- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Bee Products Chemical Analysis
- Nuts composition and effects
- Phytochemistry and Biological Activities
- Fermentation and Sensory Analysis
- Food Quality and Safety Studies
- Occupational Health and Performance
- Air Quality and Health Impacts
- Plant biochemistry and biosynthesis
- Skin Protection and Aging
- Advancements in Transdermal Drug Delivery
- Natural Antidiabetic Agents Studies
- Insect and Pesticide Research
- Natural product bioactivities and synthesis
- Coffee research and impacts
- Phytoestrogen effects and research
- Subcritical and Supercritical Water Processes
- Botanical Research and Applications
- Oral health in cancer treatment
- Antioxidant Activity and Oxidative Stress
- Tannin, Tannase and Anticancer Activities
- Fungal Biology and Applications
- Tea Polyphenols and Effects
- Edible Oils Quality and Analysis
Polytechnic Institute of Porto
2019-2025
Rede de Química e Tecnologia
2016-2025
Universidade do Porto
2012-2024
Laboratório Associado para a Química Verde
2024
University of Coimbra
2024
Universidade Federal de Viçosa
2024
Instituto Superior de Engenharia do Porto
2019-2023
University of Minho
2023
Leipzig University
2020
University of Helsinki
2015
Aging is a natural and progressive declining physiological process that influenced by multifactorial aspects affects individuals’ health in very different ways. The skin one of the major organs which aging more evident, as it progressively loses some its functions. With new societal paradigms regarding youth beauty have emerged concerns about appearance, encouraging millions consumers to use cosmetic/personal care products part their daily routine. Hence, cosmetics become global highly...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with very poor prognosis. Its treatment hindered by lack of new therapeutic alternatives and the existence blood–brain barrier (BBB), which restricts access drugs commonly used in ALS, such as riluzole, to brain. To overcome these limitations increase brain targeting, riluzole-loaded nanostructured lipid carriers (NLC) were prepared functionalized lactoferrin (Lf), facilitating transport across BBB interacting Lf receptors...
Chestnut (Castanea sativa) shells (CSs), an undervalued agro-industrial biowaste, have arisen as a source of bioactive compounds with promising health-promoting effects. This study attempted, for the first time, to develop functional food, namely cookies, using CS extract obtained by eco-friendly technology (subcritical water extraction). The cookies were characterized regarding their nutritional composition, total phenolic and flavonoid contents (TPC TFC, respectively),...
Pistacia vera shells, an abundant agricultural by-product, are a rich source of undiscovered bioactive compounds. This study employed response surface methodology (RSM) approach to optimize the microwave-assisted extraction antioxidants. The highest total phenolic content, and antioxidant activity were achieved under optimized conditions (20% ethanol, 1000 W, 135 s, solvent-to-solid ratio 27 mL/g). resulting extract (OPVS-E) included gallic acid derivatives, hydrolysable tannins, flavonoids,...
Context: Currently, there is a great tendency in cosmetic area to use natural extracts. Coffee silverskin (CS) the most abundant solid by-product generated during roasting of coffee processing.Objectives: To evaluate different CS extracts as promising ingredients, regarding antioxidant, antimicrobial, and cytotoxic properties.Materials methods: Aqueous, hydroalcoholic ethanolic were obtained by an environmentally friendly procedure considering costs pollution. Extracts characterized for...
Chestnut processing industry generates large amounts of by-products, including leaves, burs and shells that are a source bioactive compounds. The purpose this study was to establish an ultrasound-assisted extraction (UAE) phenolic antioxidant compounds from industrial chestnut shells. A central composite design (CCD) conducted analyze the effects time (4-46 min) temperature (34-76 °C) in activity (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS), 2,2-diphenyl-1-picrylhydrazyl...
cultivar, native in the Mediterranean basin, has expanded worldwide, mainly due to olive oil industry. This expansion is attributed benefits of consumption, since this product rich nutritional and bioactive compounds. However, industry generates high amounts wastes, which could be related polluting effects on soil water. To minimize environmental impact, different strategies revalorization have been proposed. In sense, aim work was develop cosmetic value added oleuropein-enriched extracts...
Chestnuts (Castanea sativa) are valuable fruits that extremely economically important for south European mountainous regions. During chestnut processing, large amounts of C. sativa shells (CSS), an undervalued byproduct, generated without any economic or social profit. The aim this paper was to employ microwave-assisted extraction (MAE) recover polyphenols from CSS using different eco-friendly solvents (water and ethanol). influence the on total phenolic flavonoid content (TPC TFC,...