A5021302510- Acute Lymphoblastic Leukemia research
- Enhanced Recovery After Surgery
- Complement system in diseases
- Peripheral Neuropathies and Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Hemoglobinopathies and Related Disorders
- Cancer Cells and Metastasis
- Acute Myeloid Leukemia Research
- Immunodeficiency and Autoimmune Disorders
- Telemedicine and Telehealth Implementation
- Head and Neck Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Hepatitis C virus research
- Estrogen and related hormone effects
- Frailty in Older Adults
- Ear and Head Tumors
- Systemic Lupus Erythematosus Research
- Blood Coagulation and Thrombosis Mechanisms
- COVID-19 Impact on Reproduction
- Diet and metabolism studies
- Drug Transport and Resistance Mechanisms
- Heavy Metal Exposure and Toxicity
- Multiple and Secondary Primary Cancers
- Virology and Viral Diseases
- Barrier Structure and Function Studies
Heidelberg University
2016-2025
Goethe University Frankfurt
2025
University Hospital Heidelberg
2016-2025
University of California, San Francisco
2020-2024
University Hospital of Bern
2023
University of Bern
2023
University Children's Hospital Zurich
2023
University of Zurich
2023
University Medical Centre Mannheim
2016-2022
Hospices Civils de Lyon
2021
Background: Physicians are frequently unaware of patient preferences for end-of-life care. Identifying and exploring barriers to patient–physician communication about issues may help guide physicians their patients toward more effective discussions. Objective: To examine correlates associated outcomes with cardiopulmonary resuscitation prolonged mechanical ventilation. Design: Prospective cohort study. Setting: Five tertiary care hospitals. Patients: 1832 (85%) 2162 eligible completed...
The American Society for Apheresis (ASFA) Journal of Clinical (JCA) Special Issue Writing Committee is charged with reviewing, updating, and categorizing indications the evidence-based use therapeutic apheresis (TA) in human disease. In Ninth Edition, JCA has incorporated systematic review approaches grading evidence categorization to make recommendations on a wide variety diseases conditions. This edition largely maintained general layout concept fact sheet introduced Fourth Edition (2007)....
Current paediatric anaesthetic fasting guidelines have recommended conservative regimes for many years and not altered much in the last decades. Recent publications employed more liberal with no evidence of increased aspiration or regurgitation rates. In this first solely European Society Anaesthesiology Intensive Care (ESAIC) pre-operative guideline, we aim to present aggregated evidence-based summary recommendations assist clinicians, healthcare providers, patients parents. We identified...
Wilson's disease is a rare autosomal recessive genetic disorder that results in accumulation of copper the liver, brain, cornea and kidney. Therapeutic plasma exchange (TPE) has been used to remove provide bridge liver transplantation. We report here collective experiences through ASFA apheresis registry on disease.The multi-center study. Both prospective retrospective data, with latter involving data collection back January 2000 are entered registry. The includes patient demographics,...
The loss of breast cancer cell differentiation during metastatic progression leads to a down-regulation class 1 human leukocyte antigen (HLA) expression, which in turn hinders cytotoxic T lymphocytes from effectively preventing tumor proliferation. Consequently, one would expect that decreased HLA expression correlate with 5-year survival. However, estrogen receptor alpha (ESR1) is known be positively associated overall study aimed determine the levels HLA-A, HLA-B/C, and ESR1 assess their...
Background/Aim: Class 1 human leukocyte antigen (HLA) ensures that cytotoxic T lymphocytes (CTLs) attack tumor cells. As part of de-differentiation, the expression HLA on cell surface may decrease, which can facilitate growth. Therefore, reduced is generally negatively associated with overall survival (OS). The reverse true for programmed death protein (PD-1) and ligand (PD-L1). presence PD-1 PD-L1 cancer cells inhibits immune defense mechanisms against one would expect increased PD-1/PDL-1...
In order to evaluate the nature and frequency of adverse reactions associated with Therapeutic Apheresis (TA), database information from two large mobile apheresis services was analyzed. A total 17,940 procedures performed on 3,583 patients were studied using an Access Database. Seventy percent (12,558) a Fresenius AS104 blood cell separator 30% (5,382) COBE Spectra. The five most commonly treated diseases Guillain-Barre Syndrome (25%), thrombotic thrombocytopenic purpura (20%), myasthenia...
A young woman presented with a febrile illness in the third trimester of pregnancy. Laboratory investigation revealed severe acute hepatitis thrombocytopenia and coagulopathy. Liver injury progressed despite emergent caesarian section delivery healthy infant. Therefore, therapeutic plasma exchange (TPE) was performed on three consecutive days post‐partum for presumed diagnosis liver failure (ALF) associated pregnancy due to hemolysis, elevated enzymes, low platelets (HELLP) or fatty (AFLP)....
The serum protein designated 90K/Mac-2BP has been found at elevated concentrations in the sera of patients with various types cancer and viral infections. importance predicting response towards interferon-alpha treatment for hepatitis C virus (HCV) infection prompted us to utilize a new ELISA soluble human monitor this our HCV-positive patients. Seventy HCV-PCR anti-HCV antibody positive were analyzed their levels aspartate aminotransferase, alanine gamma-glutamyltransferase, cholinesterase,...
P Frykholm, N Disma, H Andersson, C Beck, L Bouvet, E Cercueil, Elliott, J Hofmann, R Isserman, A Klaucane, F Kuhn, M. de Queiroz Siqueira, D Rosen, Rudolph, A. R. Schmidt, Schmitz, Stocki, Sümpelmann, P. Stricker, M Thomas, Veyckemans, Afshari, Autoři překladu:, Harazim, Ťoukálková, V Valouchová, Štourač
Abstract Introduction: Physician supervision of apheresis contributes to safe and high‐quality patient care. Literature is limited regarding the requirements for hospital privileges physicians providing services. This report provides recommendations from American Society Apheresis (ASFA) this topic. Materials Methods: The ASFA Public Affairs Committee was charged by society's Board Directors (BOD) work collaboratively with other committees develop guidance pertaining in medicine. After...