A5014817930- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Neurological Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Cardiovascular Health and Disease Prevention
- Intraocular Surgery and Lenses
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Retinopathy of Prematurity Studies
- Nitric Oxide and Endothelin Effects
- Lysosomal Storage Disorders Research
- Retinal Development and Disorders
- Ophthalmology and Eye Disorders
- Ocular Diseases and Behçet’s Syndrome
- Neonatal Respiratory Health Research
- Ocular Infections and Treatments
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Ocular Oncology and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Antioxidant Activity and Oxidative Stress
- Dermatologic Treatments and Research
University Medical Center Hamburg-Eppendorf
2011-2020
Universität Hamburg
2011-2020
Klinik und Poliklinik für Augenheilkunde Universitätsklinikum Regensburg
2006-2019
Ophthalmology Clinic
2007-2018
Museum am Rothenbaum
2018
Eppendorf (Belgium)
2012-2014
Eppendorf (Germany)
2005-2008
Universitäts-Augenklinik Bonn
2006
To investigate the influence of lag time between onset central visual acuity loss and surgical intervention macula-off retinal detachment.This retrospective case series examined all consecutively treated eyes with primary detachment at University Hospital Hamburg (Germany) from February 2010 to 2015. Records 1727 patients operated by six surgeons were reviewed. Eighty-nine (5.2%) 89 met inclusion exclusion criteria. The main outcome measure studied was final as a function symptom duration...
Purpose.: To analyze the neuroprotective effect of intravitreally grafted neural stem (NS) cells genetically modified to secrete ciliary neurotrophic factor (CNTF) on intraorbitally lesioned retinal ganglion (RGCs) in adult mice. Methods.: Adherently cultivated NS were express a secretable variant mouse CNTF together with fluorescent reporter protein Venus. Clonal CNTF-secreting cell lines established using fluorescence activated sorting, and into mice 1 day after an intraorbital crush optic...
The German retinopathy of prematurity (ROP) Registry collects data on treated ROP in a multicentre approach to analyse epidemiology and treatment patterns severe ROP.Nine centres entered from 90 infants (born between January 2011 December 2013) into central database. Analysis included incidence rate ROP, demographic data, stage patterns, recurrence rates, relevant comorbidities ophthalmological or systemic complications associated with treatment.Treatment for was 3.2% the screened...
Abstract Background Reduced choroidal perfusion is hypothesized to play a role in the pathogenesis of normal tension glaucoma. Thus impact antiglaucomatous eye drops on ocular has been focus recent research and subject intensive investigations. The present study investigates whether topically applied latanoprost or bimatoprost influence patients with glaucoma compares these effects that changes detected after treatment dorzolamide. Methods Ocular hemodynamics were assessed by color Doppler...
PURPOSE: To compare the efficacy, safety, predictability, and vector analysis indices of LASIK photorefractive keratectomy (PRK) for correction high cylinder greater than 3 diopters (D) in myopic eyes. METHODS: The predictability or PRK performed 114 consecutive randomly selected eyes with an astigmatism D were retrospectively analyzed at 2- to 6-month follow-up visits. Vector cylindrical was compared between treatment groups. RESULTS: A total 57 receiving refractive surgery candidates...
Uveamelanome sind die häufigsten malignen Augentumoren. Mit modernen molekularbiologischen Methoden (Chromosom-3-Typisierung, Genexpressionsanalyse) können weniger aggressive von hoch aggressiven Verlaufsformen (Monosomie 3, Klasse II) unterschieden werden. Diese molekularbiologische Stratifizierung hat bisher ausschließlich eine Bedeutung für Risikoeinschätzung, da es keine wirksame Therapie gibt, Metastasierung verhindern oder verzögern kann. Eine randomisierte Studie mit einer...
<h3>Aims</h3> Juvenile CLN3 disease, one of the most common forms a group lysosomal storage diseases called neuronal ceroid lipofuscinoses (NCLs), is progressive neurodegenerative disorder with initial visual deterioration. The objective this study was to analyse retinal phenotype patients disease help recent ophthalmic imaging modalities distinguish from other inherited dystrophies. <h3>Methods</h3> Patients underwent evaluations, including anterior and posterior segment examinations,...
To examine vision-related quality of life in patients with diabetic macular edema (DME) treated intravitreal aflibercept (EYLEA, Regeneron Pharmaceuticals, Inc, Tarrytown, NY). AQUA was a multicenter, open-label, single-arm, phase 4 study. Adults 18 years age or older type 1 2 diabetes mellitus and DME. Patients received mg every 8 weeks for 52 weeks, after 5 initial doses weeks. The primary outcome the change 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) total...
Abstract Background Fabry disease (FD) is an X-linked inherited storage disorder caused by deficiency of lysosomal alpha-Galactosidase A. Here we describe new retinal findings in patients with FD assessed Spectral domain optical coherence tomography (SD-OCT) and their possible clinical relevance. Methods 54 eyes 27 control subjects were included. The ophthalmic examination included visual acuity testing, tonometry, slit lamp fundus examination. SD-OCT imaging the macula was performed all...
Introduction Intraocular hemorrhage in patients suffering from aneurysmal subarachnoid is known as Terson's syndrome and an underestimated but common pathology. We therefore designed a prospective single-blinded study to evaluate the validity of ocular ultrasound compared gold standard indirect funduscopy diagnosis syndrome. Material Methods Fifty-two (104 eyes total) were enrolled this study. Two investigators independently performed using intensive care system detect intraocular...
Purpose.: Perfusion of the retina adapts to metabolic demand by neurovascular coupling. The present study was an investigation presence coupling in anterior part optic nerve healthy subjects and patients with glaucoma. Methods.: Retrobulbar blood flow velocities were determined color Doppler imaging (CDI). Peak systolic end diastolic (PSVs EDVs) central retinal artery (CRA) or short posterior ciliary (SPCA) primary readout. CDI measurements performed shortly before, during, immediately...