- Mechanical Circulatory Support Devices
- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Fuel Cells and Related Materials
- Diamond and Carbon-based Materials Research
- Dental materials and restorations
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Tissue Engineering and Regenerative Medicine
- Dental Implant Techniques and Outcomes
- Hemoglobin structure and function
- Metal and Thin Film Mechanics
- Hydraulic and Pneumatic Systems
- Engineering Applied Research
- Respiratory Support and Mechanisms
- Cardiac and Coronary Surgery Techniques
- Orthopaedic implants and arthroplasty
- Soft Robotics and Applications
- Prosthetics and Rehabilitation Robotics
- Electric and Hybrid Vehicle Technologies
- Analytical Chemistry and Sensors
- Balance, Gait, and Falls Prevention
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Neuroscience and Neural Engineering
Osaka Metropolitan University
2022-2025
Tokyo Metropolitan University
2024-2025
Maruho (Japan)
2024
Osaka City General Hospital
2020-2023
Institute of American Indian Arts
2019
Osaka City University
2017-2018
Sumitomo Hospital
2018
Osaka University
1998-2017
Higashi Nagoya National Hospital
2017
Tokyo Denki University
2006-2015
In this paper, we attempted to classify the acceleration signals for walking along a corridor and on stairs by using wavelet-based fractal analysis method. addition, method was used evaluate gait of elderly subjects patients with Parkinson's disease. The triaxial were measured close center gravity body while subject walked up down continuously. Signal measurements recorded from 10 healthy young 11 subjects. For comparison, two disease participated in level walking. signal each direction...
Oligosaccharides are increasingly being recognized as important partners in receptor−ligand binding and cellular signaling. Surface plasmon resonance (SPR) is a very powerful tool for the real-time study of specific interactions between biological molecules. We report here an advanced method immobilization oligosaccharides clustered structures SPR their application to analysis heparin−protein interactions. Reductive amination reactions linker molecules were designed optimized. Using mono-,...
The authors describe an 18-compartment hybrid computer multiple model of the uptake and distribution halothane. This uses 88 equations 124 parameter settings. Three submodels are incorporated into basic model: 1) mass transport halothane is simulated on digital portion computer. 2) A breath-by-breath pulmonary with two compartments describes air pressure-flow relations in airway system. 3) beat-to-beat cardiovascular 15 detail blood relations. In addition, a baroreceptor-heart rate loop...
Abstract Background and Objective: The Lysyl oxidase (LOX) family comprises enzymes that physiologically participate in the cross-linking of extracellular matrix components such as collagen elastin, thereby playing roles cell differentiation tissue formation. In tumor microenvironment, LOX is known to contribute remodeling cancer stroma influence metastasis differentiation. Our previous studies have reported associations between LOX, LOX-like (LOXL)2, prognosis gastric cancer. this study, we...
We attempted to classify walking on level ground from a stairway using waist acceleration signal. A tri-axial accelerometer was fixed the subject's and three signals were recorded by portable data logger at sampling rate of 256 Hz. Eleven healthy, elderly subjects asked walk through corridor up down as single sequence, without any instruction. The analyzed discrete wavelet transform. Walking patterns classified two parameters; one ratio between power coefficients which corresponded...
Scaffolds play a key role in the process of regeneration and morphogenesis tissue or organ. We have developed novel sonication decellularization system to prepare decellularized bio-scaffolds short treatment time. The aim study is investigate condition that completely decellularize meniscus can be changed as well maintain biomechanical parameters scaffolds. samples were using treatment. treated evaluated histologically by EVG for cell removal, picrosirius red content collagen type I III,...
Abstract: In this study we have attempted to classify the acceleration signal, while walking both at horizontal level, and upstairs downstairs, using wavelet analysis. The signal close body’s center of gravity was measured subjects walked in a corridor up down stairway. data for four steps were analyzed Daubecies 3 transform applied sequential data. variables be discriminated waveforms related levels -4 -5. sum square values each step compared Downstairs could from other types walking,...
There is currently an increasing interest in the use of DLC (diamond like carbon) films biomedical applications. These investigations making area indicate its attractive properties. In this study, we succeeded depositing on polymer substrates and found best conditions method for application. We evaluated blood compatibility polycarbonate coated by (PC-DLC) under different using epifluorescent video microscopy (EVM) combined with a parallel plate flow chamber. Segmented polyurethane (SPU),...
The noise behavior of self-pulsation lasers is investigated. It shown that the pulsation frequency an important factor in achieving low-noise characteristics under optical feedback. To obtain lasers, AlGaAs laser which has a ridge-waveguide self-aligned structure grown by OMVPE (organometallic vapor-phase epitaxy) been developed. Low-noise (relative intensity <<1*10/sup -13/ Hz/sup -1/) feedback approximately 3% are obtained controlling frequency.< <ETX...
The shortage of nurses in large hospitals developed countries has become a major problem. Especially, the scrub nurses, who assist operating surgeons exchange surgical instruments, been chronically severe. To compensate for this shortage, we have proposing nurse robot (SNR) system that is capable functioning as skilled human endoscopic and laparoscopic surgery. We 2nd version SNR, achieved smooth wide movement its arms each with 4 DOF. SNR able to speak several sentences recognize some words...
Abstract: Considering a miniaturization of percutaneous cardiopulmonary support (PCPS) system, we have developed pump system that can estimate flow rate and pressure head in the circuit. A commercially available centrifugal blood (C1E3, Kyocera Co., Ltd., Kyoto, Japan) with an exclusive motor driver was used experiment. In this revolutions per minute torque were to derive estimation equation. Taking into consideration fluid viscosity, accuracy increased. Bovine evaluate vitro. The average...
We attempted to distinguish walking on level ground from a stairway using waist acceleration signal. A triaxial accelerometer was fixed the and three signals were recorded by portable data logger at sampling rate of 256 Hz. Twenty healthy male subjects asked walk through corridor, or up down continuously without any instruction. The analyzed discrete wavelet transform. Walking patterns classified according two steps. At first step, times when pattern changed detected low-frequency component...