Hailun Zhang

ORCID: 0000-0001-8679-8575
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About
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Research Areas
  • Bioinformatics and Genomic Networks
  • Evolutionary Game Theory and Cooperation
  • Reliability and Maintenance Optimization
  • Experimental Behavioral Economics Studies
  • Probabilistic and Robust Engineering Design
  • Perfectionism, Procrastination, Anxiety Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Evolutionary Psychology and Human Behavior
  • Air Quality Monitoring and Forecasting
  • Microbial Metabolic Engineering and Bioproduction
  • Cancer Genomics and Diagnostics
  • Obsessive-Compulsive Spectrum Disorders
  • Gene expression and cancer classification
  • Regional Socio-Economic Development Trends
  • Atmospheric aerosols and clouds
  • China's Socioeconomic Reforms and Governance
  • Urbanization and City Planning
  • Immune cells in cancer
  • Matrix Theory and Algorithms
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Remote Sensing and LiDAR Applications
  • Advanced biosensing and bioanalysis techniques
  • Regional Development and Environment
  • Cancer Immunotherapy and Biomarkers
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Northwestern Polytechnical University
2020-2022

Beijing VDJBio (China)
2022

North Minzu University
2021

Soochow University
2018

Center for High Pressure Science & Technology Advanced Research
2012

Abstract Immune checkpoint blockade (ICB) exhibits considerable benefits in malignancies, but its overall response rate is limited. Previous studies have shown that sphingosine kinases (SPHKs) are critical the tumor microenvironment (TME), their role immunotherapy unclear. We performed integrative analyses including bioinformatics analysis, functional study, and clinical validation to investigate of SPHK1 immunity. Functionally, we demonstrated inhibition significantly suppressed growth by...

10.1038/s41423-022-00911-z article EN cc-by Cellular and Molecular Immunology 2022-09-01

This study aimed to evaluate the effects of gender‐role types and child‐rearing attitude single‐parents, as well their children's gender role traits family socio‐economic status, on social adjustment. We recruited 458 pairs single parents children aged 8–18 by purposive sampling. The research tools included Family Socio‐economic Status Questionnaire, Sex Role Scales, Parental Child‐rearing Gender‐role Attitude Scale Social Adjustment Scale. results indicated: (a) mothers' daughters' feminine...

10.1002/ijop.12477 article EN International Journal of Psychology 2018-01-14

China has implemented the policy of reform and opening up for 40 years. Under infl uence this policy, China’s urbanization made great development progress. In index population urbanization, most obvious progress been made, both number cities, urban population, area have greatly increased, changing face ‘rural China’ in past. However, through in-depth comprehensive analysis, especially multidimensional analysis we can fi nd that there is a big gap between quality quantity two dimensions...

10.20339/am.02-24.091 article EN Alma mater Vestnik Vysshey Shkoly 2024-02-01

We used a random sample survey of 250 college students in Suzhou district China to explore the relationships among parenting behavior, perfectionism and obsessive-compulsive symptom, as well construct structural equation model. The results showed that students’ understanding behavior is above average, they have strong symptoms. College symptoms were affected by demographic variables, with gender grade having significant interaction; causes symptoms, played mediating role. Understanding...

10.4236/ce.2018.95057 article EN Creative Education 2018-01-01

In biological systems, gene expression is an important subject. order to clarify the specific process of expression, mathematical tools are needed simulate process. The Boolean network (BN) a good tool. this paper, we study with intermittent perturbations. This great significance for studying genetic mutations in bioengineering. genes internal system living being very complicated process, and it clear that trans-ageal humans. Through control pulse BN, can obtain trajectory better faster,...

10.1142/s0217984920503091 article EN Modern Physics Letters B 2020-08-05

The authors of this study adopted an approach from cognitive behavior modification to design a SMART strategy, and applied the intervention high school students. This used multiple baseline across-subject measure degree social anxiety among three students for duration 3 5 weeks, then strategy intervene document their mastering strategies changes 15 weeks. Their level was measured recorded 4 weeks after intervention. results showed that: 1) can be effectively address anxiety; 2) intervention,...

10.4236/ce.2017.812124 article EN Creative Education 2017-01-01

Due to the limitations of space or extra costs incurred, reliability optimization problem a spare system is great interest and importance. In this article, we devote our efforts into investigation warm gate cold gate. For with fixed components, first examine relationship between component order corresponding reliability; then, equivalence cascaded model multiple-input further presented. We find that for gate, value anticipated be affected by adopted replacing order; nevertheless, once...

10.1177/1748006x19895746 article EN Proceedings of the Institution of Mechanical Engineers Part O Journal of Risk and Reliability 2020-04-02

The object of this article is the cities China. rapid growth and impact Chinese upon economy, politics social life country South Eastern part world sparks persistent interest researchers. Urbanization processes in China has a range specific features that distinguish them from urbanization countries Western Europe. Their identification goal article. subject research became differentiation modern intraurban stratification. Based on accepted sociology methodology classification cities, author...

10.7256/2310-8673.2019.3.30657 article EN Урбанистика 2019-03-01

The <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$k$ </tex-math></inline-formula> -out-of- notation="LaTeX">$n$ : G(F) majority voter consists of n components (or modules) and a number the are required to be operating correctly for overall system correct. As per state discretization components, such is usually classified as either binary or multi-state system. In practice, conditions different may...

10.1109/access.2020.2977830 article EN cc-by IEEE Access 2020-01-01

Lidar, as an active remote sensing detection instrument, has become a powerful tool for atmospheric aerosol research. The extinction coefficient could be inverted by the lidar equation. However, traditional method required many assumptions and complicated calculations when inverting coefficient, which greatly limited accuracy efficiency of inversion. In this article, predicting using Elman neural network was proposed. model continuously trained to directly predict from echo signal,...

10.1109/iciea51954.2021.9516085 article EN 2022 IEEE 17th Conference on Industrial Electronics and Applications (ICIEA) 2021-08-01
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