A5066311846- Platelet Disorders and Treatments
- Blood groups and transfusion
- Chronic Lymphocytic Leukemia Research
- Autoimmune Bullous Skin Diseases
- Blood properties and coagulation
- COVID-19 Clinical Research Studies
- Atrial Fibrillation Management and Outcomes
- Pharmacogenetics and Drug Metabolism
- Liver Disease Diagnosis and Treatment
- Blood transfusion and management
- Blood donation and transfusion practices
- Venous Thromboembolism Diagnosis and Management
- Hepatitis C virus research
- Health Systems, Economic Evaluations, Quality of Life
- Acute Myeloid Leukemia Research
- Hemoglobinopathies and Related Disorders
- SARS-CoV-2 and COVID-19 Research
- Blood Coagulation and Thrombosis Mechanisms
- Erythrocyte Function and Pathophysiology
- Eicosanoids and Hypertension Pharmacology
- Hepatitis B Virus Studies
- Folate and B Vitamins Research
- Blood Pressure and Hypertension Studies
- Long-Term Effects of COVID-19
- Lipid metabolism and disorders
Humanity & Health
2019-2024
University of Macau
2014-2023
Chinese PLA General Hospital
2021
Macau University of Science and Technology
2013-2020
Chinese University of Hong Kong
2002-2012
Prince of Wales Hospital
1998-2012
Chongqing Medical University
2012
The Affiliated Yongchuan Hospital of Chongqing Medical University
2012
University of Hong Kong
1992-2008
Queen Mary Hospital
1992-2008
The pathogenesis of chronic idiopathic thrombocytopenic purpura (ITP) involves antibody-mediated platelet destruction and reduced production. Stimulation production may be an effective treatment for this disorder.We conducted a trial in which 118 adults with ITP counts less than 30,000 per cubic millimeter who had relapses or whose count was refractory to at least one standard were randomly assigned receive the oral thrombopoietin-receptor agonist eltrombopag (30, 50, 75 mg daily) placebo....
Abstract Background We aimed to clarify high-risk factors for coronavirus disease 2019 (COVID-19) with multivariate analysis and establish a predictive model of progression help clinicians better choose therapeutic strategy. Methods All consecutive patients COVID-19 admitted Fuyang Second People’s Hospital or the Fifth Medical Center Chinese PLA General between 20 January 22 February 2020 were enrolled their clinical data retrospectively collected. Multivariate Cox regression was used...
The role of high-dose dexamethasone in the treatment immune thrombocytopenic purpura adults is controversial. We assessed effectiveness as initial a series consecutive with purpura.
To evaluate patients' knowledge of warfarin and its relationship to anticoagulation control.From January March 1999, 122 patients attending the clinic Prince Wales Hospital in Hong Kong were interviewed. Their therapy adherence medical advice tested by 9 questions. A score (maximum 1.0) was calculated for each patient. The number international normalized ratios (INRs) that within target range 4 most recent visits noted.Fifty-six men 66 women participated study (mean +/- SD age 58.0 13.0,...
Objective To evaluate the association of VKORC1 genetic variants with warfarin dose requirements in a Hong Kong Chinese patient population. Methods A retrospective study patients chronically maintained on was conducted. Single nucleotide polymorphisms (SNPs) and CYP2C9 were genotyped. Stable data retrieved from medical records. Results Sixty-nine included analysis. haplotypes H1 (group A) H7 B) most common, accounting for 86% 13% all haplotypic variation this cohort. Patients carrying at...
Annually, around 850 liver transplantation is performed in Beijing, China. Recently, the new coronavirus pneumonia (COVID-19) caused by 2019 novel (2019-nCoV) has affected nearly 200 countries worldwide. 2019-nCov can cause severe lung disease, multiple-organ damage, and significant mortalities. Liver transplant recipients, because of long-term oral immunosuppressant effects, may be more susceptible to 2019-nCoV infection have a worse prognosis than general population. It urgent set up...
Aim To examine the optimal range of International Normalized Ratio (INR) for Chinese patients receiving warfarin moderate‐intensity anticoagulation. Methods This was a retrospective cohort study conducted at ambulatory setting 1400‐bed public teaching hospital in Hong Kong. The INR measurements and occurrence serious or life‐threatening haemorrhagic thromboembolic events among newly started on from 1 January 1999 to 30 June 2001 indications with target 2–3 were analysed. INR‐specific...
Cytokine storm has been reported in patients with coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. We examine the incidence of on chronic liver failure (ACLF) COVID-19 pre-existing compensated (CLD).From 20 Jan 2020 7 Feb 2020, we studied 140 consecutive admitted either Fuyang Second People's Hospital (FYSPH), Anhui or Fifth Medical Center Chinese PLA General (PLAGH) Beijing, China. Pre-existing CLD includes those cirrhosis...
In Asia–Pacific region, hepatocellular carcinoma is a serious health threat attributing to over 600,000 deaths each year and account for 70% of global cases. Clinically, the major unmet needs are recurrence after curative-intent surgery, liver transplantation or local ablation disease progression in those with not eligible resection failed locoregional therapy. recent few years, new targeted therapy immune-checkpoint inhibitors have been registered as systemic address these issues. Notably,...
Activated charcoal was prepared by the pyrolysis of coffee ground waste residues impregnated phosphoric acid and potassium hydroxide at 600 °C. In our study, spent collected from university canteen activated with gave highest surface area 708.1 ± 0.1 m2 g−1, which determined using methylene blue adsorption method. The characterized scanning electron microscopy Fourier transform infrared spectroscopy. order to ensure that produced is bio-safe, all samples were tested for possible toxic...
Aim To compare the treatment outcomes of a clinical pharmacist‐managed anticoagulation service with physician‐managed in Chinese patients. Methods A prospective, randomized trial was conducted at clinic teaching hospital Hong Kong. Patients aged ≥ 18 years who would required warfarin therapy for least 3 months were recruited. to or group. Primary outcome assessed by percentage patient time spent within target international normalized ratio (INR) range. The incidence major thromboembolic...