A5075429563- Hydrogels: synthesis, properties, applications
- biodegradable polymer synthesis and properties
- Enzyme Catalysis and Immobilization
- Biofuel production and bioconversion
- Advanced Cellulose Research Studies
- Dendrimers and Hyperbranched Polymers
- Synthesis of Tetrazole Derivatives
- Enzyme Production and Characterization
- Polysaccharides and Plant Cell Walls
- Melanoma and MAPK Pathways
University of Trieste
2022-2025
In the quest for a bio-based and safer substitute glutaraldehyde, we have investigated 2,5 diformylfuran (DFF) as bifunctional crosslinking agent covalent immobilization of glucoamylase on amino-functionalized methacrylic resins. Immobilization experiments systematic comparison with glutaraldehyde at four different concentrations activation step showed that DFF leads to comparable enzymatic activities all tested concentrations. Continuous flow experiment confirms similar long term stability...
Infrared thermal activation (IRTA) is considered an efficient approach to accelerate reaction rates. We report the first example of application IRTA achieve surface functionalization cellulose nanocrystals (CNCs) in solvent-less conditions with epoxidized linoleic acid (ELA), synthesized by enzymatic using CaLB (lipase B from Candida antarctica) and H2O2. The final goal enhance hydrophobicity cellulosic surfaces bio-based materials, potential coating industry. extended delignified rice husk...
Two clinically approved anticancer drugs targeting BRAF in melanoma patients - dabrafenib (DAB) and vemurafenib (VEM) have been successfully encapsulated into nanomicelles formed upon self-assembly of an amphiphilic dendrimer AD based on two C18 aliphatic chains a G2 PAMAM head. The process resulted the formation well-defined (∼10 nm) core-shell (NMs) with excellent encapsulation efficiency (∼70% for DAB ∼60% VEM) good drug loading capacity (∼27% ∼24% VEM, respectively). Dynamic light...