Juan Manuel Pérez-Zúñiga
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Multiple Myeloma Research and Treatments
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Neutropenia and Cancer Infections
- Hematological disorders and diagnostics
- Retinoids in leukemia and cellular processes
- Childhood Cancer Survivors' Quality of Life
- COVID-19 and healthcare impacts
- Amoebic Infections and Treatments
- Hemoglobinopathies and Related Disorders
- CNS Lymphoma Diagnosis and Treatment
- Platelet Disorders and Treatments
- Eosinophilic Disorders and Syndromes
- Hemophilia Treatment and Research
- Blood groups and transfusion
- Peptidase Inhibition and Analysis
- Cytomegalovirus and herpesvirus research
- Cardiovascular Function and Risk Factors
- Anorectal Disease Treatments and Outcomes
- Hemostasis and retained surgical items
- Protein Degradation and Inhibitors
Tecnológico Nacional de México
2024
Institute for Social Security and Services for State Workers
2011-2023
Mexican Social Security Institute
2023
Centro Médico ABC
2023
Hospital Español
2023
Hospital de Especialidades
2023
( Can J Anesth. 2024;71(4):548–549. doi:10.1007/s12630-024-02691-8) Vargas Zúñiga and George publish a case report on woman with known Marfan syndrome who gave birth through cesarean delivery (CD). The patient was 36 years old to have syndrome. This her first pregnancy, which full term (37+4 wk) at the time of presentation. To understand what limitations they needed consider for CD, magnetic resonance imaging (MRI) transthoracic echocardiography performed resulted in finding aortopathy...
The COVID-19 pandemic is a colossal challenge for global health; nonetheless, specific subgroups face considerably higher risks infection and mortality. Among patients with malignant diseases, those hematologic neoplasms are at risk poor outcomes. objective of this study was to register treatment modifications associated the their short-term consequences in Latin America.Multicenter, prospective, observational, cohort including older than 14 years from centers four countries (Mexico, Peru,...
Background: There is no epidemiological registry in Mexico. The information about the epidemiology our country obtained by these types of studies, such as multicentric studies. A lot improvements survival non-Hodgkin lymphoma patients had occurred last 20 years. access to treatment pathology could change prognostic factors Mexican Mestizos patients. primary objective study was learn what most frequent histological varieties Mexico are. secondary objectives included clinical characteristics,...
Acute myeloid leukemia (AML) comprises a heterogeneous group of hematopoietic cell neoplasms lineage that arise from the clonal expansion their precursors in bone marrow, interfering with differentiation, leading to syndrome marrow failure. AML is consequence genetic and epigenetic changes (point mutations, gene rearrangements, deletions, amplifications, arrangements influence expression) precursor cells, which create clone abnormal cells are capable proliferating but cannot differentiate...
Para identificar una patología cada vez más común, conocida como mieloma múltiple, es necesario hacer alusión de los factores específicos que la caracterizan. ello existen clásicos criterios conocidos CRAB (hipercalcemia, insuficiencia renal, anemia y lesiones líticas), siendo renal sus complicaciones frecuentes. Recientemente se han descrito tres biomarcadores indiscutibles para el apoyo diagnóstico del son: 10% células plasmáticas clonales en medula ósea o biopsia corrobora presencia un...
Myelofibrosis (MF) is a BCR-ABL1-negative myeloproliferative neoplasm characterized by clonal myeloproliferation, dysregulated kinase signaling, and release of abnormal cytokines. In recent years, important progress has been made in the knowledge molecular biology prognostic assessment MF. Conventional treatment limited impact on patients' survival; it includes wait-and-see approach for asymptomatic patients, erythropoiesis-stimulating agents, androgens, or immunomodulatory agents anemia,...
Essential thrombocythemia (ET) is a chronic Philadelphia-negative myeloproliferative neoplasm that has its main involvement in the megakaryopoietic lineage, generating sustained thrombocytosis peripheral blood and an increase number of mature megakaryocytes bone marrow. In addition to marked thrombocytosis, it characterized by increased thrombotic or hemorrhagic risk presence constitutional symptoms. Patients with ET have low but known disease progression myelofibrosis and/or acute leukemia....
Hemophilia is a hemorrhagic disorder with sex-linked inherited pattern, characterized by an inability to amplify coagulation due deficiency in factor VIII (hemophilia A or classic) IX B).Sequencing of the genes involved hemophilia has provided description and record main mutations, as well correlation various degrees severity.Hemorrhagic manifestations are related levels circulating factor, mainly affecting musculoskeletal system specifically large joints (knees, ankles, elbows).This...
The present retrospective study reviewed acute promyelocytic leukemia (APL) cases recorded in Mexico between January 2007 and 2017. primary objective of the was to evaluate overall survival (OS) Mexican patients with APL. Secondary impact induction treatment different anthracyclines on OS, event-free (EFS) complications this patient population.The medical charts referred institutions from through 2017 for suspected APL were retrospectively. Patients aged 15 - 75 years, whom diagnosis...
Hemophilia is a hemorrhagic disorder with sex-linked inherited pattern, characterized by an inability to amplify coagulation due deficiency in factor VIII (hemophilia A or classic) IX B). Sequencing of the genes involved hemophilia has provided description and record main mutations, as well correlation various degrees severity. Hemorrhagic manifestations are related levels circulating factor, mainly affecting musculoskeletal system specifically large joints (knees, ankles, elbows). This...
In Mexico, seroprevalence of Entamoeba histolytica is 8.4%. The intestinal amebiasis in patients with acute leukemia novo, after the start chemotherapy (CT) Hematology Service CMN 20 de Noviembre 12%, even if show a negative baseline coprological test.To find out administration tinidazole, and test, at beginning CT, decreases incidence amoebic colitis during induction to remission.Prospective not comparative study. Patients novo diagnosis who initiate initial CT. Tinidazole was indicated, 2...
To identify this increasingly common pathology, known as multiple myeloma (MM), it is necessary to refer the specific factors that characterize it; end, classic criteria CRAB (hyperkalemia, renal failure, anemia, and lytic lesions) are available, in which failure one of most frequent complications.Recently, three indisputable biomarkers have been described for diagnostic support MM, are: more than 10% clonal plasma cells bone marrow or, a biopsy corroborates presence plasmacytoma, light...
Hodgkin's lymphoma (HL) is due to the clonal transformation of cells originating from B lymphocytes, generating pathognomonic binucleate Reed-Sternberg cells.HL a cell disease with bimodal distribution, higher incidence in adolescence and third decade life, showing second peak people over 55 years age.Classic Hodgkin routinely undergo gene expression reprogramming, as they lose most typical B-cell genes acquire multiple that are other types immune system.The treatment algorithm will
El linfoma de Hodgkin (LH) se debe a la transformación clonal células originadas en los linfocitos B, lo que genera las binucleadas patognomónicas Reed-Sternberg. LH es una enfermedad B con distribución bimodal, mayor incidencia adolescencia y tercera década vida un segundo pico personas mayores 55 años. Las del clásico habitualmente sufren reprogramación expresión génica, ya pierden mayoría genes típicos han adquirido múltiples son otros tipos sistema inmunitario. algoritmo tratamiento...
To compare the lower uterine segment (LUS) appearance using 2D and 3D transvaginal ultrasound in term pregnant women with previous Caesarean section. This is a prospective cross-sectional study utilising evaluation of among 28 singleton pregnancies at least one history low transverse section scar. Lower thickness was compared to scar grading (I IV) on intraoperative findings during elective repeat Cesarean within 24 hours from measurement. Excluded were multiple gestation, polyhydramnios,...