A5102843875- Gut microbiota and health
- Substance Abuse Treatment and Outcomes
- Epigenetics and DNA Methylation
- Neuroendocrine regulation and behavior
- Opioid Use Disorder Treatment
- Clostridium difficile and Clostridium perfringens research
- HIV, Drug Use, Sexual Risk
- Genetic Syndromes and Imprinting
- Human-Animal Interaction Studies
- Oral microbiology and periodontitis research
- Veterinary Pharmacology and Anesthesia
- Stress Responses and Cortisol
- Human Resource Development and Performance Evaluation
- Traumatic Brain Injury Research
- Child and Adolescent Psychosocial and Emotional Development
- Maternal Mental Health During Pregnancy and Postpartum
- Colorectal Cancer Screening and Detection
- Adolescent and Pediatric Healthcare
- Helicobacter pylori-related gastroenterology studies
- Mental Health and Patient Involvement
- Early Childhood Education and Development
- Gastrointestinal motility and disorders
- Prenatal Screening and Diagnostics
Massachusetts General Hospital
2020-2024
Midwestern University
2024
Tennessee Technological University
2024
Tennessee State University
2024
Central Michigan University
2024
University of Madras
2024
Imperial College London
2012-2022
Brigham Young University
2019
Bryn Mawr College
2007-2011
In this manuscript, we investigate the "stones best left unturned" of sample storage and preparation their implications for next-generation sequencing infant faecal microbial communities by 16S ribosomal ribonucleic acid (rRNA) gene. We present a number experiments that potential effects often overlooked methodology factors, establishing "normal" degree variation expected between replica sequenced samples. Sources excess are then identified, as measured observation alpha diversity, taxonomic...
Background: Substance use disorder (SUD) treatment in general medical settings remains underutilized. We evaluated 5 years of a hospital-wide SUD initiative which included an inpatient addiction consult team (ACT), low-threshold Bridge Clinic, recovery coaches, and office-based (OBAT) nurses. Methods: Naturalistic registry study. calculated frequencies patient contacts, types substance diagnoses, medication initiation duration. Results: From 2014 to 2019, 7,036 unique patients were seen,...
The monoallelic expression of imprinted genes is controlled by epigenetic factors including DNA methylation and histone modifications. In mouse, the gene Gtl2 associated with two differentially methylated regions: IG-DMR, which serves as a gametic imprinting mark at paternal allele-specific inherited from sperm, Gtl2-DMR, acquires on allele after fertilization. timeframe during acquired secondary DMRs post-fertilization development relationship between have not been well established. order...
Abstract To address retention, attrition, and persistence issues, we have created an at-risk advising program for students who are deemed "academically at risk" in the College of Engineering. The designation includes on warning, probation, or returning from suspension. program, Eagle ExCEL- Engineers Connect, Engage, Learn, was collaboration with CoE administration professional advisors to help improve students' experiences chances success. Unfortunately, when engineering fail a class...
PICO Question In dogs with chronic pain, is acupuncture alone, compared to a placebo, more efficacious in alleviating pain and pain-related dysfunction? Clinical bottom line Category of research Treatment. Number type study designs reviewed Three controlled studies were critically appraised. Strength evidence Moderate. Outcomes reported Administration either fluoxetine or clomipramine adult reduces symptoms fear anxiety. Conclusion Both are effective reducing acral lick dermatitis tail...
Background: Treatment for substance use disorders (SUD) remains low in the United States. To better meet needs of people who alcohol and other drugs, threshold bridge clinics which offer treatment without barrier harm reduction services have gained prevalence. Bridge work to surmount barriers care by providing same day medication SUD eventually transitioning patients community-based providers. In this study, we examine outcomes among transitioned out a clinic. Methods: This is retrospective...
Peer recovery coaches (PRCs) are increasingly playing a role in helping patients with substance use disorders engage treatment. PRCs can support and motivate meeting their self-defined goals, engaging addiction treatment, navigating the health care system, overcoming barriers to recovery. This increases patient engagement is cost-effective. Little has been written about integrating settings. In this column, authors describe implementation of PRC program 23 serving 5,662 participants diverse...
Genomic imprinting results in parent of origin-specific monoallelic expression a subset mammalian genes. It has been suggested that the differentially methylated regions (DMRs) associated with many imprinted genes play role both marking parental alleles and controlling their expression. The mouse Gtl2 gene is solely expressed from maternal allele, two DMRs. IG-DMR located approximately 15 kb 5′ relative to transcriptional start site, between reciprocally Dlk1. Paternal allele-specific...
ABSTRACT Background The gastrointestinal (GI) microbiota has been linked to health consequences throughout life, from early life illnesses (e.g. sepsis and necrotising enterocolitis) lifelong chronic conditions such as obesity inflammatory bowel disease. It also observed that events in can lead shifts the microbiota, with some of these changes having documented persist into adulthood. A particularly extreme example a divergent GI occurs premature neonates, who display very different...