechanical coupling, to analyze field, pressure, temperature distribution on lip body. By optimizing design bit's waterway using different materials, influence offset angle efficiency cooling performance is validated through field tests....

10.1021/acsomega.4c11577 article EN cc-by-nc-nd ACS Omega 2025-03-18

Bckground: Emergence and the rising prevalence of extended-spectrum β-lactamases (ESBLs) producing multidrug-resistant Klebsiella spp. is a global concern. Methods: 391 samples were collected from environmental people in an intensive vegetable cultivation area eastern China June 2019. ESBLs-producing obtained by PCR strain identification. The resistance genotype phenotype determined drug susceptibility test. number size plasmids pulsed-field gel electrophoresis assays plasmids. plasmid...

10.1089/mdr.2024.0140 article EN Microbial Drug Resistance 2025-04-14

Nanoporous fluoropolymer films with dielectric constants below 2 are prepared via consecutive surface-initiated atom transfer radical polymerizations of pentafluorostyrene (PFS) and divinylbenzene (DVB) on silica nanospheres. After agglomeration the nanospheres, crosslinking nanospheres by UV, removal cores (see Figure), a nanoporous film constant as low 1.7 is formed.

10.1002/adma.200500762 article EN Advanced Materials 2005-09-15

Rapid and high-resolution imaging of large tissues is essential in biological research, like brain neuron connectivity research cancer margins imaging. Here a novel stage-scanning confocal microscopy was developed for rapid tissues. Line scanning methods strip strategy were used to increase the speed. The scientific CMOS as line detector sub-array mode optical sectioning ability can be easily adjusted by changing number detectors according different samples. Fluorescent beads showed...

10.1364/boe.6.001867 article EN cc-by Biomedical Optics Express 2015-04-23

This study aimed to investigate the associations between preoperative prognostic nutritional index (PNI), systemic immune-inflammation (SII) and overall survival (OS) cancer-specific (CSS) in high-risk non-muscle-invasive bladder cancer (NMIBC) patients who received intravesical instillation of Bacillus Calmette-Guerin (BCG) after transurethral resection tumour (TURBT).We retrospectively collected data from 387 NMIBC January 2004 December 2014. PNI was calculated as total lymphocyte count...

10.2147/cmar.s259117 article EN cc-by-nc Cancer Management and Research 2020-10-01

10.1016/0021-9673(94)00725-x article EN Journal of Chromatography A 1994-11-01

Abstract Gypenosides (GPs) have been reported to neuroprotective effects in addition other bioactivities. The protective activity of GPs during stroke and their on neural stem cells (NSCs) the ischemic brain not fully elucidated. Here, we test NSCs within subventricular zone (SVZ) middle cerebral artery occlusion (MCAO) rats. Our results show that pre‐treatment with can reduce infarct volume improve motor function following MCAO. Pre‐treatment significantly increased number BrdU‐positive...

10.1016/j.ijdevneu.2013.12.001 article EN International Journal of Developmental Neuroscience 2013-12-12

10.1016/s0021-9673(99)01147-4 article EN Journal of Chromatography A 2000-01-01
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