A5100406914- Catalytic Processes in Materials Science
- Catalysis and Oxidation Reactions
- Immune Response and Inflammation
- NF-κB Signaling Pathways
- Catalysts for Methane Reforming
- Advanced Chemical Physics Studies
- Natural product bioactivities and synthesis
- Industrial Gas Emission Control
- Catalysis and Hydrodesulfurization Studies
University of South Carolina
2011-2017
Blockade of excessive Toll-like receptor (TLR) signaling is a therapeutic approach being actively pursued for many inflammatory diseases. Here we report Chinese herb-derived compound, sparstolonin B (SsnB), which selectively blocks TLR2- and TLR4-mediated signaling. SsnB was isolated from herb, Spaganium stoloniferum; its structure determined by NMR spectroscopy x-ray crystallography. effectively inhibited cytokine expression in mouse macrophages induced lipopolysaccharide (LPS, TLR4...
<italic>In situ</italic> X-ray absorption fine structure (XAS) and diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) experiments were performed to elucidate the effect of Pd local on low temperature CO oxidation activity Pd/CeO<sub>2</sub> Pd/MnO<sub>x</sub>–CeO<sub>2</sub>.