A5077426799- Medication Adherence and Compliance
- Pharmaceutical Practices and Patient Outcomes
- HIV/AIDS drug development and treatment
- Antibiotic Use and Resistance
- HIV/AIDS Research and Interventions
- Pneumocystis jirovecii pneumonia detection and treatment
- Sepsis Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Cancer Immunotherapy and Biomarkers
- Childhood Cancer Survivors' Quality of Life
- Cancer Diagnosis and Treatment
- Public Health and Environmental Issues
- Hepatocellular Carcinoma Treatment and Prognosis
- Infectious Diseases and Tuberculosis
- Immunodeficiency and Autoimmune Disorders
- Economic and Financial Impacts of Cancer
- Antibiotic Resistance in Bacteria
- Respiratory and Cough-Related Research
- Nosocomial Infections in ICU
- Tuberculosis Research and Epidemiology
- Multiple and Secondary Primary Cancers
- Long-Term Effects of COVID-19
- Bacterial Identification and Susceptibility Testing
- Antibiotics Pharmacokinetics and Efficacy
- Public Health in Brazil
Hospital Universitario Miguel Servet
2019-2024
<h3>Objectives</h3> The evidence for tocilizumab in the treatment of COVID-19 is contradictory, with some clinical trials showing benefits regard to progression mechanical ventilation (MV) and/or mortality. aim this study evaluate real practice effectiveness treating and identify prognostic factors patient outcomes. <h3>Methods</h3> This was an observational, retrospective patients treated between March 2020 February 2021 a tertiary hospital. Variables were demographics, comorbidities, vital...
evaluar la contribución del farmacéutico mediante el análisis de prescripción potencialmente inapropiada y conciliación tratamiento domiciliario en unidad pacientes crónicos complejos un hospital terciario. estudio observacional, prospectivo multidisciplinar los durante febrero 2019 - junio 2020. El equipo crónico complejo elaboró checklist con una selección fármacos no recomendados basado criterios STOPP/START, Beers PRISCUS susceptibles desprescripción según LESS-CHRON. aplicaba...
<h3>Background and importance</h3> The health crisis caused by the COVID-19 pandemic has impacted hospital pharmacy services (HPS). Our HPS, which belongs to region's referral hospital, had adapt quickly new circumstances ensure adequate pharmaceutical care (PC) drug distribution. <h3>Aim objectives</h3> To avoid interruption or lack of persistence chronic outpatient treatment during improve adherence discontinuation, as well reduce spread virus protect patients. <h3>Material methods</h3> A...
<h3>Background</h3> Olaparib and Niraparib are oral antineoplastics used for the maintenance treatment of high-grade ovarian cancer, relapsed, complete or partial response to platinum-based chemotherapy. is indicated patients with BRCA +mutation marketed in our country: independent mutation it compassionate use. <h3>Purpose</h3> Comparing safety profile Olaparib, everyday clinical practice a tertiary hospital. <h3>Material methods</h3> Descriptive, transversal, retrospective research all...
<h3>Background and importance</h3> The guidelines recommend anti-PD-1/PD-L1 immunotherapy as secondline treatment in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC), regardless of PD-L1 expression. <h3>Aim objectives</h3> To evaluate the effectiveness checkpoint inhibitors (ICI) (nivolumab, pembrolizumab atezolizumab) NSCLC. <h3>Material methods</h3> This was a descriptive, transversal, retrospective research all treated ICI for NSCLC between November 2013...
Objective The purpose of this study was to analyse the effectiveness and safety first-line treatment metastatic colorectal cancer (CRCm) in older patients treated a tertiary hospital. Material methods This an observational retrospective study, including aged 75 years or older, with CRCm, who received chemotherapy 2017. main variables studied were type treatment, Progression-Free Survival (PFS), Overall (OS), dose reductions, delays due adverse events. Results A total 59 (71.2% men) median...
Background Low-level viremias (LLVs) can be associated with age, suboptimal adherence, antiretroviral therapy (ART), and local epidemiology. The objective of the study was to analyze influence adherence ART on LLVs human immunodeficiency virus patients in a tertiary hospital. Methods A descriptive, multidisciplinary, observational, retrospective virus–naive who started between 2013 2018, have not undergone changes their ART, been treatment for at least 1 year conducted. following are...
In 2019, the European Committee for Study of Antibiotic Susceptibility modified categories antibiotic susceptibility tests to include term "susceptible with increased exposure". Following dissemination local protocols reflecting these modifications, aim our study was analyse whether prescribers have adapted them and clinical impact in cases inadequacy.Observational retrospective patients infection who received antipseudomonal antibiotics from January October 2021 a tertiary...
To analyze the modifications of antiretroviral therapy (ART) and their economic impact on daily clinical practice.Observational, retrospective study patients who started ART between 01/2017-12/2021 (follow-up until 12/2022). Variables collected: prescribed ART, duration, reason for change, treatment costs.A total 280 initiated therapy. The median durability 1st line was: 19.9 months in 2017 (95%CI 13.9-25.9), 12.2 2018 4.7-19.7), 27.4 2019 6.8-48.1) was not reached years 2020 2021 (p<0.001)....
<h3>Background</h3> The guidelines of antiretroviral therapy (ART) for the human immunodeficiency virus (HIV) recommend starting with all patients, regardless levels CD4 lymphocytes and symptomatology. <h3>Purpose</h3> Persistence: time a patient remains treatment frome beginning until interruption, reason. Aim this research: comparison between patients' persistence who different ART. <h3>Material methods</h3> Descriptive, transversal retrospective research that includes patients have...
Introducción: El tratamiento farmacológico del paciente oncopediátrico supone una dificultad para el equipo asistencial ya que muchos medicamentos registrados por la administración sanitaria no están indicados en población pediátrica, creándose un vacío terapéutico es cubierto a través de formulación magistral (FM). objetivo estudio analizar elaboración individualizados oncopediatría los últimos tres años Servicio Farmacia hospital tercer nivel. Métodos: Estudio descriptivo, observacional,...
<h3>Background and importance</h3> Cytomegalovirus (CMV) infection is an important cause of mortality, especially in haematological patients. Foscarnet has been used to treat ganciclovir resistant CMV infections. Only a few studies assessing safety effectiveness foscarnet have reported so far. <h3>Aim objectives</h3> To evaluate the treatment third level hospital. <h3>Material methods</h3> A retrospective observational study was conducted patients who received as for viraemia from January...
<h3>Background and importance</h3> Ceftaroline is approved for the treatment of complicated skin soft tissue infections (cSSSI), community acquired pneumonia (CAP). However, most specific aspect drug that it a beta-lactam with activity against methicillin resistant <i>Staphylococcus aureus</i> (MRSA). These characteristics mean large part its use in clinical practice off-label indications. <h3>Aim objectives</h3> To determine ceftaroline third level hospital, effectiveness safety....
<h3>Background and importance</h3> The increase in life expectancy, the higher incidence of cancer elderly patients lack clinical trials these makes it necessary to carry out studies that allow us know effect safety treatments. <h3>Aim objectives</h3> To analyse effectiveness firstline treatment metastatic colorectal (CRCm) treated a third level hospital. <h3>Material methods</h3> This was an observational retrospective study including aged ≥75 years with CRCm, who received chemotherapy...