A5015055609- Advanced X-ray Imaging Techniques
- Advanced Electron Microscopy Techniques and Applications
- X-ray Spectroscopy and Fluorescence Analysis
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Laser-Plasma Interactions and Diagnostics
- Laser Design and Applications
- Optical Coatings and Gratings
- Advanced Fluorescence Microscopy Techniques
- Electromagnetic Simulation and Numerical Methods
- Geothermal Energy Systems and Applications
- Laser-induced spectroscopy and plasma
- Advanced Numerical Methods in Computational Mathematics
- Amoebic Infections and Treatments
- Climate change and permafrost
KTH Royal Institute of Technology
2011-2015
We present a laser plasma based x-ray microscope for the water window employing high-average power system generation. At 90 W brightness of 7.4 x 10(11) photons/(s sr μm(2)) was measured nitrogen Lyα line emission at 2.478 nm. Using multilayer condenser mirror with 0.3 % reflectivity 10(6) photons/(μm(2) s) were obtained in object plane. Microscopy performed 60 resolves 40 nm lines an exposure time s. The can be further reduced to 20 s by use new optics and operating its full 130 W.
Laboratory water window cryomicroscopy has recently demonstrated similar image quality as synchrotron-based microscopy but still with much longer exposure times, prohibiting the spread to a wider scientific community. Here we demonstrate high-resolution laboratory imaging of cryofrozen cells 10 s range times. The major improvement is operation λ=2.48 nm, 2 kHz liquid nitrogen jet laser plasma source high spatial and temporal stability at average brightness >1.5×1012 ph/(s×sr×μm2×line), i.e.,...
Tomographic reconstruction in soft x-ray microscopy is a powerful technique for obtaining high-resolution 3D images of biological samples. However, the depth focus such zone-plate-based microscopes typically shorter than thickness many relevant objects, challenging validity projection assumption used conventional algorithms. In order to make full use microscopes' high resolution, tomographic needs take into account. Here we present method achieve resolution sample when short compared...
In water-window soft x-ray microscopy the studied object is typically larger than depth of focus and sample illumination often partially coherent. This blurs out-of-focus features may introduce considerable fringing. Understanding influence these phenomena on image formation therefore important when interpreting experimental data. Here we present a wave-propagation model operating in 3D for simulating thick objects coherent microscopes. The compared with simulation methods as well...
Microscopic jets of cryogenic substances such as liquid nitrogen are important regenerative high-density targets for high-repetition rate, high-brightness laser-plasma soft x-ray sources. When operated in vacuum exhibit several non-classical instabilities that negatively influence the source's spatial and temporal stability, yield, brightness, parameters all applications water-window microscopy. In present paper, we investigate liquid-nitrogen with a flash-illumination imaging system allows...
In this paper the latest efforts to improve our nanofabrication process for soft x‐ray zone plates is presented. The resolving power, which proportional smallest outermost width of plate, increased by introducing cold development electron beam resist that used patterning. With we have fabricated Ni with 13‐nm and shown potential making 11‐nm half‐pitch lines in resist. Maintaining diffraction efficiency plate a great concern when decreased. To resolve problem developed so‐called Ni‐Ge build...
X‐ray wavefront propagation is a powerful technique when simulating the performance of x‐ray optical components. Using various numerical methods, interesting parameters such as focusing capability and efficiency can be investigated. Here we present toolbox DiffractX, implemented in MATLAB. It contains many different wave methods for simulation diffractive optics, including Fresnel propagation, finite difference method (FDM), thin object approximation, rigorous coupled theory (RCWT), element...