A5023084747- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Neonatal Respiratory Health Research
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Airway Management and Intubation Techniques
- Metaheuristic Optimization Algorithms Research
- Ferroptosis and cancer prognosis
- Antimicrobial Resistance in Staphylococcus
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced machining processes and optimization
- Diabetes Management and Research
- Adipokines, Inflammation, and Metabolic Diseases
- Acute Kidney Injury Research
- Immune cells in cancer
- Pleural and Pulmonary Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Cancer-related molecular mechanisms research
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Mechanical Circulatory Support Devices
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
Sichuan University
2017-2024
West China Hospital of Sichuan University
2019-2024
Xidian University
2021
Beijing University of Technology
2019
Abstract Background Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is one of the most life-threatening diseases in intensive care unit with high mortality and morbidity. Ferroptosis a newly discovered immune related cell death that associated various diseases. However, role immune-mediated ferroptosis ALI/ARDS has not been elucidated. Method We analyzed two Gene Expression Omnibus (GEO) datasets (GSE2411 GSE109913) extracted characteristic ferroptosis-related genes (FRGs)...
Evolutionary multitasking (EMT) with the ability to tackle multiple different tasks has attracted more and attention. The transferred knowledge among can simultaneously improve solving efficiency of all optimization problems in evolutionary process. However, if way transfer is inappropriate, negative will make a bad effect on performance EMT algorithms. It worth studying that how promote positive across tasks. In this paper, multiobjective algorithm named EMT-DAVT introduced. proposed...
The quality of heavy-duty machine tool foundations can drastically affect the operating life and working precision tool, high cost manufacture has drawn a lot attention. This article summarized research status relevant literature on characteristics, vibration isolation, foundation optimization, inspection tool-foundation system, induced influencing laws factors reviewed highlights achievements in heavy system at present, put forward some problems development directions existing system. It...
Objective: The aim of the study was to compare effects APRV and LTV ventilation on pulmonary permeability in severe ARDS. Methods: Mini Bama adult pigs were randomized into group (n = 5) 5). A ARDS animal model induced by whole lung saline lavage. Pigs ventilated monitored continuously for 48 h. Results: Compared with group, CStat significantly better (p < 0.05), PaO2/FiO2 ratio showed a trend be higher throughout period experiment group. extravascular water index vascular lower also...
To characterize the population of critically ill patients and infections treated with linezolid in intensive care unit (ICU), to evaluate clinical efficacy safety therapy.This multi-center, observational, real-world study was conducted across 52 hospitals between June 9, 2018, December 28, 2019. Patients who met following inclusion criteria were included: (1) admitted ICU, (2) any age group, (3) having a or laboratory diagnosis Gram-positive bacterial infection. Clinical categorized as...
Abstract Background Conventional Mechanical ventilation modes used for individuals suffering from acute respiratory distress syndrome have the potential to exacerbate lung injury through regional alveolar overinflation and/or repetitive collapse with shearing, known as atelectrauma. Animal studies demonstrated that airway pressure release (APRV) offers distinct advantages over conventional mechanical modes. However, methodologies implementing APRV vary widely, and findings clinical remain...
Noninvasive ventilation (NIV) is widely used for sequential extubation in patients with chronic obstructive pulmonary disease (COPD). However, NIV may cause many adverse events such as claustrophobia, facial skin compression, air leakage, bloating, and even reflux aspiration, resulting poor patient compliance/tolerance high failure rate, especially older adults who are at risk of communication difficulties consciousness disorder. High-flow nasal cannula (HFNC) oxygen therapy a new...
To study the association of glucose variability and ICU delirium patients after liver transplantation.This was a retrospective, single-center cohort study. Patients who admitted to transplantation during Aug. 2016 Dec. 2018 were enrolled. They divided into two groups accoding whether they had in ICU. Multivariate logistic regression analysis model used analyze relationship between delirium, Cochran-Armitage trend test linear blood levels incidence delirium.A total 242 enrolled, among them,...
Abstract Background Acute kidney injury (AKI) is a serve and harmful syndrome in the intensive care unit. Our previous study has shown that patients who will progress to AKI 3 stage are considered receive RRT. This aimed develop prediction model can predict whether progression 3. Methods Patients with 1/2, when they were first diagnosed Medical Information Mart for Intensive Care (MIMIC-III), included. RRT or within 72 hours of diagnosis excluded. We build two predictive models, respectively...
Extra-pulmonary multi-organ failure in patients with severe acute respiratory distress syndrome (ARDS) is a major cause of high mortality. Our purpose to assess whether airway pressure release ventilation (APRV) causes more damage than low tidal volume (LTV).Twenty one pigs were randomized into control group (n = 3), ARDS LTV 8) and APRV 7). Severe model was induced by repeated bronchial saline lavages. Pigs ventilated monitored continuously for 48 h. Respiratory data, hemodynamic serum...