Valentin Dettling

ORCID: 0000-0001-8811-1693
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Microplastics and Plastic Pollution
  • Education, sociology, and vocational training
  • Social Policies and Family
  • SARS-CoV-2 and COVID-19 Research
  • Bacteriophages and microbial interactions
  • Escherichia coli research studies
  • Vibrio bacteria research studies
  • Virus-based gene therapy research
  • School Health and Nursing Education
  • vaccines and immunoinformatics approaches
  • Marine Biology and Environmental Chemistry
  • Coastal Management and Development
  • Recycling and Waste Management Techniques
  • Environmental Engineering and Cultural Studies
  • Psychoanalysis and Psychopathology Research
  • SARS-CoV-2 detection and testing
  • Transgenic Plants and Applications

Éco-Anthropologie
2024

Institut de Systématique, Évolution, Biodiversité
2024

CEA Grenoble
2021-2022

Centre National de la Recherche Scientifique
2021-2022

Institut de Biologie Structurale
2021-2022

Université Grenoble Alpes
2021-2022

Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2021-2022

École Normale Supérieure de Lyon
2019

Virus-like particles (VLPs) are highly suited platforms for protein-based vaccines. In the present work, we adapted a previously designed non-infectious adenovirus-inspired 60-mer dodecahedric VLP (ADDomer) to display multimeric array of large antigens through SpyTag/SpyCatcher system. To validate platform as potential COVID-19 vaccine approach, decorated newly with glycosylated receptor binding domain (RBD) SARS-CoV-2. Cryoelectron microscopy structure revealed that up 60 copies this...

10.1016/j.ymthe.2022.02.011 article EN cc-by-nc-nd Molecular Therapy 2022-02-10

While the production of plastic has been ever-increasing since 1950s, little is known about temporal dynamics pollution. Microplastics (less than 5 mm) represent majority total pollution in terms particle number. stem mainly from breakdown larger items, and can sink onto ocean floor due to their own density or after biofilm formation. Consequently, microplastics accumulate on particularly deep-ocean floor, turning this poorly understood ecosystem into a major microplastic sink. are easily...

10.5194/oos2025-22 preprint EN 2025-03-25

Microplastic pollution has risen to such a level that concerns are being raised regarding its consequences on the environment, especially marine environment. Understanding microplastic temporal dynamics is critical but requires time-series. However, about recent, long term monitoring programs have only started very recently and remain scarce. Natural History Collections represent archives from past can constitute Although underused, they evinced their success study various stressors...

10.1016/j.ecolind.2024.111894 article EN cc-by-nc-nd Ecological Indicators 2024-03-01

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has shown that vaccine preparedness is critical to anticipate a fast response emergent pathogens with high infectivity. To rapidly reach herd immunity, an affordable, easy store and versatile platform thus desirable. We previously designed non-infectious adenovirus-inspired nanoparticle (ADDomer), in the present work, we efficiently decorated this original glycosylated receptor binding domain (RBD) of...

10.1101/2021.09.13.460076 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2021-09-13
Coming Soon ...