A5048163373- Social and Educational Sciences
- Urban, Neighborhood, and Segregation Studies
- Urbanization and City Planning
- Protein Structure and Dynamics
- Migration, Aging, and Tourism Studies
- Enzyme Structure and Function
- School Choice and Performance
- Early Childhood Education and Development
- Housing, Finance, and Neoliberalism
- Health disparities and outcomes
- Rural development and sustainability
- RNA and protein synthesis mechanisms
- Biofuel production and bioconversion
- Housing Market and Economics
- Ubiquitin and proteasome pathways
- Global Educational Policies and Reforms
- Environmental Impact and Sustainability
- Homelessness and Social Issues
- Research in Social Sciences
- Urban Transport and Accessibility
- Intergenerational and Educational Inequality Studies
- Cancer-related Molecular Pathways
- Peatlands and Wetlands Ecology
- Education Systems and Policy
- Thermochemical Biomass Conversion Processes
Uppsala University
2015-2024
Stockholm University
2014-2023
Würth Elektronik (Germany)
2020
University of Gothenburg
2012-2020
Chalmers University of Technology
2005-2016
Göteborg Energi (Sweden)
2011-2016
Sweco (Sweden)
2008
Alfa Laval (Sweden)
2001
In recent years, structural changes to the school system, including introduction of independent schools, have increased choice alternatives in Sweden. Consequently, a large share today’s students attend other than one closest home. Since compulsory system is designed be free charge and offer same standard education everywhere, increasing choice– hypothetically—should not increase between-school variation grades. reality, however, grades has years. The aim this paper test whether variance can...
Planning for the housing situation of an ageing population is one challenges many countries. To increase our understanding needs population, a nationwide survey stratified on age and municipality type was conducted. Research questions referred to current plans. The aim investigate how preferences, location, and/or preferred changes with if they are market dependent. Results 10-year cohorts show that most marked change between cohort 75–84 years old oldest 85+. There gradual over time moves...
Viral proteins make extensive use of short peptide interaction motifs to hijack cellular host factors. However, most current large-scale methods do not identify this important class protein-protein interactions. Uncovering mediated interactions provides both a molecular understanding viral with their and the foundation for developing novel antiviral reagents. Here we describe discovery approach covering 23 coronavirus strains that high resolution information on direct virus-host We 269...
Viruses mimic host short linear motifs (SLiMs) to hijack and deregulate cellular functions. Studies of motif-mediated interactions therefore provide insight into virus-host dependencies, reveal targets for therapeutic intervention. Here, we describe the pan-viral discovery 1712 SLiM-based using a phage peptidome tiling intrinsically disordered protein regions 229 RNA viruses. We find mimicry SLiMs be ubiquitous viral strategy, novel proteins hijacked by viruses, identify pathways frequently...
This paper analyses whether a multi-scale representation of geographical context based on statistical aggregates computed for individualised neighbourhoods can lead to improved estimates neighbourhood effect. Our study group consists individuals born in 1980 that have lived Sweden since 1995 and we analyse the effect at age 15 educational outcome 30 controlling parental background. A new piece software, Equipop, was used compute socio-economic composition centred individual residential...
In 2009, Sweden experienced a wave of urban unrest concentrated in areas with large foreign-born populations. This episode was seen by many as reflecting trend towards increased ethnically based residential segregation, line scholarly literatures that correlate inequality and rising segregation increases or rebellion. this paper, we analyze the empirical connection between ethnic episodes Sweden. Unrest is measured number car burnings reported to police 2002 2009. We find positive...
In this paper, we use geo-coded, individual-level register data on four European countries to compute comparative measures of segregation that are independent existing geographical sub-divisions. The focus is non-European migrants, for whom aggregates egocentric neighbourhoods (with different population counts) used assess small-scale, medium-scale, and large-scale patterns. At the smallest scale level, corresponding with 200 persons, patterns over- under-representation strikingly similar....
In this paper, we analyse how a migrant population that is both expanding and changing in composition has affected the of Swedish neighbourhoods at different scales. The analysis based on geocoded individual-level register data for years 1990, 1997, 2005, 2012. This allows us to compute demographic range size from encompassing nearest 100 individuals 409,600 individuals. First, results confirm earlier findings migrants, especially those non-European countries, face high levels segregation...
Recognition motifs that mediate protein–protein interactions are usually embedded within longer intrinsically disordered regions. While binding interfaces involving the recognition motif in such well studied, less is known about role of regions flanking motifs. The interaction between transcriptional co-activators NCOA3 (ACTR) and CBP mediated by coupled folding two domains CID NCBD. Here, we used circular dichroism kinetics to directly quantify contribution adjacent its with Using N-...
Sweden is today an immigrant country with more than 14% foreign born. An increasing share of the immigrants comes from non-European countries. This implies that has been transformed ethnically homogenous into a large visible minority. In this paper we survey effect change on school segregation. Building Schelling's model for residential segregation, argue establishment minority triggered process segregation in some respects can be compared developments United States. order to test validity...
This article contributes both to the expanding literature on effect of school choice and focusing how measure conceptualize neighborhood effects. It uses a novel approach measurement geographical context analyze influences attitudes among Swedish parents. Data come from survey 3,749 families with children in upper primary school. Geographical is measured using multi-scalar contextual factors based socioeconomic indicators for individually defined, bespoke neighborhoods that incorporate 12...
Intrinsically disordered proteins (IDPs) are abundant in the proteome and involved key cellular functions. However, experimental data about binding kinetics of IDPs as a function different environmental conditions scarce. We have performed an extensive characterization ionic strength dependence interaction between molten globular nuclear co-activator domain (NCBD) CREB protein five ligands, including intrinsically activation p160 transcriptional co-activators (SRC1, TIF2, ACTR), p53...
The virus life cycle depends on host-virus protein-protein interactions, which often involve a disordered protein region binding to folded domain. Here, we used proteomic peptide phage display (ProP-PD) identify peptides from the intrinsically regions of human proteome that bind domains encoded by SARS-CoV-2 genome. Eleven proteins were found 281 proteins, and affinities 31 interactions involving eight determined (K
The aim of this study is to estimate the impact neighbourhoods on educational outcome for adolescents in Sweden. Using a multilevel statistical approach and PLACE database that consists census individuals 1990-2000 Sweden, paper explores different domains neighbourhood characteristics predict outcomes adolescents. Educational achievement year 2000 was measured three cohorts, geocoded their environments. It found related socioeconomic resources demographic stability are predictors individual...
One hypothesis is that, in Sweden, the elderly today are more willing to change residence accommodate for changing lifestyles and poorer health than earlier generations. If so, will their type of tenure from owner occupation tenant co-operative or rental housing, which includes services residents. The aim this study discover if people move apartments after leaving single-family housing that they own. Mobility patterns those born 1920s, 1930s 1940s analysed identify characteristics stayers...
Protein-protein interactions involving intrinsically disordered proteins are important for cellular function and common in all organisms. However, it is not clear how such emerge evolve on a molecular level. We performed phylogenetic reconstruction, resurrection biophysical characterization of two interacting protein domains, CID NCBD. appeared after the divergence protostomes deuterostomes 450-600 million years ago, while NCBD was present protostome/deuterostome ancestor. The most ancient...
Many intrinsically disordered proteins (IDPs) attain a well-defined structure in coupled folding and binding reaction with another protein. Such reactions may involve early to late formation of different native structural regions along the pathway. To obtain insights into transition state for reaction, we performed restrained molecular dynamics simulations using previously determined experimental Φb values interaction between two IDP domains: activation domain from p160 transcriptional...
Structural snapshots characterize six hundred million years of evolution intrinsically disordered proteins.