A5070937949- Acute Lymphoblastic Leukemia research
- Childhood Cancer Survivors' Quality of Life
- Ethics and Legal Issues in Pediatric Healthcare
- Neuroblastoma Research and Treatments
- Herpesvirus Infections and Treatments
- Vascular Malformations and Hemangiomas
- Immunotherapy and Immune Responses
- Autoimmune and Inflammatory Disorders Research
- Hematological disorders and diagnostics
- Lymphoma Diagnosis and Treatment
- Renal and related cancers
- Tumors and Oncological Cases
- Vascular Tumors and Angiosarcomas
- Sarcoidosis and Beryllium Toxicity Research
- Male Breast Health Studies
- Bacterial Identification and Susceptibility Testing
- Heterotopic Ossification and Related Conditions
- Heme Oxygenase-1 and Carbon Monoxide
- Body Composition Measurement Techniques
- Liver Diseases and Immunity
- Nausea and vomiting management
- Lymphatic Disorders and Treatments
- Neutropenia and Cancer Infections
- Cell death mechanisms and regulation
- Histiocytic Disorders and Treatments
Yeditepe University
2019-2023
Yeditepe University Hospital
2020-2022
Istanbul Medeniyet University
2014-2018
Palmetto Hematology Oncology
2018
Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi
2007-2015
Ministry of Health
2007-2014
Istanbul University
2001
Aim: To standardize diagnosis and treatment of childhood Wilms tumor (WT) in Turkey. Methods patients: Between 1998 2006, WT patients were registered from 19 centers. Patients <16 years with unilateral whose started first postoperative 3 weeks included. Treatments stage I favorable (FH) unfavorable histology (UH) patients, VCR + Act-D; IIA FH, IIB Act-D radiotherapy (RT); III–IV adriamycin (ADR) RT; stages II–IV UH tumors, ADR etoposide RT. Results: 165/254 cases eligible (bilateral, 5.9%)...
In total, 74 pediatric oncology patients with hematologic malignancies (n=56) or solid tumors (n=18) and a median age of 78.5 months were included in this prospective study. The aims to assess malnutrition risks nutritional status over 6-month treatment period measured at regular intervals. rate high risk for diagnosis was 28.4% by Screening Tool Risk Impaired Nutritional Status Growth tool 36.5% Pediatric Yorkhill Malnutrition Score. Body mass index (BMI) z-scores showed 12.3%...
Transverse white nail banding can be inherited or caused by various diseases and medications, including cancer chemotherapeutic agents, retinoids, tetracyclines, antimalarials, sulfonamides, pilocarpine, cortisone zidovudine. Neither a specific drug nor classes of chemotherapeutics were associated more frequently than the other with acquired transverse leukonychia in patients cancer. Here we report four children receiving different agents.
Although varicella is a benign self-limiting disease in healthy children, it can be fatal when occurs immunocompromised hosts. Despite that immunosuppressed children are suggested to require 2 doses of vaccine achieve seroconversion, conflicting results reported the literature. The aim this study was investigate seroconversion status and mean antibody titers at first year after single dose double vaccination acute lymphoblastic leukemia patients. Patients with remission for least 1 who were...
Spontaneous remission/regression of cancer is defined as partial or complete disappearance malignant disease temporarily permanently in the absence medical treatment. This event named spontaneous regression for solid tumors and remission leukemia. The authors report case a girl aged 4 years 3 months, who presented with mediastinal mass leukemic findings bone marrow both which reappeared after remission, respectively.
Prepubertal gynecomastia due to testis tumors is a very rare condition. Nearly 5% of the patients with testicular mass present gynecomastia. Sertoli cell are sporadic in 60% reported cases, while remaining component multiple neoplasia syndromes such as Peutz-Jeghers syndrome and Carney complex. We 4-year-old boy tumor no evidence or
Background. Myeloid sarcoma is an extramedullary neoplasm of immature myeloid cells. Our study reports a presentation which presented with severe leukemoid reaction as secondary malignancy in patient who was treated for acute lymphoblastic leukemia previously. The case emphasizes the difficulties diagnosis patients do not have concomitant leukemia. Case Presentation. A 6-year-old girl previously fatigue, paleness, and hepatosplenomegaly. Peripheral blood smear bone marrow aspirate...
Malignant ovarian tumors are responsible for 2-3% of all cases precocious pseudopuberty (PP) in girls. The most common forms presenting as PP the granulosa cell (GCT). clinical and pathological features that occur frequently young girls, so-called juvenile (JGCT), differ histologically from those occurring adults. As a cause adult type (AGCT) extremely rare. We report 6 year-old girl with early breast development vaginal bleeding due to well encapsulated tumor. Microscopic resected tumor...
Chemotherapy-induced immunosuppression can lead to hepatitis B virus (HBV) reactivation in cancer patients. Both HBV carriers and individuals with serological signs of previously resolved exposure are under the risk severe liver failure during after chemotherapy. The objective this largest retrospective study was analyze consequences status children receiving A total 479 patients (273 boys 206 girls) aged 1–211 months diagnosed acute hematologic malignancies solid tumors were included study....
Trombosis is seen in children with acute lymphoblastic leukemia during or after L-asparaginase treatment.Posterior reversible encephalopathy syndrome (PRES) a complex characterized sudden hypertension, headache, nausea, vomiting, alteration the state of consciousness, vision defect and seizures.The cases related to this have been reportedly eclampsia, organ transplantation, immunsuppressive treatments, autoimmune diseases chemotherapy.Vasogenic edema occuring brain parencyhma constitues...
Wilms` tumor is the most common renal malignancy in children and fourth childhood cancer. It accounts 6-7% of all malignancies. Surgical resection an important therapy option transabdominal or transperitoneal with lymph node sampling preferred. Development chylous ascites following intraabdominal retroperitoneal pediatric age group generally results from extensive dissection, accidental ligation interruption lymphatic ducts. Diseases conditions affecting abdominal and/or nodes may cause...
Background: Lymphadenopathy is an abnormality in the size or character of lymph node. It may be a manifestation infectious and malignant diseases. Reactive lymphoid hyperplasia benign form lymphadenopathy. Cells develop numerous adaptive responses regulated by hypoxia inducible factor-1 alpha (Hif-1 alpha) against hypoxic stress.
 Purpose: Hif-1alpha play role process carcinogenesis early stage cancer. We aimed to investigate most common polymorphism Hif-1α C1772T G1790A gene...
Malign diseases may mimic rheumatoid diseases. Joint involvement and leg pain are among frequently encountered symptoms particularly in the patients with leukemia. Sometimes, however, primary tumor be asymptomatic because of metastasis. The present case, which admitted to our clinic bone joint continuing for 10 days mimicking acute fever (ARF) metastasis due thymic carcinoma was detected when investigated, presented it is a rare condition.
Infantile hemangioendothelioma is a rare tumor in the liver children under 3 years of age. It usually incidentally detected but may also occur with enlargement. Herein case neonatal infantile hepatosplenomegaly and respiratory-circulatory failure resulting monitoring presented literature.
Amac: Bu calismanin amaci cocuk Hodgkin hastaliginda hastalarin yasam suresi ve tedaviye yanitini inceleyerek sagkalimi etkileyen degiskenleri arastirmaktir Gerec Yontem: Hastanemiz Cocuk Hematoloji Onkoloji Klinigi rsquo;nde 1996 2011 yillari arasinda izlenen tedavi edilen 43 lenfoma hastasi geriye donuk olarak incelendi On sekiz yas altinda yeni tani almis 23 erkek 20 kiz hasta calismaya dahil edildi Bulgular: Ortanca dokuz yil bes ay olup bir evre I 21 II 12 III IV idi Hastalar erken...
Aim: In this case-control study, we investigated parental history and habits in children with acute lymphoblastic leukemia (ALL) aimed to find possible factors that could affect the risk of leukemia. Methods: Parents 105 treated for ALL over a period ten years our Clinic Pediatric Hematology-Oncology were questioned terms age, family history, nutritional habits, maternal supplement intake, smoking, alcohol consumption, X-ray exposure, accompanying diseases. Results compared control group...