Carlo Chiarla

ORCID: 0000-0001-9403-433X
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About
Contact & Profiles
Research Areas
  • Renal function and acid-base balance
  • Clinical Nutrition and Gastroenterology
  • Liver Disease Diagnosis and Treatment
  • Hemodynamic Monitoring and Therapy
  • Sepsis Diagnosis and Treatment
  • Lipoproteins and Cardiovascular Health
  • Respiratory Support and Mechanisms
  • Metabolomics and Mass Spectrometry Studies
  • Diet and metabolism studies
  • Electrolyte and hormonal disorders
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Metabolism and Genetic Disorders
  • Liver Disease and Transplantation
  • Cancer, Lipids, and Metabolism
  • Cardiac Arrest and Resuscitation
  • Cholinesterase and Neurodegenerative Diseases
  • Pancreatitis Pathology and Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Vascular Malformations and Hemangiomas
  • Prenatal Substance Exposure Effects
  • Thermoregulation and physiological responses
  • Trauma and Emergency Care Studies
  • Aldose Reductase and Taurine
  • Bone health and treatments

Università Cattolica del Sacro Cuore
2012-2022

Istituto di Analisi dei Sistemi ed Informatica Antonio Ruberti
2003-2019

National Research Council
2019

Agostino Gemelli University Polyclinic
2008-2018

Istituto di Sessuologia Clinica
1987-2015

Catholic University of America
1989-2010

Ospedale di Cattinara
1999

University of Maryland, Baltimore
1987-1992

Erasmus Hospital
1989

University of Maryland, College Park
1988

Serum amino acid (AA) profiles represent a valuable tool in the metabolic assessment of cancer patients; still, information on AA pattern head and neck (HNC) patients is insufficient. The aim study was to assess whether serum levels were associated with stage neoplastic disease prognosis primary HNC patients.Two hundred two included study. Thirty-one AAs derivatives measured through an ultraperformance liquid chromatography-mass spectrometry (UPLC-MS). association between concentrations...

10.1155/2020/2291759 article EN Disease Markers 2020-10-01

Quantitative relationships in CO2 transport and exchange processes were combined for use as the basic components of an original mathematical model calculation venoarterial blood concentration difference (v-aDCO2). This is calculated sum increment (CCO2) related to increase tension (delta P) from arterial venous value at constant O2 saturation CCO2/delta decrease S) S). The newly developed correlated well with experimental data which they derived (r2 = 0.94–0.99). results provided by compared...

10.1152/jappl.1993.74.2.959 article EN Journal of Applied Physiology 1993-02-01

Hypophosphatemia in critically ill and postoperative (p.o.) patients is a multifactorial event, also related to severity of illness. This study was conducted assess pathophysiologic correlates hypophosphatemia the simultaneous relationship with clinical events after hepatectomy. A total 333 measurements were obtained 59 patients: these performed preoperatively at p.o. days 1, 3, 7 all patients, subsequently, until recovery or death, only those complications. Measurements included plasma...

10.1097/00024382-200208000-00003 article EN Shock 2002-08-01

Although hypocholesterolemia in posttraumatic states is considered a generic expression of acute-phase response, relationship between severity and bad prognosis has also been found (1)(2)(3)(4)(5)(6). The issue still poorly understood complicated by the circumstance that plasma cholesterol affected simultaneously multiple factors whose impacts have never distinctly characterized. postoperative state after hepatectomy an interesting condition which most these may be present. We assessed...

10.1373/49.2.317 article EN Clinical Chemistry 2003-02-01

The effect of the infusion mixed amino acids with glucose and fat on metabolic rate (MR) in sepsis (S) nonseptic trauma (NS) was investigated. results demonstrated that diet-induced thermogenesis (specific dynamic action) controlled S NS 25% 18% MR variability, respectively (r2 = .25 .18, p less than .01 for both). Also, represented a quantitatively relevant portion total MR. There larger thermogenic respect to (22.3 vs. 5.7 cal/mg N, .01) concomitantly increased fat. suggest importance...

10.1097/00003246-198807000-00004 article EN Critical Care Medicine 1988-07-01

Objectives:Acute abdominal symptoms with CT scan evidence of intramural gas in bowel walls (pneumatosis cystoides intestinalis, PCI) and the portal venous blood (PBG) patients undergoing chemotherapy may represent a worrisome picture, suggestive necrosis. This picture remains major clinical clue reporting new cases help to share awareness experience on management. We describe patient acute PCI PBG under cetuximab, oxaliplatin, tegafur-uracil folinic acid for metastatic adenocarcinoma...

10.1185/03007990903566798 article EN Current Medical Research and Opinion 2010-01-18

Previous studies have shown that severe sepsis after major trauma results in the reprioritization of release hepatic acute-phase proteins (APP). They suggest competition for leucine nutritional utilization may be responsible. To test this hypothesis, a branched-chain enriched (46.6%) amino acid mixture (BCAA) was administered on prospective randomized basis with standard TPN therapy to 16 septic post-trauma patients. After diagnosed, (control-TPN or BCAA-TPN) given 12 days, until death...

10.1097/00005373-198808000-00006 article EN Journal of Trauma and Acute Care Surgery 1988-08-01

Background: Changes in plasma uric acid concentration (UA, μmol/L) postoperative and critical illness have pathophysiological clinical relevance may alter antioxidant capacity. This issue is poorly understood because UA simultaneously affected by multiple factors with impacts that never been definitively characterized.

10.1515/cclm.2007.502 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 2007-01-01

Metabolic and respiratory interactions were analyzed in a large group of septic patients (S) reference nonseptics (NS) during the iv administration glucose fat. In spite moderate increase CO 2 production (VCO ) observed fat S, VCO ‐sparing effect fat, with respect to equicaloric amounts glucose, was reconfirmed. The relevance therapeutic modulation parenteral nutrition, relative impact on abnormal patterns, emphasized by analyzing physiological relationships mechanisms responsible for work...

10.1177/0148607189013002141 article EN Journal of Parenteral and Enteral Nutrition 1989-03-01
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