A5102934704- Drug Solubulity and Delivery Systems
- Adsorption and biosorption for pollutant removal
- Advanced Drug Delivery Systems
- Protein purification and stability
- Cannabis and Cannabinoid Research
- 3D Printing in Biomedical Research
- Crystallization and Solubility Studies
- Advancements in Transdermal Drug Delivery
- Additive Manufacturing and 3D Printing Technologies
- Analytical Methods in Pharmaceuticals
- Polymer Foaming and Composites
- Injection Molding Process and Properties
- Innovative Microfluidic and Catalytic Techniques Innovation
- Thermal and Kinetic Analysis
- Analytical Chemistry and Chromatography
- Curcumin's Biomedical Applications
- Solar-Powered Water Purification Methods
- Polymer crystallization and properties
- biodegradable polymer synthesis and properties
- Ginger and Zingiberaceae research
- Clay minerals and soil interactions
- Process Optimization and Integration
- Nanomaterials for catalytic reactions
- Flame retardant materials and properties
- Phase Equilibria and Thermodynamics
University of Mississippi
2015-2025
Minia University
2012-2024
Menoufia University
2021-2022
Mansoura University
2022
Tanta University
2021
National Research Centre
2020
National Water Research Center
2017
Zagazig University
2017
Abstract Objective The aims of the current research project were to investigate efficiency various polymers enhance solubility and increase systemic absorption piperine using hot melt extrusion technology. Methods Piperine 10–40% w/w Eudragit® EPO/Kollidon® VA 64 or Soluplus® mixed, resulting blends extruded a twin-screw extruder (Process 11, Thermo Fisher Scientific). Drug release profiles studies extrudates evaluated. A non-everted intestinal sac was employed for most promising...
Bagasse is a solid waste that remains after crushing sugarcane. Since bagasse used as fuel in sugar mills, characterization of its thermal degradation rather important order to use it efficiently. Thermal analysis was carried out using differential (DTA) and thermogravimetry (TG) under oxidizing inert atmospheres. Kinetic studies were based on weight loss obtained from TG analysis. takes place two stages: volatilization carbonization. The reaction rate, activation energy, entropy change,...
Abstract The present study aims to develop and characterize cannabidiol (CBD) solid dispersions using Vacuum Compression Molding (VCM) enhance the drug solubility release profile. Solid of CBD polymers were processed VCM at 130 °C for 4 min after a prior physical mixing. Five percent w/w was used with 5% poloxamer 188 90% polymeric carrier (Polyethylene Oxide, PEO-N80 or Hydroxypropyl cellulose, HPCEF). Discs collected milled obtain formulations (F1V, F2V). degradation temperature determined...
Low-cost bare palm branches were prepared as a sorbent for methylene blue dye from aqueous solution.The effect of reaction parameters such dose and its particle size, initial concentration the medium temperature investigated using batch sorption technique.Additionally, maximum saturated monolayer capacity was investigated.The isotherm data well-described by Freundlich equation.Based on adsorption capacity, it shown that use promising low-cost agriculture waste material dyes solutions.Kinetic...
The objective of this work was to use hot-melt extrusion (HME) technology improve the physiochemical properties lansoprazole (LNS) prepare stable enteric coated LNS tablets. For process, we chose Kollidon® 12 PF (K12) polymeric matrix. Lutrol® F 68 selected as plasticizer and magnesium oxide (MgO) alkalizer. With or without alkalizer, at 10% drug load extruded with K12 F68. changed amorphous phase showed better release compared that pure crystalline drug. Inclusion MgO improved extrudability...
Purpose: Δ9-Tetrahydrocannabinol-valine-hemisuccinate, a hydrophilic prodrug of Δ9-tetrahydrocannabinol, synthesized with the aim improving ocular bioavailability parent molecule, was investigated in lipid-based nanoparticle dosage form for delivery. Methods: Solid lipid nanoparticles (SLNs) Δ9-tetrahydrocannabinol-valine-hemisuccinate and along nanoemulsion Δ9-tetrahydrocannabinol-valine-hemisuccinate, were tested glaucoma management normotensive rabbit model by using multiple-dosing...
Objectives: The aim of the current research project was to investigate effect pressurized carbon dioxide (P-CO2) on physico-mechanical properties ketoprofen (KTP)-incorporated hydroxypropylcellulose (HPC) (Klucel™ ELF, EF, and LF) produced using hot-melt extrusion (HME) techniques assess plasticization P-CO2 various polymers tested.Methods: extrudates with without injection were examined compared addition 5% liquid plasticizer propylene glycol (PG). milled compressed into tablets. Tablet...
The aim of this study was to formulate face-cut, melt-extruded pellets, and optimize hot melt process parameters obtain maximized sphericity hardness by utilizing Soluplus® as a polymeric carrier carbamazepine (CBZ) model drug. Thermal gravimetric analysis (TGA) used detect thermal stability CBZ. Box–Behnken design for response surface methodology developed using three factors, processing temperature ( °C), feeding rate (%), screw speed (rpm), which resulted in 17 experimental runs....
Agriculture sector and food security of Egypt are under stresses due to the shortage freshwater budget. Agricultural drainage water reuse can be considered as most appropriate solution overcome irrigation shortage. Quality reused is concern, particularly in arid regions, such Egypt, salinity problems. Therefore, quality assessment for projects essential. The objective this work assess three different El-Behira Governorate, based on experimental records index approach. Thirty-six samples were...
Introduction: Cannabidiol (CBD) has sparked considerable interest because of its wide range pharmacological uses and the fact that it does not induce psychoactive effects. CBD formulation development presents significant challenges due to limited water solubility susceptibility first-pass metabolism, both which restrict overall bioavailability. The current research aimed use hot-melt extrusion (HME) technology develop mucoadhesive buccal films improve reduce metabolism. Methods: Five...