A5054845482- Ultrasound in Clinical Applications
- Sepsis Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Nosocomial Infections in ICU
- Cardiac Arrest and Resuscitation
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Congenital Diaphragmatic Hernia Studies
- Cardiac Structural Anomalies and Repair
- Intensive Care Unit Cognitive Disorders
- Neonatal and Maternal Infections
- Phonocardiography and Auscultation Techniques
- Tracheal and airway disorders
- Respiratory viral infections research
- Antibiotic Resistance in Bacteria
- Heart Failure Treatment and Management
- Emergency and Acute Care Studies
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Radiology practices and education
- Hemodynamic Monitoring and Therapy
- Pleural and Pulmonary Diseases
Universitat de Barcelona
2016-2025
Hospital Sant Joan de Déu Barcelona
2015-2025
Institut de Recerca Sant Joan de Déu
2022
Sant Joan de Déu Research Foundation
2021
Bronchiolitis is the most common viral infection of lower respiratory tract in infants under 2 years age. The aim this study was to analyze and compare seasonal bronchiolitis peaks before during SARS-CoV-2 pandemic.Descriptive, prospective, observational study. Patients with severe admitted Pediatric Intensive Care Unit (PICU) a referral tertiary hospital between September 2010 June 2021 were included. Demographic data collected. Viral laboratory-confirmation carried out. Each season...
Abstract Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has collapsed health systems worldwide. In adults, the virus causes distress (ARDS), while in children disease seems to be milder, although a multisystem inflammatory (MIS-C) been described. aim was describe and compare characteristics of COVID-19 adults children. Methods This prospective observational cohort study included young infected with SARS-CoV-2 between March–June 2020 admitted paediatric intensive...
Purpose
Abstract Background Pneumonia is a major public health problem with an impact on morbidity and mortality. Its management still represents challenge. The aim was to determine whether new diagnostic algorithm combining lung ultrasound (LUS) procalcitonin (PCT) improved pneumonia regarding antibiotic use, radiation exposure, associated costs, in critically ill pediatric patients suspected bacterial (BP). Methods Randomized, blinded, comparative effectiveness clinical trial. Children < 18y BP...
Abstract Background Bacterial infection (BI), both community-acquired (CA-BI) and hospital-acquired (HAI), might present as a severe complication in patients with bronchiolitis. This study aimed to describe BI children bronchiolitis, define risk factors for BI. Methods was prospective, descriptive that included infants admitted the pediatric intensive care unit (PICU) due bronchiolitis between 2011 2017. The BROSJOD score calculated rate severity of Results Inclusion 675 patients, median age...
During the pandemic caused by novel coronavirus (COVID-19), lung ultrasound has been used to diagnose and monitor respiratory condition. The aim of study was describe findings in children with a COVID-19 infection. Patients younger than 18 years old positive for COVID-19, admitted pediatric tertiary referral hospital were included. They divided into two groups depending on presence symptoms. Lung results categorized four degrees according Soldati et al. score (J Ultrasound Med 39:1–7, 2020)...
Abstract Background The purpose of this paper is to describe how end-of-life care managed when life-support limitation decided in a Pediatric Intensive Care Unit and analyze the influence further development Palliative Unit. Methods A 15-year retrospective study children who died after was initiated pediatric intensive unit. Patients were divided into two groups, pre- post-palliative unit development. Epidemiological clinical data, decision-making process, approach analyzed. Data obtained...
To describe the development of an artificial placenta (AP) system in sheep with learning curve and main bottlenecks to allow survival up one week.A total 28 fetal were transferred AP at 110-115 days gestation. The goal was increased progressively three consecutive study groups: 1-3 h (n = 8), 4-24 10) 48-168 10). Duration cannulation procedure, technical complications, pH, lactate, extracorporeal circulation (EC) circuit flows, heart rate, outcomes across experiments compared.There a...
Objective Three scores have been proposed to stratify the risk of mortality for each cardiac surgical procedure: The RACHS-1, Aristotle Basic Complexity (ABC), and STS-EACTS complexity scoring model. aim was compare ability predict morbidity three applied a specific population. Design Retrospective, descriptive study. Setting Pediatric neonatal intensive care units in referral hospital. Patients Children under 18 years admitted unit after surgery. Interventions None. Outcome measures...
Objectives To assess the kinetics of procalcitonin (PCT) and C-reactive protein (CRP) in newborns after cardiothoracic surgery (CS), with without cardiopulmonary bypass, to whether PCT was better than CRP identifying sepsis first 72 hours CS. Patients Methods This is a prospective study admitted neonatal intensive care unit Interventions were sequentially drawn 2 before at 0, 12, 24, 48, surgery. Results A total 65 patients recruited, which 14 excluded because complications. We compared CS...
Cardiopulmonary bypass (CPB) generates a systemic capillary leak syndrome with pulmonary edema. Lung ultrasound (LUS) could be useful to monitor it. Primary objective was compare sensitivity, specificity, positive and negative predictive values of chest X-ray LUS detect edema using new score (LUCAS). Secondary objectives were evaluate correlation between LUCAS respiratory inotropic support.Prospective intervention study including patients <2 months admitted the Pediatric Intensive Care Unit...
Lung ultrasound (LUS) and procalcitonin (PCT) are independently used to improve accuracy when diagnosing lung infections. The aim of the study was evaluate a new algorithm combining LUS PCT for diagnosis bacterial pneumonia.Randomized, blinded, comparative effectiveness clinical trial. Children <18 years old with suspected pneumonia admitted pediatric intensive care unit were included, randomized into experimental group (EG) or control (CG) if chest X-Ray (CXR) done as first pulmonary image,...
Introduction Chimeric antigen receptor (CAR)T-cell CD19 therapy is an effective treatment for relapsed/refractory B-cell acute lymphoblastic leukemia. It can be associated with life-threatening toxicities which often require PICU admission. Purpose: to describe clinical characteristics, and outcome of these patients. Methods Prospective observational cohort study conducted in a tertiary pediatric hospital from 2016-2021. Children who received CAR-T admitted were included. We collected...
<b><i>Introduction:</i></b> Persistent pulmonary hypertension of the newborn (PPHN) is a neonatal syndrome associated with significant morbidity and mortality that caused by failure postnatal drop in vascular resistance. In extreme cases, patients may require extracorporeal membrane oxygenation therapy (ECMO). The aim this study was to explore lung ultrasound (LUS) patterns newborns PPHN requiring ECMO. <b><i>Patients Methods:</i></b> From...
Introduction and objective Children admitted to the pediatric intensive care unit after cardiovascular surgery usually require treatment with antibiotics due suspicion of infection. The aim this study was assess effectiveness procalcitonin in decreasing duration antibiotic children surgery. Methods Prospective, interventional carried out a unit. Included patients under 18 years old cardiopulmonary bypass. Two groups were compared, depending on implementation PCT-guided protocol stop or...
Lung ultrasound (LUS) is a bedside tool useful to diagnose neonatal respiratory disease and guide surfactant therapy. LUS scores have emerged as for newborn distress but unknown if support settings may influence it. The aim of the study was evaluate feasibility evaluating lung recruitment in term newborns with when noninvasive it increased.Prospective tertiary intensive care unit. Inclusion criteria were neonates requiring nasal continuous positive airway pressure (nCPAP) within first 6 h...
To develop a quantitative predictive scoring model for the early recognition and assessment of paediatric sepsis.Prospective observational study including emergency department in-hospital febrile patients under 18 years. Sepsis diagnose (Goldstein 2005 definitions) was main outcome. Variables associated with outcome were included in multivariable analysis. Cut-off points, odds ratio coefficients variables kept after analysis identified. The score obtained from coefficients, AUC ROC-analysis,...