A5034063747- RNA Research and Splicing
- Genomics and Chromatin Dynamics
- Medical Imaging Techniques and Applications
- Single-cell and spatial transcriptomics
- Epigenetics and DNA Methylation
University of Cincinnati Medical Center
2022-2023
University of Cincinnati
2022
Transcription factors read the genome, fundamentally connecting DNA sequence to gene expression across diverse cell types. Determining how, where, and when TFs bind chromatin will advance our understanding of regulatory networks cellular behavior. The 2017 ENCODE-DREAM in vivo Transcription-Factor Binding Site ( TFBS ) Prediction Challenge highlighted value accessibility data prediction, establishing state-of-the-art methods for prediction from DNase-seq. However, more recent...
Abstract Transcription factors read the genome, fundamentally connecting DNA sequence to gene expression across diverse cell types. Determining how, where, and when TFs bind chromatin will advance our understanding of regulatory networks cellular behavior. The 2017 ENCODE-DREAM in vivo Transcription-Factor Binding Site ( TFBS ) Prediction Challenge highlighted value accessibility data prediction, establishing state-of-the- art methods for prediction from DNase-seq. However, more recent...