- Advanced Statistical Process Monitoring
- Scientific Measurement and Uncertainty Evaluation
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Operations and Scheduling Optimization
- Computational Drug Discovery Methods
- Fault Detection and Control Systems
- Climate Change Policy and Economics
- Statistical Methods in Clinical Trials
- Quality and Safety in Healthcare
- Sensory Analysis and Statistical Methods
- Statistical Methods and Inference
- Monetary Policy and Economic Impact
Leiden University
2022-2024
Dynamically predicting patient survival probabilities using longitudinal measurements has become of great importance with routine data collection becoming more common. Many existing models utilize a multi-step landmarking approach for this problem, mostly due to its ease use and versatility but unfortunately most fail do so appropriately. In article we make multivariate functional principal component analysis summarize the available information, employ Cox proportional hazards model...
Summary Rapidly detecting problems in the quality of care is utmost importance for well-being patients. Without proper inspection schemes, such can go undetected years. Cumulative sum (CUSUM) charts have proven to be useful control, yet available methodology survival outcomes limited. The few continuous time usually require researcher specify an expected increase failure rate advance, thereby requiring prior knowledge about problem at hand. Misspecifying parameters lead false positive alerts...
Panel data arises when transitions between different states are interval-censored in multi-state data. The analysis of such using non-parametric models was not possible until recently, but is very desirable as it allows for more flexibility than its parametric counterparts. single available result to date has some unique drawbacks. We propose a estimator the transition intensities panel an Expectation Maximisation algorithm. method mix and right-censored (exactly observed) transitions. A...
Abstract During the past 14 years, a clinical audit has been used in Netherlands to provide hospitals with data on their performance colorectal cancer care. Continuous feedback quality of care provided at each hospital is essential improve patient outcomes. It unclear which methods should be generate most informative output for identification potential issues. Our aim compare commonly employed funnel plot existing cumulative sum (CUSUM) methodology evaluation postoperative survival and stay...
Abstract Background During the past 14 years, a clinical audit has been used in Netherlands to provide hospitals with data on their performance colorectal cancer care. Continuous feedback quality of care provided at each hospital is essential improve patient outcomes. It unclear which methods should be generate most informative output for identification potential issues. Our aim compare commonly employed funnel plot existing cumulative sum (CUSUM) methodology evaluation postoperative...