A5100359000- Chemical Synthesis and Analysis
- Synthetic Organic Chemistry Methods
- Microbial Natural Products and Biosynthesis
- Carbohydrate Chemistry and Synthesis
- Synthesis and properties of polymers
- Organometallic Complex Synthesis and Catalysis
- Peptidase Inhibition and Analysis
- Model-Driven Software Engineering Techniques
- Metal complexes synthesis and properties
- Glycosylation and Glycoproteins Research
- HIV/AIDS drug development and treatment
- Selenium in Biological Systems
- Advanced biosensing and bioanalysis techniques
- biodegradable polymer synthesis and properties
- Polysaccharides and Plant Cell Walls
- DNA and Nucleic Acid Chemistry
- Hydrology and Drought Analysis
- Proteoglycans and glycosaminoglycans research
- Signaling Pathways in Disease
- Medicinal Plants and Bioactive Compounds
- Biochemical effects in animals
- Meteorological Phenomena and Simulations
- Plant biochemistry and biosynthesis
- Heterotopic Ossification and Related Conditions
- Click Chemistry and Applications
Beijing Normal University
2020-2025
University of Victoria
2018-2024
Nanjing University of Information Science and Technology
2024
Harbin Normal University
2023-2024
Pacific Institute for Climate Solutions
2024
Cornell University
2021
Ithaca College
2021
China Pharmaceutical University
2019
Guangdong Medical College
2016
Key Laboratory of Guangdong Province
2016
Present study further unravels the underlying mechanism of RE on lifespan <italic>C. elegans</italic>: insulin/IGF-1 signaling (IIS) and SKN-1 pathways.
Abstract Rare precipitation events with return periods of multiple decades to hundreds years are particularly damaging natural and societal systems. Projections such rare, in the future climate are, however, subject large inter‐model variations. We show that a substantial portion these differences can be ascribed projected warming uncertainty, robustly reduced by using observed during recent as an observational constraint, implemented either directly constraining projections or conditioning...
Stimuli-responsive nanocarriers for anticancer drug and gene co-delivery are a promising strategy in cancer therapy due to their combination of chemotherapy therapy. In this work, we developed facile effective method fabricate stimuli-responsive based on complexes polyethylenimine (PEI) with an adenosine triphosphate (ATP) responsive aptamer duplex (ARAD). No chemical reactions or complex modifications were used the construction processes. system, Doxorubicin-loaded plasmid DNA (p53) can be...
Polydicyclopentadiene (PDCPD) is a durable, highly cross-linked material that used industrially for the production of automotive body panels among other applications. We recently described novel C-linked, ester-functionalized polydicyclopentadiene (fPDCPD) introduces tunable surface energy and increased Tg, without sacrificing desirable thermal stability parent polymer. In this report, we describe an extensive spectroscopic study aimed at rigorous characterization structure cross-link in our...
Polydicyclopentadiene (PDCPD) is a ring-opening metathesis polymer derived from dicyclopentadiene. Valued for its light weight, excellent material strength, and good performance at both high low temperatures, PDCPD used to make body panels tractors heavy-duty trucks. We recently described the first functionalized form of (fPDCPD) that maintains thermal stability parent polymer. However, while commercial components are produced through reaction injection molding process on very large scale,...
The calcineurin/nuclear factor of activated T cell (CN/NFAT) signaling pathway plays a critical role in the immune response. Therefore, inhibition CN/NFAT is an important target for inflammatory disease. conserved PXIXIT and LXVP motifs CN substrates targeting proteins have been recognized. Based on affinity ability inhibitory effect these docking sequences CN, we designed bioactive peptide (named pep3) against interaction, which has two binding sites derived from RCAN1-PXIXIT motif...
The ester group on a functionalized form of polydicyclopentadiene (<italic>f</italic>PDCPD) was harnessed to attach several biologically relevant appendages, including fluorescent dye, an RGD peptide, and releasable antibacterial agent control<italic>E. coli</italic>growth.
Polydicyclopentadiene (PDCPD) is a thermoset polymer that valued in industry for its excellent mechanical properties, heat resistance, and chemical tolerance. However, the commercial lacks chemically tunable functionality. Recently, methyl ester functionalized polydicyclopentadiene (fPDCPD) was shown to offer significantly improved tunability while maintaining same thermal stability as unfunctionalized parent polymer. In this report, we describe synthesis characterization of poly[(methyl...
Photo-induced synthesis, stereochemistry and antitumor activity of valine-based small cyclopeptides were studied.
Lentinan is a clinically approved immune modulator and its anticancer immunomodulatory bioactivity found to be dependent on triple helical conformation. Therefore, the development of rapid convenient method for determination bioactive lentinan with conformation holds great promise quality control healthy products. In this work, an aniline blue fluorescent was optimized established accurately rapidly detect lentinan. presence lentinan, fluorescence intensity 404 nm excitation 492 emission...