A5040896602- Adenosine and Purinergic Signaling
- Neuroscience of respiration and sleep
- Protein Hydrolysis and Bioactive Peptides
- Meat and Animal Product Quality
- Trypanosoma species research and implications
- Nanoplatforms for cancer theranostics
- Research on Leishmaniasis Studies
- Adolescent and Pediatric Healthcare
- Calcium signaling and nucleotide metabolism
- Ion-surface interactions and analysis
- Luminescence Properties of Advanced Materials
- Reproductive System and Pregnancy
- Photodynamic Therapy Research Studies
- Neuropeptides and Animal Physiology
- Problem and Project Based Learning
- Luminescence and Fluorescent Materials
- Microbial Inactivation Methods
- Viral Infections and Immunology Research
- Diamond and Carbon-based Materials Research
- Neurological Complications and Syndromes
- Pharmacological Receptor Mechanisms and Effects
- Pregnancy and Medication Impact
- Pneumocystis jirovecii pneumonia detection and treatment
- Science and Education Research
- Biochemical and Molecular Research
Rio de Janeiro Federal Institute of Education, Science and Technology
2015-2022
Fundação Oswaldo Cruz
2004-2022
Universidade Federal do Rio de Janeiro
1997-2008
Instituto de Biofísica Carlos Chagas Filho
2002
Macrophages and thymocytes express P 2Z /P2X 7 nucleotide receptors that bind extracellular ATP. These play a role in immune development control of microbial infections, but their presence on dendritic cells has not been reported. We investigated whether ATP could trigger receptor-dependent apoptosis cells. Apoptosis be selectively triggered by tetrabasic ATP, since other purine/pyrimidine nucleotides were ineffective, it was mimicked the receptor agonist, benzoylbenzoyl blocked magnesium...
Gap junctions are connexin-formed channels that play an important role in intercellular communication most cell types. In the immune system, specifically macrophages, expression of connexins and establishment functional gap still controversial issues. Macrophages express P2X7 receptors that, once activated by binding extracellular ATP, lead to opening transmembrane pores permeable molecules up 900 Da. There is evidence suggesting interplay between P2 different systems. Thus, we used...
Summary. CD8 + T lymphocytes are considered an important cell population involved in the control of parasitaemia and mortality after Trypanosoma cruzi infection. However, despite recent developments this field, mechanism whereby is exerted still not completely understood. Here we have used perforin knockout (–/–) mice infected with Y strain T. order to evaluate specifically participation perforin‐based cytotoxic pathway destruction cardiomyocytes, cellular inflammatory infiltration,...
Immunology is a knowledge area of paramount importance in life sciences and health care professional education with diverse applications, as well for general public understanding issues related to vaccination. However, many concepts are complex difficult understand based only on conventional classes or static images. The use tools, such educational software, may enhance the learning dynamic molecular phenomena that occur our bodies. Virtual software aims facilitate certain immunology...
The development of X-ray-absorbing scintillating nanoparticles is high interest for solving the short penetration depth problem visible and infrared light in photodynamic therapy (PDT). Thus, these are considered a promising treatment several types cancer. Herein, gadolinium oxide doped with europium ions (Gd2O3:Eu3+) were obtained by using polyvinyl alcohol as capping agent. Hybrid silica decorated europium-doped (SiO2-Gd2O3:Eu3+) also prepared through impregnation method. synthesized...