A5112260601- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- Breast Cancer Treatment Studies
- Radiation Therapy and Dosimetry
- Radiation Dose and Imaging
- Management of metastatic bone disease
- Radiomics and Machine Learning in Medical Imaging
- Advances in Oncology and Radiotherapy
- Digital Radiography and Breast Imaging
- Atomic and Subatomic Physics Research
- Cardiac Arrhythmias and Treatments
- Hemodynamic Monitoring and Therapy
- Cardiac pacing and defibrillation studies
- Advanced X-ray and CT Imaging
- Lung Cancer Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Body Composition Measurement Techniques
- Medical Imaging and Analysis
- Electrical and Bioimpedance Tomography
- Cardiovascular Function and Risk Factors
Central Finland Health Care District
2017-2025
Kuopio University Hospital
2011-2021
University of Eastern Finland
2014-2015
The spine shortens during the day because of compression intervertebral discs, causing problems in field localisation craniospinal irradiation. This study quantified effect treatment fraction timing on spinal length 13 patients. deviation distance from base skull to third lumbar vertebra setup images compared planning computed tomography image was determined. time between and imaging session registered. A decrease 0.8+/-0.2 mm/hour observed. As conclusion, we recommend fractions within two...
The spine shortens during the day because of gravity. This study quantified effect treatment fraction timing on spinal length in 13 craniospinal irradiation patients. distance deviation from base skull to third lumbar vertebra daily planar kilovoltage setup images compared planning computed tomography image was determined. time between and registered. A decrease 0.8±0.2 mm/hour observed. Timing fractions within two hours imaging session is advisable minimise potential dosimetric impact...
Respiratory motion may degrade image quality in cardiac PET imaging. Since studies often involve gating by ECG, a separate respiratory monitoring system is required increasing the logistic complexity of examination, case also needed. Thus, we investigated simultaneous acquisition both and signals using II limb lead mimicking electrode configuration during scans 11 patients. In addition to conventional static ECG-gated images, bioimpedance technique was utilized generate respiratory-...
This study aimed to determine the geometrical uncertainty of position heart with daily cone beam computed tomography (CBCT) during deep-inspiration breath-hold (DIBH) treatment left breast.A visually guided optical respiratory monitoring system was used in DIBH 15 breast cancer patients. Heart determined relation planning target volume (PTV) 225 fractions which low-dose CBCT images were compared CT images. In addition, lung apex and diaphragm measured evaluate success DIBH.The median shift 1...
Background. Respiratory motion in positron emission tomography/computed tomography (PET/CT) causes underestimation of standardized uptake value (SUV) and variation lesion volume, while PET CT attenuation correction (CTAC) mismatch may introduce artefacts. The aim was to compare end-expiratory gating methods CTAC.Material methods. Three named the minimum-constant, slope-based amplitude-median were developed evaluated on efficiency. Method evaluation optimization performed 23 simulated...
Setup errors are an important factor in the dosimetric accuracy of radiotherapy delivery. In this study, we investigated how rotational setup influence dose distribution volumetric modulated arc therapy (VMAT) and tangential field-in-field (FiF) treatment left-sided breast cancer with supraclavicular lymph node involvement deep inspiration breath hold. Treatment planning computed tomography images plans 20 patients were collected retrospectively for study. Rotational up to 3° simulated by...
Abstract Purpose In craniospinal irradiation, two or three isocenter groups along the craniocaudal axis are required to cover long treatment target. Adapting distance according daily deviations in patient position is challenging because dosimetric hot cold spots may occur field junction. The aim of this study was quantify effect adapting on dose distribution overlap region irradiation using partial‐arc volumetric modulated arc therapy. Methods magnitude direction quantified by registering...
The interplay effect of respiratory motion on the planned dose in free-breathing right-sided whole-breast irradiation (WBI) were studied by simulating hypofractionated VMAT treatment courses.Ten patients with phase-triggered 4D-CT images included study. plans targeting right breast created retrospectively moderately (40.05 Gy 15 fractions 2.67 Gy) and ultra-hypofractionated (26 5 5.2 schemes. 3D-CRT generated as a reference. All divided into phase-specific calculated corresponding phase...
Correction for respiratory motion in myocardial perfusion imaging requires sorting of emission data into windows where the intra-window is assumed to be negligible. However, it unclear how much acceptable. The aim this study was determine an optimal value residual motion. A custom-designed cardiac phantom created and imaged with a standard dual-detector SPECT/CT system using Tc-99m as radionuclide. Projection images were generated from list-mode simulating blur several magnitudes 0...
Abstract Background In ordered subsets expectation maximization (OSEM) reconstruction of electrocardiography (ECG)-gated myocardial perfusion single-photon emission computed tomography (SPECT), it is often assumed that the image acquisition time constant for each projection angle and ECG bin. Due to heart rate variability (HRV), this assumption may lead errors in quantification left ventricular mechanical dyssynchrony with phase analysis. We hypothesize a time-modified OSEM (TOSEM) algorithm...
Cardiac resynchronization therapy (CRT) is a treatment for patients with end-stage heart failure. However, two-thirds of the are nonresponders. Evaluation left ventricular mechanical dyssynchrony may help in finding who will benefit from CRT. Dyssynchrony can be evaluated by phase analysis method myocardial perfusion imaging (MPI) or cardiac ultrasound. The aim this study was to investigate reproducibility parameters MPI and echocardiographic evaluation dyssynchrony. In particular, influence...
Abstract Background Respiratory motion compromises image quality in myocardial perfusion (MP) single-photon emission computed tomography (SPECT) imaging and may affect analysis of left ventricular (LV) functional parameters, including phase analysis-quantified mechanical dyssynchrony parameters. In this paper, we investigate the performance two algorithms, respiratory blur modeling (RBM) joint motion-compensated (JMC) ordered-subsets expectation maximization (OSEM), effects compensation on...
Abstract Background and purpose: The interplay effects of respiratory motion MLC movement on the planned dose in right-sided whole-breast irradiation (WBI) were studied by simulating hypofractionated VMAT treatment courses. Materials methods: Ten patients with phase-triggered 4D-CT images included study. plans targeting right breast created retrospectively prescription doses 26 Gy (5 fractions) 40.05 (15 fractions). 3D-CRT generated as a reference. All divided into phase-specific...