Background: Sleep disturbance is common in intensive care patients. Aside from its unpleasantness, there a correlation with unit (ICU) syndrome/delirium. Reasons for sleep deprivation appear to be multifactorial, including the underlying illness, an acute superimposed disturbance, medications, and ICU environment itself. There are reasons believe that alterations of ‘biological clock’ might contribute. Melatonin secretion one reflection this internal sleep/wake mechanism. levels normally...

To investigate patients' psychological distress in relation to memory and stressful experiences the intensive care unit (ICU), identify early predictors for development of high levels acute post-traumatic stress disorder (PTSD)-related symptoms.A prospective cohort study was performed over 18 months two general ICUs, including 313 intubated mechanically ventilated adults admitted more than 24 h, 226 whom completed study. Patients were interviewed 5 days 2 post-ICU concerning their memories...

There is an evident need for improved management of elderly patients with trauma in order to avoid common and troublesome complications such as delirium. The aim this study was investigate whether implementation a multi-factorial program including intensified pre-hospital perioperative treatment care could reduce the incidence delirium hip fracture, cognitively intact at admission hospital. In addition, we explored factors that characterize who developed delirium.A prospective,...

Phosphate (Pi) sequestration by a lanthanum (La) exchanged clay mineral (La-Bentonite), which is extensively used in chemical lake restoration, was investigated on the molecular level using combination of (31)P and (139)La solid state NMR spectroscopy (SSNMR), extended X-ray absorption (EXAFS), powder diffraction (PXRD) sorption studies. SSNMR show that all Pi immobilized as rhabdophane (LaPO4·n H2O, n ≤ 3), further supported EXAFS. However, PXRD results were ambiguous with respect to...

The coordination chemistry of lead(II) in the oxygen donor solvents water, dimethylsulfoxide (dmso, Me(2)SO), N,N-dimethylformamide (dmf), N,N-dimethylacetamide (dma), N,N'-dimethylpropyleneurea (dmpu), and 1,1,3,3-tetramethylurea (tmu), as well sulfur solvent N,N-dimethylthioformamide (dmtf), has been investigated by extended X-ray absorption fine structure (EXAFS) and/or large angle scattering (LAXS) solution, single crystal diffraction EXAFS solid hydrates solvates. Lead(II) may either...

Lytic polysaccharide monooxygenases (LPMOs) are a recently discovered class of enzymes that employ copper-mediated, oxidative mechanism to cleave glycosidic bonds. The LPMO catalytic likely requires molecular oxygen first binds Cu(I), but the oxidation state in many reported structures is ambiguous, and changes active site required accommodate both states copper have not been fully elucidated. Here, diffraction data collection strategy minimizing deposited x-ray dose was used solve crystal...

The coordination chemistry of hydrated and solvated vanadium(III), oxovanadium(IV), dioxovanadium(V) ions in the oxygen-donor solvents water, dimethyl sulfoxide (DMSO), N,N'-dimethylpropyleneurea (DMPU) has been studied solution by extended X-ray absorption fine structure (EXAFS) large-angle scattering (LAXS) solid state single-crystal diffraction EXAFS. vanadium(III) ion a regular octahedral configuration with mean V-O bond distance 1.99 Å. In DMSO-solvated oxovanadium(IV) ions, vanadium...

Solid octaaqua(κ2O-perchlorato)thorium(IV) perchlorate hydrate, [Th(H2O)8(ClO4)](ClO4)3·H2O, 1, and aquaoxonium hexaaquatris(κO-trifluoromethanesulfonato)thorium(IV) trisaquahexakis(κO-trifluoromethanesulfonato)thorinate(IV), H5O2[Th(H2O)6(OSO2CF3)3][Th(H2O)3(OSO2CF3)6], 2, were crystallized from concentrated perchloric trifluoromethanesulfonic acid solutions, respectively. 1 adopts a severely distorted tricapped trigonal prismatic configuration with an additional oxygen the ion at longer...

The structures of the solvated copper(II) ion in water and nine organic oxygen donor solvents with similar electron-pair ability, but different space-demanding properties at coordination, have been studied by EXAFS. N,N'-Dimethylpropyleneurea N,N,N',N'-tetramethylurea are sufficiently space demanding coordination to make axial positions not accessible, resulting square-planar solvate complexes an intense green color. mean Cu-O bond distances these two 1.939(3) 1.935(3) Å, respectively. best...

The structures of the N,N′-dimethylpropyleneurea (dmpu) solvated lanthanoid(III) ions have been studied in dmpu solution (La−Nd, Sm−Lu) and solid iodide salts Sm, Gd−Lu) by extended X-ray absorption fine structure (EXAFS), single crystal diffraction (La, Pr, Nd, Gd, Tb, Er, Yb, Lu); EXAFS studies were performed on both K LIII edges. Because space-demanding properties upon coordination, metal often show coordination numbers lower than those found corresponding hydrates solvates oxygen donor...

Background: We have performed a prospective qualitative investigation of the ICU syndrome/delirium; main parts which recently been published. The aim present study was to explore relationship between syndrome/delirium and age, gender, length ventilator treatment, stay severity disease, as well factors related arterial oxygenation amount drugs used for sedation/analgesia. Methods: Nineteen mechanically ventilated patients who had stayed in more than 36 h were closely observed during their...

We performed a prospective study on 421 patients subjected to routine general‐, orthopaedic‐, urologic‐, gynecological and paediatric surgery estimate the current incidences of nausea vomiting during first 24 hours after surgery. The overall postoperative or were 17% 28%, respectively. Postoperative emetic symptoms not related age in adults. Women had more often than men ( P <0.01). In general, opiate premedication was frequently associated with benzodiazepines <0.01), but otherwise...

Journal Article Treatment of Coccidioidomycosis with Ketoconazole: Clinical and Laboratory Studies 18 Patients Get access John R. Graybill, Graybill Search for other works by this author on: Oxford Academic PubMed Google Scholar Doris Lundberg, Lundberg William Donovan, Donovan Hillel B. Levine, Levine Manuel Diaz Rodriguez, Rodriguez David J. Drotz Reviews Infectious Diseases, Volume 2, Issue 4, July 1980, Pages 661–673, https://doi.org/10.1093/clinids/2.4.661 Published: 01 1980

The structure around the absorbing atom in dicomplexes of CyMe₄-BTBP americium(<sc>iii</sc>) and europium(<sc>III</sc>) have been studied solvent used extraction.

Clonidine was administered intravenously in an attempt to limit sympatico‐adrenal activity and thereby reduce the incidence of arterial hypertension associated with coronary artery by‐pass graft surgery (CABG). Forty patients scheduled for CABG were assigned two groups. Twenty received clonidine 4μg kg ‐1 before surgery, 2 μg after cardiopulmonary 1 when skin sutured. The other 20 served as controls. All anesthetized fentanyl, droperidol, nitrous oxide alcuronium. During 5 min sternotomy,...

The present investigation attempted to determine if the previously reported depression of respiration by serotonergic agonists was a result peripheral or central nervous system drug effects. Systemic administration 5-hydroxytryptophan (5-HTP) pargyline-treated animals and 5-methoxy-N,N-di-methyltryptophan (5-MDMT) probably depress secondary penetration these drugs, since: 1) adult rats with biochemical evidence partial destruction neurons after neonatal intracisternal 5,7-dihydroxytryptamine...

Background: To assess and compare the feasibility stressful memories of light vs. heavy sedation during post‐operative mechanical ventilation. Methods: Randomized clinical trial in one general intensive care unit (ICU) a Swedish university hospital. Thirty‐six adults were randomly assigned to receive either [Motor Activity Assessment Scale (MAAS) 3–4] or (MAAS 1–2) with continuous i.v. infusion propofol invasive ventilation after oesophagectomy. The patients interviewed at ward 5 days...

Position isomerism is ubiquitous in atmospheric oxidation reactions. Therefore, we have compared surface-active oxygenated amphiphilic isomers (1- and 3-pentanol) at the aqueous surface with surface- chemically sensitive X-ray photoelectron spectroscopy (XPS), which reveals information about structure on a molecular level. The experimental data are complemented dynamics (MD) simulations. A concentration-dependent orientation solvation of amphiphiles observed. At bulk concentrations as low...