A5017071545- Radiopharmaceutical Chemistry and Applications
- Medical Imaging Techniques and Applications
- Respiratory Support and Mechanisms
- Molecular Junctions and Nanostructures
- Peroxisome Proliferator-Activated Receptors
- Chemical Synthesis and Characterization
- Nutrition, Health and Food Behavior
- Metabolism and Genetic Disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Inorganic Chemistry and Materials
- Atomic and Subatomic Physics Research
- Immune cells in cancer
- Nuclear Physics and Applications
- Air Quality and Health Impacts
- Boron Compounds in Chemistry
- Radioactive Decay and Measurement Techniques
- HER2/EGFR in Cancer Research
- Muon and positron interactions and applications
University of Alabama at Birmingham
2021-2025
Indiana University of Pennsylvania
2001
The formation of a stable alkyl At-C bond occurs during the shipment 211At on 3-octanone-impregnated column and reactivity stripped from columns has been studied. could not be recovered 3-octanone organic phase using nitric acid or sodium hydroxide, even up to 10 15.7 M, respectively. Several reducing oxidizing agents, including hydrazine, hydroxylamine, ascorbic acid, ceric ammonium nitrate, potassium permanganate, hypochlorite, calcium hypochlorite were used promote recovery 211At. most...
Emerging data indicate an association between environmental heavy metal exposure and lung disease, including lower respiratory tract infections (LRTIs). Here, we show by single-cell RNA sequencing increase in Pparg gene expression macrophages from mice exposed to cadmium and/or infected with Streptococcus pneumoniae. However, the or infection mediated inhibitory posttranslational modification of peroxisome proliferator-activated receptor γ (PPARγ) exacerbate LRTIs. Cadmium increased ERK...
Due to their long circulation time in the blood, monoclonal antibodies (mAbs) such as trastuzumab, are usually radiolabeled with long-lived positron emitters for development of agents Positron Emission Tomography (PET) imaging. Manganese-52 (
52Mn is a promising PET radiometal with half-life of 5.6 days and an average positron energy 242 keV. Typically, chromium natural isotope abundance used as target material to produce this through the nat/52Cr(p,n)52Mn reaction. While Cr suitable material, higher purity could be produced by transitioning enriched 52Cr targets prevent co-production long-lived 54Mn (t1/2 = 312 day). Unfortunately, are not cost-effective without recycling processes in place, therefore, work aims explore routes...
Most clinical PET scans involve radiotracers labeled with <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">18</sup> F. A number of nuclides other than F have been introduced, including xmlns:xlink="http://www.w3.org/1999/xlink">68</sup> Ga-labeled PSMA, Ga- and xmlns:xlink="http://www.w3.org/1999/xlink">64</sup> Cu-DOTATATE, xmlns:xlink="http://www.w3.org/1999/xlink">89</sup> Zr-labeled antibodies or minibodies. These "non-standard" radionuclides...