A5001121263- Molecular Biology Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Ultrasound and Hyperthermia Applications
- Autophagy in Disease and Therapy
- Peroxisome Proliferator-Activated Receptors
- FOXO transcription factor regulation
- RNA Research and Splicing
- Eicosanoids and Hypertension Pharmacology
- Congenital Heart Disease Studies
- E-commerce and Technology Innovations
- Genetics and Neurodevelopmental Disorders
- Sirtuins and Resveratrol in Medicine
- Mechanical Circulatory Support Devices
- Alkaloids: synthesis and pharmacology
- Atrial Fibrillation Management and Outcomes
- Coronary Artery Anomalies
- Nuclear Receptors and Signaling
- Intracerebral and Subarachnoid Hemorrhage Research
- Animal Genetics and Reproduction
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Pharmacological Effects of Natural Compounds
- Vascular anomalies and interventions
- Plant-based Medicinal Research
Wannan Medical College
2024
Beijing Anzhen Hospital
2010-2023
Capital Medical University
2010-2023
Shandong First Medical University
2000
Autophagy is promoted as a response to such environmental stress conditions ATP depletion and excessive accumulation of reactive oxygen species (ROS). Multiple signalling pathways, including AMP-activated protein kinase (AMPK), are indicated promote autophagy in ischaemic/hypoxic (I/R) heart. However, it's far more clarify the orchestrated cross-talk between AMPK other pathways autophagy. In present study, we investigated induction by hypoxia Rat H9C2 cardiomyocytes with LC3-EGFP reporter,...
To explore short-term changes after left bundle branch pacing (LBBP) using echocardiography and computed tomography (CT), especially for postoperative ventricular septal perforation.Between January September 2019, 33 patients with atrioventricular block underwent LBBP at Beijing Anzhen Hospital. All the were evaluated electrocardiography, pacing, parameters echocardiographic measurements, including major complications, during 1, 3, 6, 12 24-month follow-up. Interval perforations examined a...
To observe the influence of peroxisome proliferator-activator receptor-G (PPAR-G) gene and cytochrome P4501A1 (CYP1A1) single-nucleotide polymorphisms (SNPs), interactions among several SNPs on coronary artery disease (CAD) risk.A total 1106 participants (including 583 males 523 females) including 550 CAD patients 556 control subjects were recruited in this study, mean age for these was 55.5 ± 11.8 years old. Logistic regression used to association SNP within PPARG CYP1A1 with risk GMDR...
To construct and validate a predictive model for the risk of cerebrogenic multiple organ dysfunction syndrome (CMODS) in patients with acute cerebral hemorrhage.
Background: We have compared the patient characteristics and safety efficacy results of Micra transcatheter pacemaker from China Transcatheter Pacing Study with those global trials. Subjects Methods: In this prospective, multicenter, single-arm study, patients a class I or II guideline recommendation for single-chamber therapy were enrolled seven centers in between July 30, 2018, December 12, 2018. The primary outcome measure study was freedom system- procedure-related major complications...
Objective To investigate the effect of different antiplatelet or anticoagulation therapy on postoperative pocket hematoma after electrophysiological devices placements (EPD). Methods The selected patients were taking anti-platelet and needed implanted permanent pacemaker, cardiac resynchronization implantable cardioversion defibrillator in our Beijing Anzhen hospital from January 2010 to 2013. According type therapy, divided into 4 groups: dual (DAP, aspirin clopidogrel) group,...
Abstract Background Congenitally corrected transposition of the great arteries (ccTGA) is a rare cardiac anomaly and can lead to abnormal electrical activity heart. The implant pacemaker in such patients more complicated than conventional operations. This case report an adult with ccTGA who had leadless will provide reference for diagnosing treating patients. Case presentation A 50-year-old male patient was admitted hospital having experienced intermittent vision loss month. An...
Objective To explore whether ultrasound-mediated microbubbles destruction could enhance anti-sense RNA transfection and expression. Methods Phospholamban antisense eukaryon vector PcDNA 4. 1-asPLB was successfully constructed it transfected into cardiac myocytes by various methods including calcium phosphate precipitation, ultrasound exposure destruction. The expression of PLB sarcoplasmic retculum Ca2+ ATPase (SERCA2a) in tested RT-PCR western blot. Results increased significantly cells...
Objective To summarize the nursing experience for 6 patients receiving wireless pacemaker implantation. Methods The who received implantation first time in Beijing Anzhen Hospital, Capital Medical University from August to October 2018. The highlights included preoperative nursing, operative postoperative monitoring, follow-up and education. Results 2 of sustained atrial fibrillation combined with long pause, 4 atrionector lesion incidental pause. threshold value perception...
Left Ventricular hypertrophy (LVH) is a common complication of essential hypertension (EH). Substance P (SP) protective substance myocardium. The purposes this study were to explore the relationship between plasma SP and EH with LVH (EH-LVH) effect promoting blood circulation eliminating phlegm (PBCEP) on EH-LVH. group consisted 30 patients 20 normotensive control subjects. Patients divided into two groups: 15 without (EH-NLVH). EH-LVH not treated by antihypertensive drugs weeks before test....