A5069442259- Anesthesia and Neurotoxicity Research
- Ocular Oncology and Treatments
- Airway Management and Intubation Techniques
- Intraocular Surgery and Lenses
- Electrolyte and hormonal disorders
- Anesthesia and Pain Management
- Methemoglobinemia and Tumor Lysis Syndrome
- Respiratory Support and Mechanisms
- Neutropenia and Cancer Infections
- Anesthesia and Sedative Agents
- Tracheal and airway disorders
- Renal and related cancers
- Neonatal Health and Biochemistry
- Retinopathy of Prematurity Studies
- Abdominal Surgery and Complications
- Ethics and Legal Issues in Pediatric Healthcare
- Ocular Infections and Treatments
- Enhanced Recovery After Surgery
- Brain Metastases and Treatment
- Free Radicals and Antioxidants
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Nanoplatforms for cancer theranostics
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Lymphoblastic Leukemia research
- Biochemical effects in animals
National Medical Research Center of Cardiology
2019-2023
Ministry of Health of the Russian Federation
2017-2022
Ministry of Health
2021
Russian Cancer Research Center NN Blokhin
2015
Background. Retinoblastoma (RB) is a life threatening cancer disease. A breakthrough in the treatment of children with RB associated improvement conservative that was administered at least one two tumor-affected eyes most bilateral cases, chemotherapy both systemic and local (selective intra-arterial intravitreal) cases combined laser therapy, cryotherapy, or brachytherapy. The development such techniques as focused on preservation visual functions, reducing number enucleations radiotherapy...
Wilms tumour (WT) (or nephroblastoma) is one of the most common malignant kidney tumors in children. On subsequent stages clinically it often characterized by abdominal hypertension syndrome, which, turn, leads to development respiratory insufficiency. Other symptoms comprise renal deficiency, hypertension, and abnormalities hemostasis hemogram. Treatment includes rounds preoperative chemotherapy surgery. We report a case perioperative management for nephrectomy 20-month-old patient with...
Treatment of children with tumors the nasal cavity and base skull is an urgent issue in both surgery anesthesiology. First all, it related to anatomical physiological characteristics children, as well localisation zone surrounded by important structures (internal carotid arteries their branches, cavernous sinus, orbit). Currently, such are removed endoscopic endonasal method. Considering anesthetic support surgeries, issues upper respiratory tract protection, correction systemic hemostasis...
Surgeries for thoracoabdominal tumors in children predispose to water and electrolyte imbalance, imbalance the coagulation system, etc. In spite of abundance recommendations children, volume basic infusion therapy is uncertain. Study purpose. To estimate clinical effectiveness conducted with isotonic balanced solution who underwent surgeries accompanied massive blood loss a complex estimation transfusion therapy. Materials methods. The intraoperative early postoperative (days 1–5) periods...
Background. Retinoblastoma is the most common intraocular malignant tumor in children. Substantial advances have been made field of local treatment, particular, through development selective intraarterial chemotherapy (SIAC). Life-threatening cardio-respiratory disorders were reported during course SIAC at moment a.ophthalmica catheterization. Objective. Our aim was to improve safety and effectiveness anesthetic management children with retinoblastoma. Methods. The retrospective study...
Caudal epidural block is the most widely used regional anesthetic technique in children. Its popularity pediatric anesthesia mainly due to its broad spectrum of indications, high success rates, and a relative low incidence complications. The caudal generally for not only lower abdominal or extremity surgery but also upper via administration adjuncts such as morphine, which has hydrosoluble potential. contraindications are presented.
Epidural administration of opioids effectively prevents the sensitization nociceptive neurons posterior horn spinal cord, induced by surgical trauma, without development motor and autonomic blockade. Study includes 52 patients aged 1 month to 18 years with malignant tumors who underwent treatment at Pediatric Oncology Hematology Research Institute, during 2009-2016 years. Surgeries were combined (thoraco-laparotomy). The method epidural use morphine in pediatric oncosurgery is presented.
Introduction. Treatment of children with mediastinal and lung tumors is an urgent problem in both surgery anesthesiology. Main goal to grant optimal conditions for the – collapse on side operation, while maintaining adequate oxygenation efficient transport oxygen tissues. The choice devices carrying out one-lung ventilation (OLV) most important factor determining safety patient. Aim study. To increase efficiency anesthesia thoracic surgeries due use bronchial blockers (BB) (OLV). Materials...
Introduction. Enhanced recovery after surgery and the early initiation of chemotherapy is a significant advantage laparoscopic surgeries for malignant tumors abdominal cavity in children. Despite extensive experience using caudal block pediatric patients, it has not yet been determined whether use ultrasound navigation provides any clinical post-operative oncology. Materials methods. The study included 40 patients Pediatric Oncology Hematology, Federal Blokhin National Medical Research...
Background. Acute tumor lysis syndrome (ATLS) complicates the treatment of highly aggressive leukemias and lymphomas in children leads to death 21.4 % severe cases. ATLS is based on cells, so volume decay products exceeds excretory capacity kidneys. The risk group includes patients with acute lymphoblastic leukemia accompanied by hyperleukocytosis (above 100 × 109/L) non-Hodgkin’s a large mass (stage III–Iv disease). development renal then multiple organ failure require intensive monitoring...
BACKGROUND: The retrobulbar block in children is used to enucleate analgesia the intra- and postoperative period prevent oculocardiac reflex (OCD), nausea, vomiting. However, when performed blindly, it results serious complications.
 AIM: This study aimed evaluate efficacy safety of a under ultrasound guidance compared with blindly during enucleation eyeball retinoblastoma.
 MATERIALS AND METHODS: A prospective randomized controlled trial was performed. included 40 patients who met...
Treatment of children with mediastinal and lung tumors is an urgent problem in both surgery anesthesiology. Main goal to grant optimal conditions for the — collapse on side operation, while maintaining adequate oxygenation efficient transport oxygen tissues. The choice devices carrying out one-lung ventilation most important factor determining safety patient. Aim. To increase efficiency anesthesia thoracic surgeries due use bronchial blockers ventilation. Materials methods. 70 were performed...
Background. The goal of treatment retinoblastoma is not only the preservation life and vision, but also minimization systemic complications, a cosmetic defect, which achieved through development selective intraarterial chemotherapy (SIACT). Repeated conduction SIACT at time catheterization a. ophtalmica accompanied by cardio-respiratory disorders (CRD). Objectives. We analyze effectiveness safety retrobulbar blockade with 0.,5 % solution ropivacaine to prevent or reduce CRD. Materials...
Aiml. Optimization of anesthesia during enucleation the eyeball in pediatric oncosurgery with an emphasis on regional methods. Material and Methods. Eight anesthesias were performed children, whose average age was 3 years, operated for retinoblastoma from July 2021 to January 2022. All patients underwent combined endotracheal anesthesia. A triple block used as a component: palatal anesthesia, infraorbital van Lint block. Results. The effectiveness adequacy proposed method using assessed...