Injection-induced necrosis is a rare but dreaded consequence of soft tissue augmentation with filler agents. It usually occurs as result injection directly into an artery, can also from compression or injury. We provide recommendations on the use hyaluronidase when vascular compromise suspected. Consensus were developed by thorough discussion and debate amongst authors at roundtable meeting Wednesday June 18, 2014 in Las Vegas, NV well significant ongoing written verbal communications months...

Enucleation is a commonly performed procedure. A multitude of intraorbital implants are available for use following enucleation. Each has advantages and disadvantages. This survey report represents the most comprehensive evaluation yet current trends in rehabilitation anophthalmic socket. The membership American Society Ophthalmic Plastic Reconstructive Surgeons (ASOPRS) was surveyed. Information requested regarding preferred implants, complications associated with each implant, some details...

Summary: Blowout fractures of the orbit are common sequelae to blunt facial trauma. Many aspects this injury have been studied, in particular, timing and indications for surgical intervention. Although diplopia is often an indication surgery presented patients as a potential postoperative complication, incidence after repair orbital blowout has not well studied. We retrospectively studied 54 who underwent fracture. A minimum 6 months follow-up was available all included study. total 47 (86%)...

DaxibotulinumtoxinA for Injection (DAXI) is a novel botulinum toxin type A formulation in clinical development. phase 2 dose-ranging study identified an optimal dose and demonstrated efficacy with median duration of 24 weeks.

Abstract This experimental study investigates the effect of mitomycin C (MMC) on sinus mucosal healing. MMC has an antiproliferative action fibroblasts. It is used in glaucoma surgery to prevent restenosis fistulas. Antrostomies were drilled rabbit maxillary sinuses. One side was as a control and other treated with at concentration 0.04, 0.4, or 1 mg/mL. Two animals from each group sacrificed 1, 2, 4, 12 weeks. The antrostomies 0.04‐mg/mL groups had closed by week; 0.4‐mg/mL 4 weeks,...

In 2022, the US experienced a significant increase in demand for minimally invasive aesthetic procedures, underscoring its rising acceptance amid an unregulated educational environment practitioners. The absence of standardized pathways and quality control medicine, primarily provided by nonacademic institutions, highlights critical need establishing standards to ensure practitioner competence patient safety.

BACKGROUND VYC-20L is a hyaluronic acid soft tissue filler with lidocaine designed to restore facial volume. OBJECTIVE Evaluate the safety and effectiveness of in patients chin retrusion. MATERIALS AND METHODS Adults retrusion were randomized (3:1) receive at study onset (treatment group) or 6 months later (control group). The primary end point was ≥1-point improvement on Allergan Chin Retrusion Scale (ACRS) from baseline Month 6. Safety assessments included injection site responses (ISRs)...

Endoscopic dacryocystorhinostomy (DCR) is a well-established alternative to external DCR for treatment of obstruction the lacrimal pathway and has success rate up 95% in primary cases. Despite benefits using an endoscopic approach, including enhanced intranasal access drainage system, there still exists significant failure rate, particularly revision procedures. As these failures are mainly due obstructive postoperative adhesions, intraoperative adjuncts that prevent or minimize scarring...

Microneedling and soft-tissue filler injections have been used independently to improve acne scarring. The effectiveness of a combined approach using microneedling followed by polymethylmethacrylate (PMMA)-collagen gel has not carefully studied.The goal this study was assess the safety alone versus injection PMMA-collagen for correction atrophic facial scars.We conducted multicenter, open-label, randomized, prospective on subjects with distensible scars in face determine whether is superior...

Background: Temple hollowing is characterized by the reduction of volume in temporal fossa, which can result a skeletonized look and contribute to an aged appearance. This study aimed evaluate safety effectiveness VYC-20L injectable gel for improvement temple hollowing. Methods: Adults with minimal, moderate, or severe hollows were randomized 2:1 receive no treatment. Participants followed 13 months assessments. Treatment was assessed blinded evaluating investigators using validated Allergan...

Abstract Background Masseter muscle prominence (MMP) is a benign condition characterized by wide, square, or trapezoidal lower facial shape, which may be considered undesirable. Objectives To evaluate onabotulinumtoxinA (onabotA) efficacy and safety for MMP treatment. Methods In phase 2b study, adults with investigator- participant-assessed bilateral grade 4/5 on the 5-grade Scale (MMPS) MMPS-Participant, respectively, were randomized 1:1:1 to receive single intramuscular injection of...

Abstract Background RelabotulinumtoxinA (relaBoNT-A; Relfydess, Galderma, Uppsala, Sweden) is a novel, ready-to-use liquid form of botulinum toxin A, created using PEARL technology to produce highly effective, complex-free formulation. Objectives Reporting subject-assessed effectiveness and satisfaction outcomes from the relaBoNT-A phase 3 READY-1 study. Methods Adults with moderate-to-severe glabellar lines were randomized 3:1 receive (50 U) or placebo in 6-month, double-blind, multicenter...

Glabellar contraction patterns were introduced to the scientific literature help guide glabellar neuromodulator injection algorithms. However, relationship between underlying musculature and its influence on these is unclear.

Background/Objective To evaluate the efficacy of a novel 0.25 cm2 monopolar radiofrequency (RF) treatment tip for aesthetic rejuvenation eyelids. Study Design/Materials and Methods This was prospective, multicenter trial in which eyelids 72 patients were treated. Patients underwent single session then followed on serial basis 6 months. Cutaneous anesthesia not required to perform treatments. Assessments made by treating physician, subjects, masked physician observers evaluating photographs...

Monopolar radiofrequency (RF) energy has been used to successfully accomplish noninvasive skin tightening of the face, abdomen, and extremities. Owing concerns about injury eye itself, monopolar RF treatment eyelids not feasible.The objective was evaluate safety a novel 0.25-cm(2)"shallow" tip for eyelid skin.This tripartite study that began with an animal model soft tissue effects temperature change at ocular surface. Findings were then extrapolated ex vivo evaluation human ultimately in...

Abstract Background Several laser technologies exist for improving rhytides, pigmentation, and skin texture. Recent advances in technology introduced a new wavelength, 2,790 nm, erbium:yttrium–scandium–galium–garnet (Er:YSGG) treatment of photoaging. nm Er:YSGG has water absorption coefficient between CO 2 Er:YAG both ablative fractional‐ablative capabilities. Objectives To evaluate the efficacy safety combining (confluent) modes Study Design/Materials Methods In this uncontrolled, open...

VYC-15L (Juvéderm Volbella XC) is a nonanimal crosslinked hyaluronic acid (HA) gel with lidocaine. To evaluate safety and effectiveness of repeat treatment administered 1 year after for lip perioral enhancement. In this prospective multicenter study, 124 subjects minimal, mild, or moderate fullness on the validated 5-point Allergan Lip Fullness Scale (LFS) who received initial/touch-up initial treatment. Effectiveness endpoints included LFS responder rates (≥1-point improvement from...

Background and Objectives Perfluorodecalin (PFD) has previously been shown to rapidly dissipate the opaque, white micro‐bubble layer formed after exposure of tattoos Q‐switched lasers [1]. The current pilot study was conducted qualitatively determine if use a transparent PFD‐infused silicone patch would result in more rapid clearance than conventional through‐air techniques. Materials Methods Black or dark blue were divided into two halves single‐site IRB‐approved with 17 subjects...

ABSTRACT Background Medical aesthetic procedures for facial rejuvenation with laser and energy‐based devices (EBDs) are rapidly increasing. The following cases highlight real‐life experience using a multi‐modality system various handpieces that combine intense pulsed light (IPL), hair removal (808 diode), high‐intensity focused ultrasound (HIFU), radiofrequency microneedling (RFM), thermal (RF) antiaging treatment. Laser RFM treatments may improve skin conditions by inducing cutaneous...

Micro-coring technology (MCT) removes cores of skin without formation scars, thereby tightening and reducing wrinkling. The purpose this study was to evaluate the safety efficacy MCT with dermal micro-coring device for treatment facial wrinkles.This prospective, multicenter clinical trial included fifty-one subjects who underwent treatments mid lower face. primary endpoint change in Lemperle Wrinkle Severity Scale. Secondary endpoints were Global Aesthetic Improvement Scale (GAIS),...

Abstract Background Recent research introduced the concept of “line convergence” as a guide for injectors to enhance precision and avoid complications when treating frontalis muscle with toxins. However, currently, no pre‐injection ultrasound scanning is employed increase reduce adverse events searching line convergence. Objective To explore feasibility practicality implementing into aesthetic neuromodulator treatments forehead. Methods The sample this study consisted n = 55 volunteers (42...

Abstract Background and Objectives Nonablative fractional lasers are well recognized for rejuvenating photoaged skin. We previously reported favorable outcomes with short follow‐up after the use of 1,440‐nm Nd:YAG laser energy used alone or in combination a 1,320‐nm to effect rejuvenation wrinkle reduction. now report longer data. Study Design/Materials Methods Nineteen Caucasian subjects (average age 47±8.4; range 33–62) exhibiting mild‐to‐moderate photoaging face neck were treated four...