A5032454291- Bacteriophages and microbial interactions
- Plant Virus Research Studies
- Legionella and Acanthamoeba research
- Viral gastroenteritis research and epidemiology
- Toxoplasma gondii Research Studies
- Virology and Viral Diseases
- Bacillus and Francisella bacterial research
- Heme Oxygenase-1 and Carbon Monoxide
- RNA regulation and disease
- Cytomegalovirus and herpesvirus research
- Viral Infections and Vectors
- Viral Infections and Outbreaks Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Eosinophilic Disorders and Syndromes
- Respiratory viral infections research
- Microbial Community Ecology and Physiology
- Vibrio bacteria research studies
- Systemic Sclerosis and Related Diseases
- Polyomavirus and related diseases
- Mosquito-borne diseases and control
- Animal Disease Management and Epidemiology
- Parasitic Infections and Diagnostics
Universidade Federal de Minas Gerais
2013-2021
ABSTRACT Triggering the amoebal phagocytosis process is a sine qua non condition for most giant viruses to initiate their replication cycle and consequently promote progeny formation. It well known that requires recognition of particles >500 nm, meet this requirement, such as mimivirus, pandoravirus, pithovirus, mollivirus. However, in context discovery last decade, Marseillevirus marseillevirus (MsV) has drawn our attention, because despite its ability successfully replicate Acanthamoeba...
ABSTRACT Acanthamoeba polyphaga mimivirus (APMV) is a giant virus from the Mimiviridae family. It has many unusual features, such as pseudoicosahedral capsid that presents starfish shape in one of its vertices, through which ∼1.2-Mb double-stranded DNA released. also dense glycoprotein fibril layer covering not yet been functionally characterized. Here, we verified although these structures are essential for viral replication, they truly necessary adhesion to amoebae, natural host. In...
The giant viruses are the largest and most complex in virosphere. In last decade, new members have constantly been added to this group. Here, we provide an in-depth descriptive analysis of replication cycle Cedratvirus getuliensis, one known date. We tracked virion entry, early steps virus factory particles morphogenesis, during phase, observed a unique sequential organization immature particle elements, including horseshoe rectangular compartments, revealed by transverse longitudinal...
2′5′OAS are template-independent RNA polymerases with antiviral activity and important to homeostasis maintenance. Here we have developed quantitative PCR (qPCR) reactions for the detection of each individual human gene used them evaluate these levels in systemic sclerosis patients cells. The method was efficient quantification genes on cells after interferon (IFN) treatment, revealed that primary from increased basal OASL OAS2 genes. When treated, able induce all four Our hypothesis is...
Rio Negro virophage (RNV) was co-isolated with a strain of mimivirus named sambavirus, from Brazilian Amazon. We report the near complete genome sequence RNV, first isolated in Brazil. also present new microscopical data demonstrating that RNV particles have similar dimensions to described sputnik virophages.
Abstract The aim of this protocol is to describe the replication, purification, and titration mimiviruses. These viruses belong Mimiviridae family, first member which was isolated in 1992 from a cooling tower water sample collected during an outbreak pneumonia hospital Bradford, England. In recent years, several new mimiviruses have been different environmental conditions. giant are easily replicated amoeba Acanthamoeba genus, its natural host. Mimiviruses present peculiar features that make...