A5016149701- Healthcare Policy and Management
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Pediatric health and respiratory diseases
- Oral health in cancer treatment
- Ion channel regulation and function
- Exercise and Physiological Responses
- Primary Care and Health Outcomes
- Heart Failure Treatment and Management
- Pharmacological Effects of Natural Compounds
- Hepatocellular Carcinoma Treatment and Prognosis
- High Altitude and Hypoxia
- Traditional Chinese Medicine Studies
- Lung Cancer Treatments and Mutations
- Clinical practice guidelines implementation
- Stroke Rehabilitation and Recovery
- Patient Satisfaction in Healthcare
- Quality and Safety in Healthcare
- Mitochondrial Function and Pathology
- Maternal and Perinatal Health Interventions
- Hospital Admissions and Outcomes
- Ginseng Biological Effects and Applications
- Global Health Care Issues
- Cleft Lip and Palate Research
- Head and Neck Cancer Studies
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Massachusetts General Hospital
2013-2024
Gansu Agricultural University
2021
Capital Medical University
2016
Association of Academic Health Centers
2013
Ling Tung University
2009
To quantify the role of teaching hospitals in direct patient care, authors compared characteristics patients served by varying intensity.The studied Medicare beneficiaries ≥ 66 years old, hospitalized 2009-2010 for acute myocardial infarction, heart failure, or pneumonia. They categorized as nonteaching, teaching, Council Teaching Hospitals and Health Systems (COTH) members performed secondary analyses using intern resident-to-bed ratios. The used descriptive statistics, adjusted odds...
128 Background: Fruquintinib is a standard third-line treatment in metastatic colorectal cancer (mCRC). However, no therapeutic regimen available for mCRC patients who progressed on therapy. Preclinical experiments supported rationale combining antiangiogenic therapy and 5-fluorouracil (5FU) refractory with evidence synergy. This open-label phase Ib/II study was designed to determine the safety efficacy of fruquintinib plus 5-fluorouracil/leucovorin monotherapy. Methods: The enrolled would...
Increasing evidence suggests that ion channels not only regulate electric signaling in excitable cells but also play important roles the development of brain tumor. However, glioma remain controversial. In present study, we systematically analyzed expression patterns channel genes a cohort Chinese patients with using RNAseq profiling. First, molecular signature comprising three (KCNN4, KCNB1 and KCNJ10) was identified Univariate Cox regression two-tailed student's t test conducted overall...
To assess the quantity and impact of research publications among US acute care hospitals; to identify hospital characteristics associated with publication volumes; estimate independent association bibliometric indicators Hospital Compare quality measures.Hospital Compare; American Association Survey; Magnet Recognition Program; Science Citation Index Expanded.In cross-sectional studies using a 40% random sample Medicare-participating hospitals, we estimated associations volumes...
Patients with metastatic pancreatic cancer typically have poor prognosis due to the limited effectiveness of existing treatment options. ALK rearrangement–positive is rare in cancer, but may occur those KRAS-wild type. We present a 34-year-old young man and who had remarkable response crizotinib after resistance prior chemotherapy re-response alectinib brain metastases developed. This clinical observation suggests that comprehensive molecular profiling guide targeted therapies not only...
Five-fluorouracil, folinic acid, oxaliplatin and irinotecan (FOLFOXIRI) regimen is used as the first-line treatment for metastatic colorectal cancer (mCRC). The use of capecitabine, an oral fluoropyrimidine pro-drug, feasible safe; hence, it provides interesting alternative to 5-fluorouracil in abovementioned regimen. This study aimed evaluate efficacy safety oxaliplatin, (XELOXIRI) with or without targeted drugs Chinese patients mCRC.We conducted a retrospective, longitudinal cohort mCRC...
Objectives To investigate the association between hospital safety culture and 30‐day risk‐adjusted mortality for Medicare patients with acute myocardial infarction ( AMI ) in a large, diverse cohort. Subjects The final analytic cohort consisted of 19,357 discharges (Med PAR data) linked to 257 AHRQ Hospital Survey on Patient Safety Culture surveys from 171 hospitals 2008 2013. Study Design Observational, cross‐sectional study using hierarchical logistic models estimate scores patient...
The public health impact of returning to school after vacations on children's asthma have not been well explored. In this study, we investigated the timing and magnitude New York State hospitalizations from 1991 2001. We used a generalized additive model assess risk associated with return among children compared adults elderly. Hospital admissions first day were days following four breaks. Exceedance both length cost hospital stay estimated. A significant increase in for (20% 300%) was each...
Background National Hospital Quality Measures (NHQM) should accurately reflect quality of care, as they increasingly impact reimbursement and reputation. However, similar to risk adjustment outcomes measures, NHQM process measures pose unique methodological concerns, including lack representativeness the final denominator population after exclusions. This study determines size characteristics for each acute myocardial infarction (AMI) measure, reasons exclusion from variation in rates among...
Intro: Stroke is a major public health burden, but few data are available on the distribution of relative inpatient stroke costs. We determined key drivers cost in patients hospitalized with ischemic (IS) to inform decisions regarding optimal resource use. Methods: linked 1,578 IS our local Get Guidelines database (2010- 2013) administrative, accounting (EPSI, inc). Relative hospital costs by department within 30 days post admission were stratified quartiles into very high (n=394), (n=395),...