- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Pharmacology and Obesity Treatment
- High Altitude and Hypoxia
- Physical Activity and Health
- Metabolism, Diabetes, and Cancer
- Lysosomal Storage Disorders Research
- Glycogen Storage Diseases and Myoclonus
- Diabetes Management and Education
- Health and Lifestyle Studies
- Laser Applications in Dentistry and Medicine
- Child Nutrition and Feeding Issues
- Non-Invasive Vital Sign Monitoring
- Autoimmune and Inflammatory Disorders Research
- Cancer survivorship and care
- Cancer-related cognitive impairment studies
- Childhood Cancer Survivors' Quality of Life
- Cardiovascular Function and Risk Factors
- Children's Physical and Motor Development
- Tendon Structure and Treatment
- Inflammatory Bowel Disease
- Microscopic Colitis
- Bee Products Chemical Analysis
Erasmus MC
2010-2022
Wilhelmina Children's Hospital
2022
University Medical Center Utrecht
2022
Erasmus University Rotterdam
2015
Musculotendinous overuse injuries are prevalent in people with type 2 diabetes. Non-enzymatic glycosylation of collagen resulting tendon stiffening may play a role. In this case-control study we determined whether patients diabetes had poorer ultrasonographic structure their Achilles tendons compared to age-matched controls.People 1 or diabetes, and controls, computerised ultrasound tissue characterisation both tendons. contiguous images the tendon, echopatterns were quantified categorised...
To assess physical fitness and activity in inflammatory bowel disease (IBD) patients whether fatigue is associated with impaired activity.Ten quiescent IBD (fatigue group [FG]) based on the Checklist Individual Strength-Fatigue score of ≥35 were matched for age (±5 years) sex a non-fatigue (NFG) IBD. Physical was measured cyclo-ergometric-based maximal exercise test, submaximal 6-min walk dynamometer test to quantify isokinetic muscle strength knee extensors flexors. Level an...
The study investigated the feasibility and potential outcome measures during acute hyperoxia in type 2 diabetes patients (DM2). Eleven DM2 (7 men 4 women) were included study. cycled (30 min at 20% Wmax) whilst breathing three different supplemental oxygen flows (SOF, 5, 10, 15 L min(-1)). During hyperoxic exercise, arterial blood gases intra-arterial pressure measurements obtained. Arterial pO2 levels increased significantly (ANOVA, p < 0.05) with SOF: 13.9 ± 1.2 (0 min(-1)); 18.5 1.5 (5...
Abstract Objective The purpose of the present study was to investigate association between cardiorespiratory fitness (CRF) measured as peak oxygen uptake (VO 2peak , expressed in mL/min) and body mass index (BMI) a large cohort apparently healthy subjects. Methods BMI VO were cross-sectional 8470 adults. (mL/min) determined by an incremental cycle ergometer test exhaustion. Linear regression analyses performed identify predictors CRF. Results There no difference CRF adults with normal weight...
A short maximal steep ramp test ( SRT , 25 W /10 s) has been proposed to guide exercise interventions in type 2 diabetes, but requires validation. This study aims (a) determine the relationship between max and reached during standard RT ); (b) obtain test‐retest reliability; (c) document electrocardiogram ECG ) abnormalities . Type diabetes patients (35 men, 26 women) performed a cycle ergometer‐based (women 1.2; men 1.8 /6 on separate days. random subgroup n = 42) repeated heart rate, were...
Mankowski, RT, Michael, S, Rozenberg, R, Stokla, Stam, HJ, and Praet, SFE. Heart-rate variability threshold as an alternative for spiro-ergometry testing: a validation study. J Strength Cond Res 31(2): 474-479, 2017-Although is the established "gold standard" determination of second ventilatory (VT2), it costly rather time-consuming method. Previous studies suggest that assessing anaerobic (AT2) on basis heart rate (HRV) during exercise may be more cost-effective noninvasive manner. However,...
To evaluate physical fitness and its association with fatigue in patients low grade glioma (LGG).Cross-sectional study. Muscle strength was measured a digital dynamometer, cardiorespiratory (peak oxygen uptake (VO2peak), maximal workload (MWL)) by cardiopulmonary-exercise-testing, using the Multidimensional Fatigue Inventory.Thirty were included, mean age of 44.1 (SD11.2) years, 67% men, 31.2 (SD18) months post-diagnosis. (p < 0.01), (VO2peak, MWL) 0.01) significantly decreased compared to...
Pompe disease is a metabolic myopathy caused by the deficiency of acid α-glucosidase. In addition to enzyme replacement therapy (ERT), exercise training may help improve patients’ fitness and physical functioning. Thus, we studied safety efficacy in adult patients.