A5030785026- Gout, Hyperuricemia, Uric Acid
- Rheumatoid Arthritis Research and Therapies
- Orthopedic Surgery and Rehabilitation
- Spondyloarthritis Studies and Treatments
- Peripheral Nerve Disorders
- Alkaline Phosphatase Research Studies
- Osteoarthritis Treatment and Mechanisms
- Tendon Structure and Treatment
- Bone and Joint Diseases
- Case Reports on Hematomas
- Lower Extremity Biomechanics and Pathologies
- Body Composition Measurement Techniques
- Chemotherapy-related skin toxicity
- Hip disorders and treatments
- Streptococcal Infections and Treatments
- Leptospirosis research and findings
- Medical Imaging and Pathology Studies
- Skin Diseases and Diabetes
- Nutrition and Health in Aging
- Breast Implant and Reconstruction
- Inflammatory Myopathies and Dermatomyositis
- Orthopedic Infections and Treatments
- Venous Thromboembolism Diagnosis and Management
- Musculoskeletal synovial abnormalities and treatments
- Veterinary medicine and infectious diseases
Marche Polytechnic University
2019-2024
To determine an US scanning protocol with the best accuracy for diagnosis of gout and CPPD in patients acute mono/oligo-arthritis unknown origin.Patients whom a joint aspiration at most clinically involved (target joint) was requested were consecutively enrolled. performed each patient before arthrocentesis. The different findings protocols calculated.A total 161 subjects included (32 patients, 30 99 disease-controls). had high specificity (0.92-0.96) (0.90-0.97), while sensitivity ranged...
Abstract Objective To develop the optimal US scanning protocol for diagnosis of calcium pyrophosphate crystal deposition (CPPD) disease. Methods In this cross-sectional study, consecutive patients with a crystal-proven CPPD disease, and age-, sex-matched disease controls negative synovial fluid analysis were prospectively enrolled in two Italian Institutions. Four rheumatologists, blinded to patients’ clinical details, performed examinations using standardized including 20 joints (shoulders,...
To explore the spectrum of articular and peri-articular ultrasound (US) findings at metacarpophalangeal (MCP) joints in calcium pyrophosphate (CPP) deposition disease (CPPD).Consecutive CPPD patients (chronic CPP crystal inflammatory arthritis or OA with CPPD), age- sex-matched controls RA were prospectively enrolled. Patients underwent bilateral US examination MCP joints. deposits, synovial inflammation, osteophytes, cartilage damage bone erosions recorded.Sixty (33, 55.0% 27, 45.0% chronic...
(1) Background: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, primarily characterized by pain. A significant proportion of patients report symptoms suggestive neuropathic The objectives this study were to investigate the presence an increased cross-sectional area (CSA) palmar digital nerves ultrasound in with active synovitis metacarpophalangeal joints and identify potential predictors such increase. (2) Methods: An examination clinically most affected hand (from second...
To investigate whether baseline monosodium urate (MSU) burden estimated by ultrasound (US) predicts the achievement of 2016 remission criteria for gout after 12 months.In this 12-month prospective, observational and single-center study, patients with fulfilling all domains preliminary at on urate-lowering therapy (ULT) least preceding 6 months were consecutively enrolled. The US findings indicative MSU deposits [aggregates, double contour (DC) sign, and/or tophi] identified according to...
Abstract Objectives To evaluate whether US findings indicating MSU deposits and US-detected inflammation (i.e. power Doppler signal) predict gout flares over 12 months. Methods Gout patients on urate-lowering therapy for at least the preceding 6 months were enrolled consecutively in this 12-month prospective, observational, single-centre study. A nested case–control analysis was performed. Cases participants with one flare follow-up period, while controls did not self-report any flare. The...
The aims of this study were to describe in detail the ultrasound (US)-guided procedures our daily rheumatology practice, evaluate feasibility and accuracy US-guided procedures, test efficacy disinfection protocol preventing infectious complications.This was a cross-sectional monocentric study. Information regarding patients' age, sex, body mass index, rheumatic disease, US pathological findings, aspirated and/or injected anatomical site, equipment (ie, probe type frequency), needle...
Some case reports and small series of patients with silicone breast implant (SBI) have reported the development systemic sclerosis (SSc) many years later, despite conflicting evidence this association in literature. Recently, SSc anti-RNA polymerase III antibodies positivity been associated previous implants and/or cancer, showing clinical features that differ from classic SSc, such as rapid diffuse cutaneous involvement scleroderma renal crisis (SRC). The specific autoimmune reaction is not...
Background: Only few case reports and series have analysed the efficacy of IL-1 inhibitors in treatment calcium pyrophosphate deposition disease (CPPD), reporting conflicting results. Objectives: The main aim this systematic literature review (SLR) was to summarize evidence use biological therapies CPPD. Methods: PRISMA-IPD guidelines were used for review. Published articles TNFα and/or CPPD reviewed. We performed a SLR using PubMed, Embase Cochrane databases. search resulted 83 articles; 11...
Di Battista, Jacopo MD∗; Cipolletta, Edoardo Carlo, Marco Carotti, Marina MD†; Giovagnoni, Andrea Salaffi, Fausto MD, PhD∗; Grassi, Walter PhD∗ Author Information
Background: In recent years, ultrasonography (US) has emerged as an accurate and reliable tool for the diagnosis of calcium pyrophosphate (CPP) deposition disease (CPPD) in daily practice. Previous studies analyzed diagnostic value US findings different tissues joints. However, no have investigated optimal scanning protocol CPPD at patient level. Objectives: To assess combinations OMERACT-defined upper lower limbs to select best minimal combination anatomic structures be scanned diagnosing...
Background: Rheumatoid arthritis (RA) is a chronic inflammatory that primarily affects the joints of hands, wrists, and feet. Anatomical damage (at bone, cartilage tendon level) occurs as consequence persistent synovial inflammation (1). In RA, periarticular soft tissues, including nerves, may also be involved. particular, there high prevalence neuropathic conditions such carpal tunnel syndrome (CTS) in RA patients. fact, presence changes can frequently documented by ultrasound (US) at level...