A5045097672- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
- Veterinary Oncology Research
- Cancer Genomics and Diagnostics
- Cleft Lip and Palate Research
- Epigenetics and DNA Methylation
- Cancer, Lipids, and Metabolism
- Cervical Cancer and HPV Research
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Infectious Diseases and Mycology
- Cancer-related Molecular Pathways
EsSALUD
2015-2018
Abstract DDIT4 gene encodes a protein whose main action is to inhibit mTOR under stress conditions whilst several in vitro studies indicate that its expression favors cancer progression. We have previously described an independent prognostic factor for tripe negative breast resistant neoadjuvant chemotherapy. herein report high related the outcome (recurrence-free survival, time progression and overall survival) types. performed silico analysis online platforms, pooled datasets from KM...
There are different biological and clinical patterns of lung cancer between genders indicating intrinsic differences leading to increased sensitivity cigarette smoke-induced DNA damage, mutational KRAS better outcomes in women while at gene-expression levels was not previously reported. Here we show an enrichment immune genes NSCLC compared men. We found a GSEA analysis (by processes annotated from Gene Ontology) six public datasets repeated observation gene sets women. "Immune system...
Abstract INTRODUCTION: There is different susceptibility to DNA damage induced by tobacco smoking between women and men. In despite of the great advances in knowledge genomic landscape lung cancer, not explored molecular differences man women. Our aim was evaluate differentially enriched gene sets two genders. METHODS: We evaluated 03 public databases containing expression values from adenocarcinoma patients: GSE50081 (HG-U133_Plus_2; n = 181 samples), GSE47115 (Illumina HumanHT-12 WG-DASL...
e24325 Background: POLR1C is a gene encoding subunit common to RNA polymerases I and III. Currently, mutations in this are known have been associated with Treacher Collins Syndrome hypomyelinating leukodystrophy. Despite high transcriptional activity characteristic of cancer cells, only few works linked its expression some tumoral aggressiveness features. Our aim work was evaluate the relationship outcome different types malignant neoplasm. Methods: The association patients evaluated...
e24288 Background: Abnormal changes in the metabolism are cancer hallmarks and can be used as therapeutic targets. Our study aim was to identify enriched metabolic pathways patients (pts) with squamous cell lung (SQLC). Methods: We evaluated RNA-Seq data (RPKM) of Normal tissues SQLC from GTEx (n = 320) TCGA 215), respectively. Genes KEGG were manually curated. Highly stable genes normalization. Overall, 2819 a Gene Set Enrichment Analysis (GSEA). The randomly divided training 150)...