- Cutaneous Melanoma Detection and Management
- Microscopic Colitis
- Inflammatory Bowel Disease
- Central Venous Catheters and Hemodialysis
- Medicine and Dermatology Studies History
- Vascular Procedures and Complications
- Eosinophilic Esophagitis
- Diverticular Disease and Complications
- Chronic Lymphocytic Leukemia Research
- Hippo pathway signaling and YAP/TAZ
- Venous Thromboembolism Diagnosis and Management
- Digital Imaging in Medicine
- Enterobacteriaceae and Cronobacter Research
- Heme Oxygenase-1 and Carbon Monoxide
- Decision-Making and Behavioral Economics
- Gastrointestinal motility and disorders
- Gastrointestinal Tumor Research and Treatment
- Nail Diseases and Treatments
- Artificial Intelligence in Healthcare and Education
- Myofascial pain diagnosis and treatment
- Autoimmune and Inflammatory Disorders
- Smoking Behavior and Cessation
- Acupuncture Treatment Research Studies
- Cellular Mechanics and Interactions
- Porphyrin Metabolism and Disorders
Mayo Clinic in Arizona
2020-2024
Mayo Clinic
2021-2023
WinnMed
2021-2023
University of Utah
2018-2021
Huntsman Cancer Institute
2018
Abstract Background Ileal pouch–anal anastomosis (IPAA) is the standard restorative procedure following proctocolectomy in patients with inflammatory bowel disease (IBD) who require colectomy. However, removal of diseased colon does not eliminate risk pouch neoplasia. We aimed to assess incidence neoplasia IBD IPAA. Methods All at a large tertiary center International Classification Diseases–Ninth Revision/International Diseases–Tenth Revision codes for underwent IPAA and had subsequent...
Metastasis is the main cause of carcinoma-related death, yet we know little about how it initiates due to our inability visualize stochastic invasion events. Classical models suggest that cells accumulate mutations first drive formation a primary mass, and then downregulate epithelia-specific genes metastasis. Here, using transparent zebrafish epidermis model simple epithelia, can directly image invasion. We find KRas-transformation, implicated in early carcinogenesis steps, drives cell by...
Peripherally inserted central catheters (PICC) are occasionally placed in the great saphenous vein (GSV) and anterior accessory (AAGSV) patients with inadequate upper extremity veins or contraindications to placement. Outcomes on placement of PICCs these limited.This study aimed determine technical success safety GSV/AAGSV PICCs.This is a retrospective that reviewed all PICC placements between January 2011 December 2019. A total 29 procedures were identified. The electronic medical record...
Abstract Background Follicular mucinosis (FM) is a rare disease characterized by mucin accumulation in the follicular unit. FM's etiology still widely debated since its first description 1957. usually reported to be benign children, although reports of malignant transformation, most commonly mycosis fungoides, exist. The present project aims demonstrate that children with diagnosis have positive long‐term outcomes and do not develop fungoides. Materials methods This retrospective cohort...
PURPOSE Fibrin sheaths are a significant cause of dialysis catheter dysfunction. This study aimed to determine the role anticoagulation, antiplatelet medications, and other factors in delaying fibrin sheath formation. METHODS An institutional review board-approved retrospective all patients treated for tunneled from January 2014 2020 was undertaken. All catheters were symmetric tipped, 14.5 F diameter, placed via internal jugular vein. Seventy with venographically confirmed that developed...
Ibrutinib, an irreversible Bruton tyrosine kinase inhibitor, has been associated with increased risk of bleeding. There is a paucity data on the bleeding in patients ibrutinib undergoing dermatologic surgery.To determine frequency complications surgery.A retrospective, single-center, case-control study skin surgery between January 2013 and March 2020 compared sex, disease, age-matched control cutaneous surgeries.A total 75 surgeries performed 37 case 116 64 were included. Ibrutinib was...
Abstract: Background: Botanicals are increasingly incorporated into skincare products. Although allergic contact dermatitis due to botanicals is recognized, data describing the prevalence of positive patch tests sparse. Objective: To report Mayo Clinic experience testing selected botanical products in standard, extended fragrance, and plant series. Methods: IRB-approved retrospective study with from 1997 2017. Results: In total, 12,169 people were tested series; 4032 men 8137 women. The mean...
Metastasis is the predominant reason that patients succumb to cancer, yet mechanisms drive initial tumor cell invasion are poorly understood. We previously discovered crowding-induced apical extrusion drives most epithelial death, critical maintaining constant densities. Oncogenic mutations can disrupt extrusion, instead causing masses form and aberrant basal extrusion. Using transparent zebrafish epidermis model simple epithelia, we image events live at high resolution. find...
Background: Rectovaginal and anovaginal fistulizing disease (RVF) occurs in 10% of Crohn`s (CD) patients is a debilitating condition, often refractory to medical therapy. Patients with RVF have variable response treatment surgical intervention, requires long-term immunosuppressive therapy are at increased risk proctectomy. As such, our aim was describe the strategies used treat evaluate outcomes treatment. Methods: Medical records from 3 tertiary IBD centers were reviewed using informatics...
*Department of Dermatology, Mayo Clinic, Rochester, Minnesota †Mayo Clinic Alix School Medicine, The authors have indicated no significant interest with commercial supporters. For a copy the surveys, please contact author directly at [email protected].