<b><i>Objective:</i></b> To assess the relative frequency of occurrence motor, perceptual, peripersonal, and personal neglect subtypes, association other related deficits (e.g., deficient nonlateralized attention, anosognosia), neuroanatomic substrates in patients with right hemisphere stroke rehabilitation settings. <b><i>Methods:</i></b> The authors assessed 166 inpatients outpatients measures motor sensory function, functional disability, family burden. Detailed lesion analyses were also...

It has been shown that unilateral left neglect can be significantly improved for a short time after period of adaptation to prismatic shift the visual field right. In neuropsychological studies, however, there is no evidence demonstrating long‐lasting effects following treatment by prism (PA). The first aim present study was find out whether short‐term amelioration found could converted into long‐term therapeutic improvement. Secondly, we investigated improvement in standard tests...

Recent fMRI evidence has detected increased medial prefrontal activation during contemplation of personal moral dilemmas compared to impersonal ones, which suggests that this cortical region plays a role in judgment. However, functional imaging results cannot definitively establish brain area is necessary for particular cognitive process. This requires from lesion techniques, such as studies human patients with focal damage. Here, we tested 7 lesions the ventromedial cortex and 12 healthy...

Humans and monkeys share similar sensory integrated processing of tactile peri-hand visual inputs for coding peripersonal space surrounding the hand. In monkeys, tool use is known to induce a transient elongation hand-centred along axis. Here we report evidence that, also in humans, can increase spatial extent representation incorporate tool. We investigated this phenomenon patients with extinction, by using cross-modal paradigm well suited reveal visual-tactile integration near patients'...

Current interpretations of extinction suggest that the disorder is due to an unbalanced competition between ipsilesional and contralesional representations space. The question addressed in this study whether left right space one sensory modality (i.e., touch) can be reduced or exacerbated by activation intact spatial representation a different functionally linked damaged vision). This hypothesis was tested 10 right-hemisphere lesioned patients who suffered from reliable tactile extinction....

In the present work, we investigated whether an auditory peripersonal space exists around hand and such a might be extended by brief tool-use experience or long-term using tool in everyday life. To this end, studied audio-tactile integration far space, blind subjects who regularly used cane to navigate sighted subjects, before after training with cane. was limited use, then expanded contracted backward resting period. contrast, peri-hand immediately when they held but short handle. These...

The hypothesis that right posterior parietal lesions cause two attentional deficits, namely, a reduced reactivity to stimuli in the left visual field (LVF), and any stimulus which occupies relative position, was tested 8 patients with an extinction syndrome. In Experiments 1 2 first by measuring reaction times (RTs) presented LVF RVF, whereas second RTs totally positioned LVF, RVF. results showed (1) occupied position were longer than independent of stimulated (2) RVF stimuli. Experiment 3...

The evolutionary pattern of spontaneous recovery from acute neglect was studied by assessing cognitive deficits and motor impairments. Detailed lesion reconstruction also performed to correlate the presence neural substrates.A consecutive series right brain-damaged (RBD) patients with without underwent weekly tests in phase illness. battery assessed deficits, neglect-related impairment. Age-matched normal subjects were investigated ascertain non lateralised attentional deficits. Some...

To investigate the long-term behavioral and neurophysiologic effects of combined time-locked repetitive transcranial magnetic stimulation (rTMS) physical therapy (PT) intervention in chronic stroke patients with mild motor disabilities.Thirty were enrolled a double-blind, randomized, single-center clinical trial. Patients received 10 daily sessions 1 Hz rTMS over intact cortex. In different groups, was either real (rTMS(R)) or sham (rTMS(S)) administered immediately before after PT. Outcome...

Abstract Converging evidence suggests that emotion processing mediated by ventromedial prefrontal cortex (vmPFC) is necessary to prevent personal moral violations. In dilemmas, for example, patients with lesions in vmPFC are more willing than normal controls approve harmful actions maximize good consequences (e.g., utilitarian judgments). Yet, none of the existing studies has measured subjects' emotional responses while they considered dilemmas. Therefore, a direct link between and judgment...

Abstract The contribution of the medial prefrontal cortex, particularly anterior cingulate cortex (ACC), to cognitive control remains controversial. Here, we examined whether rostral ACC is necessary for reactive adjustments in following occurrence response conflict [Botvinick, M. M., Braver, T. S., Barch, D. Carter, C. &amp; Cohen, J. Conflict monitoring and control. Psychological Review, 108, 624–652, 2001]. To this end, assessed 8 patients with focal lesions involving sector (rACC...

This study was conducted to investigate the effectiveness on neglect recovery of a 2-week treatment based prism adaptation (PA) in comparison an analogous visuomotor training performed without prisms, ie, neutral pointing (NP).Twenty patients were divided into 2 matched groups, one submitted PA (PA group) and other NP (NP for 10 daily sessions over period weeks. After end treatment, group also treatment. Neglect assessed before after each 1 month treatment.Visuospatial abilities improved...

Short-term memory (STM), long-term (LTM), and recency judgment were investigated in 75 right-handed nonaphasic patients without visual deficits who had epileptic foci localized one of four different regions the brain: right temporal lobe, left frontal lobe. The results led to following conclusions: (1) lesions yielded comparatively greater impairment for verbal LTM task, whereas more disruptive spatial task; (2) no significant differences between left- right-brain-damaged STM tasks obtained;...

In close analogy with neurophysiological findings in monkeys, neuropsychological studies have shown that the human brain constructs visual maps of space surrounding different body parts. right-brain-damaged patients tactile extinction, existence a peripersonal centred on hand has been demonstrated by showing cross-modal visual–tactile extinction is segregated mainly near hand. That is, stimuli contralesional are extinguished more consistently presented ipsilesional than those far from it....

In this paper different models of anosognosia are confronted and data concerning denial behaviors presented that were collected on a selected population right brain-damaged patients affected by motor neglect disorders. Anosognosia for impairment cognitive impairments found to be dissociated, as well the upper lower limb impairments. These findings then discussed in an attempt choose more suitable theoretical framework interpreting various disorders related illness.

One of the most effective techniques in rehabilitation visual field defects is based on implementation oculomotor strategies to compensate for loss. In present study we develop a new approach audio-visual stimulation field. Since it has been demonstrated that interaction multisensory neurons can improve temporally perception patients with hemianopia, aim was verify whether systematic might induce long-lasting amelioration disorders. Eight chronic were trained detect presence targets. During...