- Clinical Nutrition and Gastroenterology
- Organ Transplantation Techniques and Outcomes
- Organ and Tissue Transplantation Research
- Renal Transplantation Outcomes and Treatments
- Vascular Procedures and Complications
- Infectious Aortic and Vascular Conditions
- Aortic aneurysm repair treatments
- Enhanced Recovery After Surgery
- Adrenal and Paraganglionic Tumors
- Anesthesia and Neurotoxicity Research
- Gastrointestinal disorders and treatments
- Liver Disease and Transplantation
- Cardiovascular Issues in Pregnancy
- Adipokines, Inflammation, and Metabolic Diseases
- Potassium and Related Disorders
- Biomedical and Chemical Research
- Biliary and Gastrointestinal Fistulas
- Protease and Inhibitor Mechanisms
- Lymphatic System and Diseases
- Methemoglobinemia and Tumor Lysis Syndrome
- Reproductive Health and Contraception
- Pediatric Hepatobiliary Diseases and Treatments
- Metabolism and Genetic Disorders
- Soft tissue tumor case studies
- Pancreatic and Hepatic Oncology Research
Institute of Clinical and Experimental Medicine
2010-2022
Charles University
2020
Centrum kardiovaskulární a transplantační chirurgie
2005-2007
University of Colorado Health
2007
Abstract Statins are widely used for the treatment of hypercholesterolemia. However, their inhibitory action on HMG‐CoA reductase also results in depletion intermediate biosynthetic products, which importantly contribute to cell proliferation. The aim present study was compare effects individual commercially available statins experimental pancreatic cancer. vitro (pravastatin, atorvastatin, simvastatin, lovastatin, cerivastatin, rosuvastatin and fluvastatin) viability human cancer were...
Kudla M operated on the patient.Chlupac J and Novotny R co-analyzed data provided consultations regarding risk of thrombosis
Introduction . Desmoid tumours (DT) are commonly associated with Gardener’s syndrome. Their surgical resection may be complicated by their close proximity to major vessels, multiple organ involvement, and frequent local recurrence. Multivisceral transplantation (MVTx) is an alternative treatment for patients intestinal liver failure. In DT closely renal structures but without end-stage kidney disease, concomitant excision of the patient’s own kidney, ex vivo tumour nephron-sparing surgery,...
Intestinal transplantation is the logical alternative to definitive total parenteral nutrition in patients with chronic intestinal failure. It has become a lifesaving procedure for failure who cannot be treated using conventional therapies. In children (over 50% of recipients) indications include short gut syndrome, primary disorders motility and mucosal diseases. adults, major indication inadaptable bowel syndrome after or subtotal resection. Patients irreversible dependency without...
An experiment was carried out on pigs during preparation of a clinical project intestinal transplantation. The objective this study to find the best surgical technique vascular and anastomosis in different experimental settings (animals with without immunosuppression) which could have major impact everyday veterinary practice. Transplantation performed 43 pigs. In part we examined most suitable anastomosis. A running continuous single-layer seromuscular suture used for all types anastomoses....
Abstract Background Pheochromocytoma is a neuroendocrine tumour originating from the chromaffin cells of adrenal glands or sympathetic paraganglia. It produces most frequently norepinephrine, epinephrine, and dopamine. As result non-specific variable clinical presentation, pheochromocytoma difficult to diagnose. Case summary A 37-year-old female without medical history 57-year-old male patient with diabetes, arterial hypertension, aortic valve replacement mechanical prosthesis were admitted...