A5015554910- Global Cancer Incidence and Screening
- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Eating Disorders and Behaviors
- Patient-Provider Communication in Healthcare
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Cancer survivorship and care
- Economic and Financial Impacts of Cancer
- Colorectal Cancer Screening and Detection
- Cancer Diagnosis and Treatment
- Medication Adherence and Compliance
- Urological Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Breast Cancer Treatment Studies
- Gastric Cancer Management and Outcomes
- Bladder and Urothelial Cancer Treatments
- Esophageal Cancer Research and Treatment
- Bipolar Disorder and Treatment
- Folate and B Vitamins Research
- MicroRNA in disease regulation
- Multiple and Secondary Primary Cancers
- Breast Implant and Reconstruction
- Prostate Cancer Diagnosis and Treatment
- Management of metastatic bone disease
University of Iowa
2016-2025
University of Iowa Holden Comprehensive Cancer Center
2014-2024
University of Nebraska Medical Center
2020
Iowa City Public Library
2014-2017
University of Illinois Hospital & Health Sciences System
2017
University of Illinois Chicago
2017
University of Iowa Hospitals and Clinics
2012-2015
Birmingham Women's Hospital
1988
Individuals with manifest Huntington's disease (HD) were interviewed regard to the presence, frequency, and severity of depression symptoms better characterize depressed mood across course in HD. Rates more than twice that found general population. One-half reported they had sought treatment for depression, 10% having at least one suicide attempt. The proportion HD patients endorsing significant diminished progression. Despite public health impact available treatments are underutilized HD,...
Chronic upper extremity disability (UED) is common after breast cancer treatment but under-identified and under-treated. Although UED has been linked to quality of life (QoL), the role as mediator between contemporary practices QoL not quantified. This investigation describes in a sample patients examines its relationship with personal factors QoL.Eight hundred thirty-three women diagnosed at eight medical institutions during 2013-2014 microscopically confirmed ductal carcinoma situ or...
For early-stage oral squamous cell carcinoma (OSCC), there is no existing risk-stratification modality beyond conventional TNM staging system to identify patients at high risk for cancer-specific mortality.A total of 568 OSCC who had surgery only and also with available 5-year clinical outcomes data were identified. Signature microRNAs (miRNAs) discovered using deep sequencing analysis validated by qRT-PCR. The final 5-plex prognostic marker panel was utilized generate a mortality score the...
Pancreatic resection is the standard treatment option for patients with stage I/II pancreatic ductal adenocarcinoma (PDA), yet many studies demonstrate low rates of resection. The objective this study was to evaluate whether increasing would result in an increase average survival PDA.SEER (Surveillance, Epidemiology, and End Results) data were analyzed head cancers treated from 2004 2009. Pancreatectomy examined within Health Service Areas (HSAs) across 18 SEER regions. An instrumental...
To validate the association between obesity and penile cancer at a population level, we conducted matched case-control study linking Iowa Department of Motor Vehicles Drivers' License Database (DLD) with surveillance data collected by State Health Registry (SHRI).All men diagnosed invasive squamous cell carcinoma from 1985 to 2010 were identified SHRI. Two hundred sixty-six cases 816 cancer-free male controls, selected DLD, within 5-year age calendar year strata. Body mass index (BMI) was...
ABSTRACT Purpose Differences in breast cancer recurrence and survival occur by body size; the role of treatment differences these disparities has been underexplored. Our objective was to evaluate treatments received, patient experiences care, decision‐making processes among survivors size. Methods We used data from Share Thoughts on Breast Cancer study. Participants ( n = 1198) completed a survey that included information demographics, quality decision‐making. descriptive statistics response...
Abstract Objective This study was conducted to determine whether neuropsychological dysfunction associated with anorexia nervosa resolves inpatient treatment. Method Subjects were 28 women being treated for nervosa. Main variables included body mass index (BMI), Beck Depression Inventory‐II, and test scores. tested at admission discharge. Results Neuropsychological functioning improved across the course of treatment, significant changes on tests memory psychomotor speed. improvement not...
The existence of cognitive deficits associated with eating disorders has been debated for some time. present study investigated impairments in a large sample patients anorexia nervosa from an inpatient treatment program. Fifty-nine women were given battery neuropsychological tests assessing multiple domains. Over half the had mild two or more tasks and approximately one-third failed tasks. Depression level body mass not impairment. Whether effective restoration weight resolution core...
Pancreatic ductal adenocarcinoma (PDAC) is characterized by early recurrence following pancreatectomy, rapid progression, and chemoresistance. Novel prognostic predictive biomarkers are urgently needed to both stratify patients for clinical trials select adjuvant therapy regimens. This study sought determine the biological significance of RABL6A (RAB, member RAS oncogene family-like protein 6 isoform A), a novel pancreatic protein, in PDAC. Analyses expression PDAC specimens from 73 who...
Abstract Background Colorectal cancer (CRC) screening has been shown to decrease the incidence of late‐stage colorectal cancer, yet a substantial proportion Americans do not receive screening. Those in rural areas may face barriers colonoscopy services based on travel time, and previous studies have demonstrated lower among residents. Our purpose was assess factors associated with CRC, specifically determine if longer time CRC an insured population Iowa. Methods SEER‐Medicare data were used...
Objectives . The study objective was to determine how insurance status relates treatment receipt and overall survival for patients with early-stage pancreatic exocrine carcinoma. Methods SEER data were evaluated 17,234 diagnosed Stage I/II Multivariate regression models controlled personal characteristics whether independently associated of radiation/surgery. Results Odds receiving radiation 1.50 1.75 times higher insured compared Medicaid uninsured patients, respectively (<mml:math...
Previous research has revealed cognitive deficits in patients with anorexia nervosa. It is unclear whether these are linked to co-morbid depression this population. We examined the relationship between depressive symptoms and functioning.A large sample of subjects (N = 98) was using a common measure ability two measures depression.We confirmed that there no group.This suggests alternative explanations be explored for
We hypothesized that the length of treatment-free survival following (a) initial diagnosis and (b) first-line treatment would be associated with improved subsequent five-year relative (RS5) in patients chronic lymphocytic leukemia or small lymphoma (CLL/SLL). 19,879 incident CLL/SLL cases (median age = 76 years) were identified from SEER-Medicare. RS5 0.73 (95% CI: 0.72, 0.74) at to 0.81 0.80, 0.82) year 1 0.89 0.83, 0.96) 10 among those who had not received treatment. In our analysis...
We investigated the stability of neuropsychological performance and eating disorder (EDO) symptoms before, immediately after, 2 years after inpatient treatment. also examined relationships between EDO measures.
To evaluate the completeness of information for research and quality assessment through a linkage between cancer registry data electronic health record (EHR) refined by ASCO's technology platform CancerLinQ.