- Inflammatory mediators and NSAID effects
- Osteoarthritis Treatment and Mechanisms
- Foot and Ankle Surgery
- Natural product bioactivities and synthesis
- Morinda citrifolia extract uses
- NF-κB Signaling Pathways
- Genomics, phytochemicals, and oxidative stress
- Sirtuins and Resveratrol in Medicine
- Bee Products Chemical Analysis
- Orthopedic Surgery and Rehabilitation
- Chromatography in Natural Products
- Pharmacological Effects of Natural Compounds
- Diabetic Foot Ulcer Assessment and Management
Wenzhou Medical University
2019-2024
Ruian People's Hospital
2023
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2019
Random-pattern skin flaps have been widely used in the reconstruction of damaged tissues. Ischemia-reperfusion injury occurring distal regions flap is a common issue, which often leads to necrosis and restricts its clinical applications. Procyanidin B2 (PB2), naturally flavonoid large quantities various fruits, has demonstrated exhibit several significant pharmacological properties. However, effect PB2 on viability not clearly known. Here, using Western blot analysis, immunohistochemistry,...
Objective To assess the long‐term outcomes after percutaneous reduction (PR) and screw fixation versus plate via sinus tarsi approach (STA) for displaced intra‐articular calcaneal fractures (DIACF). Methods This retrospective study included a total of 150 patients (June 2008–August 2011), comprising 85 men 65 women (mean age, 38.4 years), who were assigned to PR group or STA group. The inclusion criteria DIACF (>2 mm) including Sanders type II III, closed fracture, unilateral no history...
Osteoarthritis (OA) is a common chronic disease characterized by progressive cartilage degeneration and secondary synovial inflammation. Bergamottin (Ber) an important natural derivative of the furanocoumarin compound, extracted from foods, such as pulp grapefruits pomelos. Ber exhibits several characteristicsthat are beneficial to human health, anti-inflammation, antioxidant, anti-cancer effects. However, role in treatment OA has not been elucidated date. Therefore, present study, vitro...
Osteoarthritis (OA) is a chronic and costly disease characterized by cartilaginous degradation inflammation in the joints. Syringic acid (SA), which extracted from Morus nigra Daphne gnidioides, possesses several health benefits, including antioxidant, antibacterial, anticancer activities. Previous research has demonstrated that SA can restrain immunocyte activation downregulate pro-inflammatory cytokine levels. Nevertheless, its role treatment of OA not been elucidated to date. In vitro...