Tyler W. LeBaron

ORCID: 0000-0001-9164-6728
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About
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Research Areas
  • Hydrogen's biological and therapeutic effects
  • Biochemical effects in animals
  • Anesthesia and Neurotoxicity Research
  • Dietary Effects on Health
  • Hydrogen Storage and Materials
  • Medical and Biological Ozone Research
  • Advanced Chemical Sensor Technologies
  • Chemical Reactions and Isotopes
  • Sulfur Compounds in Biology
  • Neuroscience of respiration and sleep
  • Long-Term Effects of COVID-19
  • Diet and metabolism studies
  • Electrocatalysts for Energy Conversion
  • Cardiovascular and exercise physiology
  • Advanced battery technologies research
  • COVID-19 and Mental Health
  • Exercise and Physiological Responses
  • Eicosanoids and Hypertension Pharmacology
  • Sleep and related disorders
  • Health and Wellbeing Research
  • Pharmacology and Obesity Treatment
  • Hybrid Renewable Energy Systems
  • Various Chemistry Research Topics
  • Odor and Emission Control Technologies
  • Artificial Intelligence in Healthcare and Education

Southern Utah University
2019-2025

Slovak Academy of Sciences
2018-2023

Centre of Experimental Medicine of the Slovak Academy of Sciences
2018-2023

Comenius University Bratislava
2021-2023

Art Research Centre of the Slovak Academy of Sciences
2020

Brigham Young University - Idaho
2014

Despite the progress in management of pandemic caused by COVID-19, it is necessary to continue exploring and explaining how this situation affected athlete population around world improve their circumstances reduce negative impact changes lifestyle conditions that were necessitated due pandemic. The aim study was analyze moderating influence physical activity (PA) dietary habits on COVID-19 experience sleep quality elite amateur athletes.A total 1,420 (40.1%) (59.9%) athletes (41% women; 59%...

10.3389/fnut.2023.1143340 article EN cc-by Frontiers in Nutrition 2023-04-13

Metabolic syndrome is associated with several medical risk factors including dyslipidemia, hyperglycemia, and obesity, which has become a worldwide pandemic. The sequelae of this condition increase the cardiovascular neurological disease increased mortality. Its pathophysiology redox dysregulation, excessive inflammation, perturbation cellular homeostasis. Molecular hydrogen (H2) may attenuate oxidative stress, improve function, reduce chronic inflammation. Pre-clinical clinical studies have...

10.2147/dmso.s240122 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2020-03-01

There are many situations of excessive production reactive oxygen species (ROS) such as radiation, ischemia/reperfusion (I/R), and inflammation. ROS contribute to arises from numerous cellular pathologies, diseases, aging. can cause direct deleterious effects by damaging proteins, lipids, nucleic acids well exert detrimental on several cell signaling pathways. However, important in functions. The injurious effect hypothetically be mitigated exogenous antioxidants, but clinically this...

10.2174/1381612826666200821114016 article EN Current Pharmaceutical Design 2020-08-26

Although several studies have shown that the Coronavirus Disease 2019 (COVID-19) lockdown has had negative impacts on mental health and eating behaviors among general population athletes, few examined long-term effects elite sub-elite athletes. The present study aimed to investigate impact of COVID-19 in versus athletes two years into pandemic. A cross-sectional comparative was conducted between March April 2022, involving from 14 countries, using a convenient non-probabilistic snowball...

10.1186/s40798-023-00653-w article EN cc-by Sports Medicine - Open 2023-11-08

Abstract Background Premenstrual syndrome (PMS) consists of psychiatric or somatic symptoms negatively affecting the daily life. PMS treatment can involve use complementary-alternative approaches. Hydrogen-rich water (HRW) has antioxidant and anti-inflammatory properties that may treat PMS. This study aimed to investigate effect drinking HRW on severity premenstrual quality life women who suffer from Methods is a randomized controlled trial. Participants were into two groups (intervention...

10.1186/s12905-024-03029-8 article EN cc-by BMC Women s Health 2024-03-26

Acute physical exercise increases reactive oxygen species in skeletal muscle, leading to tissue damage and fatigue. Molecular hydrogen (H 2 ) acts as a therapeutic antioxidant directly or indirectly by inducing antioxidative enzymes. Here, we examined the effects of drinking H water -infused water) on psychometric fatigue endurance capacity randomized, double-blind, placebo-controlled fashion. In Experiment 1, all participants drank only placebo first cycle ergometer session, for comparison...

10.1139/cjpp-2019-0059 article EN Canadian Journal of Physiology and Pharmacology 2019-06-28

Hyposmia is one of the earliest and most common symptoms in Parkinson's disease (PD). The benefits hydrogen water on motor deficits have been reported animal PD models patients, but effects gas patients not studied. We evaluated effect inhalation olfactory function, non-motor symptoms, activities daily living, urinary 8-hydroxy-2'-deoxyguanine (8-OHdG) levels by a randomized, double-blinded, placebo-controlled, crossover trial with an 8-week washout period 20 PD. Patients inhaled either...

10.4103/2045-9912.248264 article EN Medical Gas Research 2018-01-01

Non-alcoholic fatty liver disease (NAFLD) is a pathology affecting around 25% of the population worldwide. Excess oxidative stress, inflammation and aberrant cellular signaling can lead to this hepatic dysfunction eventual carcinoma. Molecular hydrogen has been recognized for its selective antioxidant properties ability attenuate regulate function. We administered hydrogen-rich water (HRW) 30 subjects with NAFLD in randomized, double-blinded, placebo-controlled manner eight weeks....

10.3390/antiox11101935 article EN cc-by Antioxidants 2022-09-28

Over 2000 publications including more than 100 human studies seem to indicate that humans have only recently benefited from or known about the medical effects of H2 within past 15 years. However, we unknowingly since dawn time, H2-producing bacteria use naturally occurring hydrogen-rich waters. Moreover, first writings on therapeutic date around 1793. Since then, papers appeared sporadically in literature every few decades but never exploded until Ohsawa et al. again demonstrated hydrogen’s...

10.3390/oxygen3010011 article EN cc-by Oxygen 2023-03-14

Background: The aim of this study was to investigate the relationship between postprandial glycemic levels based on flashmonitoring and production intestinal hydrogen (H2) methane (CH4) gases measurement amount these in exhaled air. Materials Methods: We studied 14 subjects with type 2 diabetes mellitus (T2DM) individuals without (control) two food load tests, including types dietary fiber (inulin guar gum), simultaneous determination air assessment glucose levels. Results: All control group...

10.3390/nu17050917 article EN Nutrients 2025-03-06

ABSTRACT Objectives This study investigated the impact of drinking hydrogen‐rich water (HRW) on growth performance, organ weights, thiol/disulphide homeostasis, oxidative status and some hormonal, histopathological immunohistochemical changes in rats fed a restricted housing environment. Methods The eight groups (each group [male/female] rats) comprised two control, hydrogen, stress + hydrogen. All animals were given feed ad libitum for 3 months. Control HRW calculated according to weight...

10.1002/vms3.70305 article EN cc-by Veterinary Medicine and Science 2025-03-01

The inability to successfully adapt stress produces pathological changes that can lead depression. Molecular hydrogen has anti-oxidative and anti-inflammatory activities neuroprotective effects. However, the potential role of molecular in stress-related disorders is still poorly understood. present study aims investigate effects gas on resilience mice. results showed repeated inhalation hydrogen-oxygen mixed [67%:33% (V/V)] significantly decreased both acute chronic stress-induced...

10.1038/s41598-017-10362-6 article EN cc-by Scientific Reports 2017-08-22

Clinical studies have reported hydrogen-rich water (HRW) to therapeutic and ergogenic effects. The aim of this study was determine the effect acute supplementation with HRW on exercise performance as measured by VO2, respiratory exchange ratio (RER), heart rate (HR), (RR).Baseline levels all indices were determined in nineteen (4 female, 23.4 ± 9.1 yr; 15 male, 30.5 6.8 yr) healthy subjects using a graded treadmill test exhaustion. Each subject examined two additional times randomized...

10.15280/jlm.2019.9.1.36 article EN Journal of Lifestyle Medicine 2019-01-31

Glioblastoma (GBM) is the most common type of primary malignant brain tumor. Molecular hydrogen has been considered a preventive and therapeutic medical gas in many diseases including cancer. In our study, we sought to assess potential role molecular on GBM. The vivo studies were performed using rat orthotopic glioma model mouse subcutaneous xenograft model. Animals inhaled (67%) 1 h two times per day. MR imaging determine tumor volume. Immunohistochemistry (IHC), immunofluorescence...

10.1186/s13287-019-1241-x article EN cc-by Stem Cell Research & Therapy 2019-05-21

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in world. Tumor removal remains preferred frontline treatment; however, effective non-surgical interventions remain a high priority. 5-fluorouracil (5-FU) widely used chemotherapy agent, and molecular hydrogen (H

10.4251/wjgo.v14.i1.242 article EN World Journal of Gastrointestinal Oncology 2022-01-10
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