A5101674853- Mitochondrial Function and Pathology
- Diabetes and associated disorders
- Health and Wellbeing Research
- Glaucoma and retinal disorders
- Colorectal Cancer Screening and Detection
- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Pancreatic and Hepatic Oncology Research
- Plant Virus Research Studies
- Ubiquitin and proteasome pathways
- Cellular transport and secretion
- Pancreatitis Pathology and Treatment
- Heme Oxygenase-1 and Carbon Monoxide
- Connexins and lens biology
- ATP Synthase and ATPases Research
- Skin Protection and Aging
- Consumer Perception and Purchasing Behavior
- Ion Transport and Channel Regulation
- Metabolism and Genetic Disorders
- RNA regulation and disease
- Ophthalmology and Visual Impairment Studies
- Diabetes Management and Research
- Gastric Cancer Management and Outcomes
- Genomics and Rare Diseases
- Phytochemical compounds biological activities
Wonkwang University
2024
Yonsei University
2015-2024
University of California, Irvine
2021-2022
Konyang University
2021
University of Ulsan
2006-2019
Ulsan College
2006-2019
Asan Medical Center
2006-2019
Kangwon National University
2018
National Health Insurance Service
2015-2017
National Health Insurance Service Ilsan Hospital
2015-2017
We analysed risk factors to predict the recurrence of nephrotic syndrome and therapeutic efficacy plasmapheresis combined with oral cyclophosphamide (PE+CPM) in early recurrent after transplantation children focal segmental glomerulosclerosis (FSGS).Medical records 1990 16 biopsy-proven idiopathic FSGS renal before age 18 years were reviewed.Early developed six cases (37. 5%). While kidney graft biopsies, performed within first week onset recurrence, revealed diffuse effacement foot process...
Infantile nystagmus syndrome (INS) is a group of disorders presenting with genetic and clinical heterogeneities that have challenged the diagnoses INS. Precise molecular diagnosis in early infancy may result more accurate counseling improved patient management.
In this study, we investigated medically or surgically actionable genes in inherited eye disease, based on clinical phenotype and genomic data. This retrospective consecutive case series included 149 patients with diseases, seen by a single pediatric ophthalmologist, who underwent genetic testing between 1 March 2017 28 February 2018. Variants were detected using target enrichment panel of 429 known deep intronic variants associated disease. Among patients, 38 (25.5%) had family history,...
Prior research contends that social support positively influences health by optimizing individuals' psychological processes such as appraisals, emotions, and sense of control-known stress-buffering effects. This study tests this theoretical concept examining whether the association between can be explained perceived stress distress among Chinese Korean American immigrants. Furthermore, we examine what predicts in population, with a particular focus on factors related to immigration. Using...
Purpose: To evaluate incident cataract surgery in subjects who started hemodialysis for end-stage renal disease. Methods: A nationwide propensity score–matched cohort study was performed by using a 12-year longitudinal national health insurance database of 1,025,340 subjects. The composed patients between January 2003 and December 2007 (n = 291). control randomly selected (5 per patient the cohort; n 1467) were matched to according score based on year initiation, age, sex, residential area,...
The epidemiology of colorectal neoplasm in liver transplantation recipients has not been fully determined.The aim this study was to evaluate the prevalence and compare it with that average-risk population.This retrospective observational.This conducted at a tertiary care center.From January 2000 December 2011, 257 who had undergone posttransplant colonoscopy were enrolled. A total 1028 control subjects matched for age, sex, calendar year index recruited from those screening our...
Deletion polymorphism of angiotensin I converting enzyme <i>(ACE)</i> gene has been studied as a risk factor in various cardiovascular diseases and chronic nephropathies. Perturbation local systemic renin-angiotensin systems is one the possible mechanisms progression reflux nephropathy. In this study, implication <i>ACE </i>gene renal scarring deterioration function was analyzed 66 children with vesicoureteral reflux. The genotype for determined by PCR, scar...
To develop a strategy for improved production of clavulanic acid (CA), we investigated the effect using oils on cell growth and CA during fermentation Streptomyces clavuligerus NRRL 3585. In this analysis, triolein, whose fatty is oleic only, was best oil source production, but free acids generated from hydrolysis in culture broth negatively impacted growth. Hence, screened mutants that were resistant to high concentrations acid. From screen identified mutant S. clavuligerus, OL13, had...
Objective To determine the incidence of retinitis pigmentosa (RP) in South Korea. Design Nationwide, population-based retrospective study. Setting Census population Korea Participants This study involved entire (n=47 990 761). Patients confirmed as having RP by an ophthalmologist from 1 January 2011 to 31 December 2014 were included. Primary outcome measure The average during 4-year period was estimated using data 2010 Korean census. Results A total 3144 (1567 men and 1577 women) patients...
A 45-year-old Korean woman visited our hospital complaining of poor vision after carbon monoxide (CO) poisoning. We have confirmed the presence a point mutation at position 11778 in ND4 gene mitochondrial DNA. This case suggests that CO poisoning may precipitate clinical expression Leber's hereditary optic neuropathy (LHON). To knowledge, this would be first report LHON precipitated by
We describe patients with isolated small-bowel angioedema caused by allergic reactions to intravenous contrast media. Computed tomography (CT) revealed circumferential thickening of the walls duodenum or jejunum. Follow-up follow-through, endoscopy, and CT showed normalized loops. Transient findings on suggest angioedema.
The Association between Symptoms of Dry Eye Syndrome and Metabolic Outcome in a General Population Korea eye syndrome (DES) is recognized as public health concern.One the pathophysiologies development DES inflammation, metabolic (MetS), which highly prevalent general population, well-known chronic systemic inflammatory condition.Despite increasing interest regarding relationship MetS, information lacking on association MetS its individual components.We investigated symptoms components among...
AbstractPurpose/Background: To report the association of optic neuropathy and mitochondrial trnaLeu(uur) A3243G mutation which is known to be responsible for melas (mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes), diabetes mellitus with deafness, progressive external opthalmoplegia. Pigmentary retinopathy, opthalmoparesis, ptosis have been relatively frequently reported associated in literature. However, atrophy has rarely mutation. Methods: Analyses including...
The clinical significance of incidental pancreatic cystic lesions (PCLs) remains unclear in those that are not accompanied by worrisome features or high-risk stigmata. We aimed to investigate the natural course PCLs without any risk and examine factors associated with their progression.We conducted a retrospective cohort study 427 patients PCLs, which were incidentally detected computed tomography between January 2003 December 2012. Progression progression investigated. length time...
A cryopreservation condition for d-amino acid oxidase (DAAO)-overexpressing Escherichia coli (E. BL21(DE3)/pET-DAAO) was established. Ten percent the optimum concentration of glycerol as a cryoprotectant, and its diffusion into stationary phase cells superior to that log cells. The results also showed rather than fast cooling, slow cooling method appropriate our recombinant E. coli. In addition, 15 min best equilibration period, at which higher 90% recovery rates were maintained all test...
Purpose: To investigate the gender-specific associations between perceived vision impairment and symptoms of depression.Methods: We used data from 2012 Korean Longitudinal Study Aging database 7448 individuals aged 45 years older. Questionnaires assessing depression visual at near, distance, in general were administered. Logistic regression analyses to evaluate if could lead depression, adjusting for potential confounders age, socioeconomic status (household income, education level, marital...