María Clara Yépez

ORCID: 0000-0001-9355-5758
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About
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Global Cancer Incidence and Screening
  • Gastric Cancer Management and Outcomes
  • Gastroesophageal reflux and treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Galectins and Cancer Biology
  • Gastrointestinal motility and disorders
  • Ophthalmology and Eye Disorders
  • Gastrointestinal disorders and treatments
  • Cervical Cancer and HPV Research
  • Eosinophilic Esophagitis
  • Medical Coding and Health Information
  • Facial Nerve Paralysis Treatment and Research
  • Cancer Risks and Factors
  • Health, Environment, Cognitive Aging
  • Magnesium in Health and Disease
  • Selenium in Biological Systems
  • Economic and Financial Impacts of Cancer
  • Comparative constitutional jurisprudence studies
  • Acute Lymphoblastic Leukemia research
  • Ovarian cancer diagnosis and treatment
  • Women's cancer prevention and management
  • Gut microbiota and health
  • Social Issues and Policies in Latin America
  • Obesity, Physical Activity, Diet

University of Nariño
2004-2024

Universidad San Francisco de Quito
2015-2021

Rutgers New Jersey Medical School
1996

Rutgers, The State University of New Jersey
1996

Objective To evaluate the long-term effect of cumulative time exposed to Helicobacter pylori infection on progression gastric lesions. Design 795 adults with precancerous lesions were randomised receive anti- H. treatment at baseline. Gastric biopsies obtained baseline and 3, 6, 12 16 years. A total 456 individuals attended 16-year visit. Cumulative exposure was calculated as number years infected during follow-up. Multivariable logistic regression models used estimate risk a more advanced...

10.1136/gutjnl-2016-311685 article EN Gut 2017-06-24

Obesity is growing at an alarming rate in Latin America. Lifestyle behaviours such as physical activity and dietary intake have been largely associated with obesity many countries; however studies that combine nutrition assessment representative samples of American countries are lacking. The aim this study to present the design rationale Study Nutrition Health/Estudio Latinoamericano de Nutrición y Salud (ELANS) a particular focus on its quality control procedures recruitment processes....

10.1186/s12889-016-2765-y article EN cc-by BMC Public Health 2015-12-01

Abstract Inhabitants of Túquerres in the Colombian Andes have a 25-fold higher risk gastric cancer than inhabitants coastal town Tumaco, despite similar H. pylori prevalences. The microbiota was recently shown animal models to accelerate development -induced precancerous lesions. 20 individuals from each town, matched for age and sex, were selected analyses performed by deep sequencing amplified 16S rDNA. In parallel, status, carriage cag pathogenicity island assignment phylogeographic...

10.1038/srep18594 article EN cc-by Scientific Reports 2016-01-05

Helicobacter pylori infection is usually acquired in childhood, but little known about its natural history asymptomatic children, primarily due to the paucity of non-invasive diagnostic methods. H. strains harboring cagA and specific alleles hopQ vacA are associated with increased risk for gastric cancer. Many studies virulence markers children have bias that symptomatic subjects selected endoscopy, these may harbor most virulent strains. Our aim genotype cagA, hopQ, stool DNA samples...

10.1111/j.1523-5378.2011.00919.x article EN Helicobacter 2012-03-08

Helicobacter pylori infection affects about half of the world's population and is usually acquired in childhood. The has been associated with chronic gastritis, peptic ulcer, stomach cancer adulthood. Little known, however, its consequences on child health. We examined effect H. growth among school-age children Colombian Andes by comparing velocity presence absence infection.Children who were 4-8 years old 2004 followed up a community where infected received anti-H. treatment (n = 165)...

10.1097/ede.0b013e3181fe7e31 article EN Epidemiology 2010-11-11

ABSTRACT Background. Helicobacter pylori infection is usually acquired during childhood and a known risk factor for the development of gastric malignancies in adulthood. It has been reported that early age at first may determine neoplastic outcome adults. The purpose this study was to prevalence children residing areas with high (Pasto) low (Tumaco) cancer Colombia evaluate whether differences acquisition H. were present two populations. Materials Methods. sample based on census taken 1999....

10.1111/j.1083-4389.2004.00221.x article EN Helicobacter 2004-05-24

A new Helicobacter pylori infection affects growth velocity negatively, and clearing the produces a small significant rebound, but it is not known whether height weight in children are impacted over long term.

10.1097/inf.0b013e3182443fec article EN The Pediatric Infectious Disease Journal 2012-02-07

Introduction: In Colombia, information on cancer morbidity at the population level is limited. Incidence es­timates for most regions are based mortality data. To improve validity of these estimates, it necessary that other population-based registries, as well Cali, provide risk information. Objective: describe incidence and in municipality Pasto within 1998-2007 period. Methodos: The study belongs to rural urban areas Pasto. Collection, processing, systematization data were performed...

10.25100/cm.v43i4.1179 article EN Colombia medica 2012-12-29

BACKGROUND: A retrospective review of 239 patients with benign essential blepharospasm and Meige syndrome was performed in order to determine patients9 long term treatment preferences. METHODS: Of evaluated, 228 received local injections botulinum toxin, type A, into the eyelid facial musculature over 11 years. RESULTS: patients, 202 (72.1%) were still treated A. Eighteen (6.9%) no longer toxin sought other treatment. Five (2.2%) had apparent remission their disease after injection. Three...

10.1136/bjo.80.12.1073 article EN British Journal of Ophthalmology 1996-12-01

Population-based cancer registries provide vital information for planning, prevention and management. Information generated by the must be comprehensive, valid comparable. Because of their importance, regular quality assessments are recommended.The incidence data were assessed at four population-based in Colombia estimations.Data collected Bucaramanga, Cali, Pasto, Manizales included. Completeness was use graphs illustrating mortality ratios relation to survival. Validity evaluated...

10.1590/s0120-41572012000400009 article EN PubMed 2013-05-30

Gastric infection with Helicobacter pylori (H pylori), a strong risk factor for gastric cancer, is highly prevalent in children residing the Colombian Andes. We aimed to validate use of Entero-test culture and genotype H strains from asymptomatic children.

10.1097/mpg.0b013e318293e1e1 article EN Journal of Pediatric Gastroenterology and Nutrition 2013-03-30

Introduction. Population-based cancer registries provide vital information for planning, prevention and management. Information generated by the must be comprehensive, valid comparable. Because of their importance, regular quality assessments are recommended.Objective. The incidence data were assessed at four population-based in Colombia estimations.Material methods. Data collected Bucaramanga, Cali, Pasto, Manizales included. Completeness was use graphs illustrating mortality ratios...

10.7705/biomedica.v32i4.756 article EN publisher-specific-oa Biomédica 2012-06-14

Childhood leukemia (CL) is the most prevalent form of pediatric cancer on a global scale. However, there limited understanding dynamics CL incidence in South America, with specific knowledge gap Colombia. This study aimed to identify trends and analyze effects age, period, birth cohort risk this population. Information all newly diagnosed cases (in general by subtype) among residents aged 0–18 years living serving areas population-based registries Cali (2008–2017), Bucaramanga (2000–2017),...

10.1016/j.canep.2024.102548 article EN cc-by-nc Cancer Epidemiology 2024-02-29

El presente artículo analiza los límites constitucionales de la consulta popular, reconocida en el 104 Constitución ecuatoriana. Para ello, primero se examina importancia pero también identifican algunas sus desventajas, que nos llevan a cuestionar su eficacia para hacer realidad participación ciudadana. Posteriormente, justifica necesidad realizar una interpretación sistemática poder determinar alcance popular y analizan materiales este mecanismo participación, sobre base lectura integral...

10.18272/ulr.v8i2.2324 article ES cc-by-nc-sa USFQ Law Review 2021-10-26

BACKGROUND: A retrospective review of 239 patients with benign essential blepharospasm and Meige syndrome was performed in order to determine patients9 long term treatment preferences. METHODS: Of evaluated, 228 received local injections botulinum toxin, type A, into the eyelid facial musculature over 11 years. RESULTS: patients, 202 (72.1%) were still treated A. Eighteen (6.9%) no longer toxin sought other treatment. Five (2.2%) had apparent remission their disease after injection. Three...

10.1097/00041327-199712000-00062 article EN Journal of Neuro-Ophthalmology 1997-12-01
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