- Neonatal and fetal brain pathology
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- EEG and Brain-Computer Interfaces
- Complex Systems and Time Series Analysis
- Neurological disorders and treatments
- Blind Source Separation Techniques
- Functional Brain Connectivity Studies
- ECG Monitoring and Analysis
- Neuroscience and Neural Engineering
- Neuroscience of respiration and sleep
- Neural dynamics and brain function
- Traumatic Brain Injury and Neurovascular Disturbances
- Fractal and DNA sequence analysis
- Phonocardiography and Auscultation Techniques
- Chaos control and synchronization
- Infant Development and Preterm Care
- Neonatal Respiratory Health Research
- Congenital Heart Disease Studies
- Cardiac Arrest and Resuscitation
- Nonlinear Dynamics and Pattern Formation
- Optical Imaging and Spectroscopy Techniques
- Neuroscience and Music Perception
- Transcranial Magnetic Stimulation Studies
- Genetic Neurodegenerative Diseases
George Washington University
2014-2024
Children's National
2015-2024
National Hospital
2024
Semmelweis University
2024
University of Arkansas for Medical Sciences
2008-2019
RELX Group (United States)
2018
Society for Maternal-Fetal Medicine
2016
Kiel University
2004-2009
University of Arkansas at Little Rock
2006-2009
Clinical Research Center Kiel
2007
Conflicting results on the existence of tremor-related cortical activity in essential tremor (ET) have raised questions role cortex generation. Here we attempt to address these issues. We recorded 64 channel surface EEGs and EMGs from forearm muscles 15 patients with definite ET. EEG EMG power spectra, relative rhythmic activity, at frequency, EEG-EMG EEG-EEG coherence were calculated their dynamics over time explored. Corticomuscular delay was studied using a new method for narrow-band...
Impaired cerebral autoregulation may contribute to secondary injury in newborns with hypoxic-ischemic encephalopathy (HIE). Continuous, noninvasive assessment of pressure can be achieved bedside near-infrared spectroscopy (NIRS) and systemic mean arterial blood (MAP) monitoring. This study aimed evaluate whether impaired measured by NIRS-MAP monitoring during therapeutic hypothermia rewarming relates outcome 36 HIE. Spectral coherence analysis between NIRS MAP was used quantify changes the...
Dynamic modulations of large-scale network activity and synchronization are inherent to a broad spectrum cognitive processes disturbed in neuropsychiatric conditions including Parkinson's disease. Here, we set out address the motor disease its modulation with subthalamic stimulation. To this end, 20 patients idiopathic nucleus stimulation were analysed on externally cued right hand finger movements 1.5-s interstimulus interval. Simultaneous recordings obtained from electromyography...
We test the scaling performance of seven leading global climate models by using detrended fluctuation analysis. analyze temperature records six representative sites around globe simulated models, for two different scenarios: (i) with greenhouse gas forcing only and (ii) plus aerosol forcing. find that both scenarios fail to reproduce universal behavior observed display wide differences. The deviations from are more pronounced in first scenario, where also trends clearly overestimated.
The question whether the human cardiac system is chaotic or not has been an open one. Recent results in chaos theory have shown that usual methods, such as saturation of correlation dimension D(2) existence positive Lyapunov exponent, alone do provide sufficient evidence to confirm presence deterministic experimental system. surrogate data analysis together with short-term prediction can be used check a given time series consistent hypothesis chaos. In this work nonlinear dynamical tools...
The pathophysiologic mechanism underlying psychogenic tremor is not clear. Continuous voluntary production of may be uncovered by a positive entrainment in different limbs. But some patients have ongoing during their waking time which unlikely to produced voluntarily. Therefore, nonvoluntary physiologic oscillatory mechanisms must considered.Fifteen with manifesting both hands, who were diagnosed using established criteria, examined. Postural was recorded accelerometry and electromyography...
Using detrended fluctuation analysis (DFA), we study long-term correlations in wind speed data. We find that not only the data themselves but also their volatilities possess long-range correlations, expressed by exponent α being larger than one half. perform a multifractal analysis. Whereas most sets show broad spectrum, recordings of two days, obtained at same measurement site, are essentially monofractal. By surrogate analysis, confirm monofractal nature these Our shows correlated...
In this paper we introduce an adaptive rule based QRS detection algorithm using the Hilbert transform (adHQRS) for fetal magnetocardiography processing. is used to combine multiple channel measurements and decision process eliminate spurious beats. The has been tested with a large number of datasets promising results were obtained.
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> Fetal magnetocardiography provides reliable signals of the fetal heart dynamics with high temporal resolution that can be used in a clinical setting. We present robust Hilbert transform method for extraction rate. Our may applied to derived from single channel or an array channels. In case multichannel data, channels combined improve signal-to-noise ratio data. The is inherently insensitive...
We performed detrended fluctuation analysis (DFA) of cardiac beat-to-beat intervals (RRis) collected from sick newborn infants over 1–4 day periods. calculated four different metrics the DFA function: exponents (>40 beats up to one-fourth record length), (15–30 beats), root-mean-square (RMS) on a short-time scale (20–50 and RMS long-time (110–150 beats). Except , all clearly distinguished two groups (favourable vs. adverse) with well-characterized outcomes. However, fluctuations more...
The objective of this study was to quantify the number segments that have contractile activity and determine propagation speed from uterine electrophysiological signals recorded over abdomen. magnetomyographic (MMG) were with a 151 channel SARA (SQUID Array for Reproductive Assessment) system 36 pregnant women between 37 40 weeks gestational age. MMG scored classified based on presence burst activity. sensor space then split into four quadrants in each quadrant signal strength at sample...
The objective was to examine the discriminatory ability of electroencephalogram (EEG) delta power in neonates with hypoxic-ischemic encephalopathy (HIE) well-defined outcomes. Prolonged continuous EEG recordings from term HIE during therapeutic hypothermia enrolled a prospective observational study were examined. Adverse outcome defined as death or severe brain injury by magnetic resonance imaging (MRI); favorable normal mild MRI. Neonates stratified Sarnat grade at admission. partitioned...