A5018549624- Infrared Thermography in Medicine
- Thermography and Photoacoustic Techniques
- Infrared Target Detection Methodologies
- Advanced Semiconductor Detectors and Materials
- Semiconductor Quantum Structures and Devices
- Skin Protection and Aging
- Spectroscopy and Chemometric Analyses
- Cutaneous Melanoma Detection and Management
- Optical and Acousto-Optic Technologies
- Calibration and Measurement Techniques
- Obstructive Sleep Apnea Research
- Photonic and Optical Devices
- Bee Products Chemical Analysis
- Image Processing Techniques and Applications
- Ocular and Laser Science Research
- Quantum optics and atomic interactions
- Insect and Pesticide Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neuroscience of respiration and sleep
- Anomaly Detection Techniques and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Video Surveillance and Tracking Methods
- Spectroscopy and Laser Applications
- Identification and Quantification in Food
- Nanomaterials for catalytic reactions
University of Concepción
2008-2024
Universidad del Desarrollo
2017-2020
Clínica Alemana
2020
University of New Mexico
2011-2017
Pontificia Universidad Católica de Chile
2012
Instituto de Química y Fisicoquímica Biológicas
2002
Skin cancer is the most common in United States with over 3.5M annual cases. Presently, visual inspection by a dermatologist has good sensitivity (> 90%) but poor specificity (< 10%), especially for melanoma, which leads to high number of unnecessary biopsies. Here we use dynamic thermal imaging (DTI) demonstrate rapid, accurate and non-invasive system detection skin cancer. In DTI, lesion cooled down recovery recorded using infrared imaging. The curves suspected lesions are then utilized...
Gold nanoparticles (AuNPs) are currently under intense investigation for biomedical and biotechnology applications, thanks to their ease in preparation, stability, biocompatibility, multiple surface functionalities, size-dependent optical properties. The most commonly used method AuNP synthesis aqueous solution is the reduction of tetrachloroauric acid (HAuCl4) with trisodium citrate. We have observed variations pH concentration gold colloidal suspension synthesized standard conditions,...
In this paper, we report the initial demonstration of mid-infrared interband cascade (IC) photodetector focal plane arrays with multiple-stage/junction design. The merits IC photodetectors include low noise and efficient photocarrier extraction, even for zero-bias operation. By adopting enhanced electron barrier design a total absorber thickness 0.7 μm, 5-stage detectors show very dark current (1.10 × 10−7 A/cm2 at −5 mV 150 K). Even un-optimized fabrication standard commercial (mis-matched)...
In this article we present the development of a biosensor system that integrates nanotechnology, optomechanics and spectral detection algorithm for sensitive quantification antibiotic residues in raw milk cow. Firstly, nanobiosensors were designed synthesized by chemically bonding gold nanoparticles (AuNPs) with aptamer bioreceptors highly selective four widely used antibiotics field veterinary medicine, namely, Kanamycin, Ampicillin, Oxytetracycline Sulfadimethoxine. When molecules are...
The spatial fixed-pattern noise (FPN) inherently generated in infrared (IR) imaging systems compromises severely the quality of acquired imagery, even making such images inappropriate for some applications. FPN refers to inability photodetectors focal-plane array render a uniform output image when uniform-intensity scene is being imaged. We present noise-cancellation-based algorithm that compensates additive component FPN. proposed method relies on assumption source correlated available IR...
We present an instrument based on commodity embedded hardware, that implements automatic procedure for early skin-cancer screening using dynamic thermal imaging. The leverages image segmentation in the visible range and real-time multimodal registration to compute temperature recovery curve (TRC) of suspicious skin lesions infrared video. two algorithms infer malignancy lesion from computed TRCs. first algorithm assumes TRCs are deterministic infers distance between TRC its surrounding skin,...
We report on a systematic study of the effect barriers quantum dots-in-a-well infrared photodetectors. Four devices are fabricated and characterized with varying composition for adjacent to dots away from dots. Effects these "proximity" "remote" studied by comparing photoluminescence, responsivity, dark current, background-limited operating temperature, activation energy, detectivity. The growth mechanism conformal coverage proximity is described supported reflection high-energy electron...
While quantum dots-in-a-well (DWELL) infrared photodetectors have the feature that their spectral responses can be shifted continuously by varying applied bias, width of response at any bias is not sufficiently narrow for use in multispectral sensing without aid filters. To achieve higher resolutions using physical filters, algorithms been developed post-processing DWELL's bias-dependent photocurrents resulting from probing an object interest repeatedly over a wide range biases. At heart...
Gold nanoparticles (AuNPs) are currently under intense investigation for biomedical and biotechnology applications, thanks to their ease in preparation, stability, biocompatibility, multiple surface functionalities size-dependent optical properties. The most commonly used method AuNPs synthesis aqueous solution is the reduction of tetrachloroauric acid (HAuCl4) with trisodium citrate. We observed variations pH concentration gold colloidal suspension synthesized standard conditions, verifying...
Two model-based algorithms for edge detection in spectral imagery are developed that specifically target capturing intrinsic features such as isoluminant edges characterized by a jump color but not intensity. Given prior knowledge of the classes reflectance or emittance spectra associated with candidate objects scene, small set spectral-band ratios, which most profoundly identify between each pair materials, selected to define signature. The bands form signature fed into spatial mask,...
We describe an embedded system architecture that implements a real-time multimodal registration method which enables multicamera spatio-temporal feature extraction from the combination of visible and long-wave infrared image sequence. Image is performed by matching common features between each frame to sequence, in order estimate affine transformation pair images. The parameters this are estimated recursively on line with video, thus enabling real time. algorithm implemented using software...
It is shown how the quantum phase-space distribution of a continuous-wave (cw) optical beam can be obtained independently at each point in phase space by combination unbalanced homodyne and balanced-heterodyne techniques. The homodyning allows for local sampling space, whereas heterodyne part, although introducing loss detection efficiency, provides highly efficient reduction 1/f excess noise that required cw fields. method complements well-known techniques light pulses providing robust beams.
A new readout integrated circuit (ROIC) for multispectral classification is presented. The ROIC designed to utilize the spectral response tunability of dot-in-a-well (DWELL) infrared photodetector exploit possibility real-time on-chip imaging in analog domain. unit cells are include all necessary elements needed classification, including high-voltage time-varying positive and negative biases, bipolar integration, selective sample-and-hold circuits. test chip was fabricated using TSMC's 0.35...
The Interband Cascade (IC) detector with InAs/Ga(In)Sb type-II superlattice (T2-SL) absorbers is a new type of high-performance infrared photodetector that has many unique features. In this IC design, the T2-SL absorber sliced into multiple thinner segments are sandwiched between electron and hole barriers, forming one stage. Multiple stages electrically connected in series. asymmetric energy-band alignment ultra-fast carrier transport channel have enabled detectors to operate under/near...
There is an increasing interest in the development of high operating temperature (HOT) detectors with InAs/Ga(In)Sb Type-II superlattice (T2-SL) material systems. A wide variety unipolar barrier structures have been investigated and successfully implemented low-noise device architectures. In this paper, some our recent work on HOT mid-IR (MWIR) T2-SL photodetectors interband cascade schemes will be summarized. these structures, discrete InAs/GaSb SL absorbers are sandwiched between...
Infrared thermography is considered a useful technique for diagnosing several skin pathologies but it has not been widely adopted mainly due to its high cost. Here, we investigate the feasibility of using low-cost infrared cameras with microbolometer technology detecting cancer. For this purpose, collected data from volunteer subjects high-cost/high-quality camera. We propose degradation model assess use lower-cost imagers in such task. The was validated by mimicking video acquisition...