Patrick Didier

ORCID: 0000-0001-9303-8152
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About
Contact & Profiles
Research Areas
  • French Historical and Cultural Studies
  • Historical Studies and Socio-cultural Analysis
  • French Urban and Social Studies
  • Enzyme Structure and Function
  • Wine Industry and Tourism
  • Peptidase Inhibition and Analysis
  • Physical education and sports games research
  • Protein Kinase Regulation and GTPase Signaling
  • Sport and Mega-Event Impacts
  • Historical and Literary Studies
  • Martial Arts: Techniques, Psychology, and Education

KRAS genes belong to the most frequently mutated family of oncogenes in cancer. The G12C mutation, found a third lung, half colorectal and pancreatic cancer cases, is believed be responsible for substantial number deaths. For 30 years, has been subject extensive drug-targeting efforts aimed at targeting protein itself, but also its post-translational modifications, membrane localization, protein-protein interactions downstream signalling pathways. So far, strategies have failed, there are no...

10.1080/21541248.2021.1979360 article EN other-oa Small GTPases 2021-09-24
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