A5090752340- Catalytic C–H Functionalization Methods
- Asymmetric Hydrogenation and Catalysis
- Catalytic Alkyne Reactions
- Synthetic Organic Chemistry Methods
- Synthesis and Catalytic Reactions
- Asymmetric Synthesis and Catalysis
- CO2 Reduction Techniques and Catalysts
- Catalytic Cross-Coupling Reactions
- Carbon dioxide utilization in catalysis
- Oxidative Organic Chemistry Reactions
- Ionic liquids properties and applications
- Radical Photochemical Reactions
- Magnetism in coordination complexes
- Distributed systems and fault tolerance
- Advanced Database Systems and Queries
- Chemical Synthesis and Analysis
- Photonic and Optical Devices
- Organoboron and organosilicon chemistry
- Advancements in Battery Materials
- Cloud Computing and Resource Management
- Advanced Fiber Optic Sensors
- Metal complexes synthesis and properties
- Sulfur-Based Synthesis Techniques
- Ammonia Synthesis and Nitrogen Reduction
- Mechanical and Optical Resonators
Westlake University
2023-2024
Inner Mongolia Normal University
2024
Australian Regenerative Medicine Institute
2024
Monash University
2024
The University of Sydney
2014-2023
Southern University of Science and Technology
2020-2021
Dalian University
2017-2021
Dalian University of Technology
2017-2021
East China Normal University
2009-2020
The University of Tokyo
2020
Electroreduction of carbon dioxide with renewable electricity holds promise for achieving net-zero emissions. Single-site catalysts have been reported to catalyze carbon-carbon (C-C) coupling-the indispensable step more valuable multi-carbon (C2+) products-but were proven be transformed in situ metallic agglomerations under working conditions. Here, we report a stable single-site copper coordination polymer (Cu(OH)BTA) periodic neighboring coppers and it exhibits 1.5 times increase C2H4...
Abstract Herein, we develop a new approach to directly access architecturally complex polycyclic indolines from readily available indoles and bicyclo[1.1.0]butanes (BCBs) through formal cycloaddition promoted by commercially Lewis acids. The reaction proceeded stepwise pathway involving nucleophilic addition of BCBs followed an intramolecular Mannich form rigid indoline‐fused structures, which resemble indole alkaloids. This tolerated wide range BCBs, thereby allowing the one‐step...
An organo-photocatalytic sulfonylimination of alkenes was developed by employing readily available N-sulfonyl ketimines as bifunctional reagents. This transformation, featuring prominent functional group tolerance, provides a direct and atom-economic approach for the synthesis valuable β-amino sulfone derivatives single regioisomer. In addition to terminal alkenes, internal participate in this reaction with high diastereoselectivity. N-Sulfonyl aryl or alkyl substituents were found be...
Catalytic asymmetric cross-coupling of imines constitutes a particularly desirable method for the synthesis chiral vicinal diamines directly from readily available achiral precursors. The potential this lies in possibility utilizing variety as reacting partners. However, realization highly stereoselective two different proved to be formidable challenge. Herein we report an unprecedented catalytic reaction that tolerates ketimines and aldimines nucleophiles electrophiles, respectively....
New perspectives, in particular for the synthesis of isochromane derivatives (see scheme), are provided by title reaction. Excellent diastereoselectivites achieved this reaction which proceeds through a gold-catalyzed 1,3-acyloxy migration. In some cases exclusively Z isomer is detected.
Mobile: The title reaction affords diastereomerically pure 3,4-disubstituted pyrrolidin-2-ones, which are important structural motifs in natural products, good to high yields. Mechanistic investigations suggest the transformation proceeds through a tandem 1,3-acyloxy migration and subsequent 1,5-acyloxy migration. DCE=1,2-dichloroethane, IPr=1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene. Detailed facts of importance specialist readers published as "Supporting Information". Such documents...
Abstract Easily accessible propargylic esters are converted to the inverted alkynyl ketones in an oxidative gold‐catalyzed reaction. Gagosz’s catalyst combination with PhI(OAc) 2 is best system for this conversion and 18 examples yields up 80 % reported. The results indicate that triple bond product formed by elimination from a vinylgold intermediate. In formal sense new overall dehydrogenative Meyer–Schuster rearrangement.
Eleven different gold(I) complexes of new NHC ligands were prepared in excellent yield, demonstrating the versatility route to complexes. While influence electronically on synthesis catalysts was small, catalytic activities products differed significantly.
There is an established link between food promotions and children's purchase consumption. Children in developing countries may be more vulnerable to given the relative novelty of advertising these markets. This study aimed determine scope television children across Asia-Pacific inform policies restrict this marketing. Six sites were sampled, including from China, Indonesia, Malaysia South Korea. At each site, 192 h recorded (4 days, 16 h/day, three channels) May October 2012. Advertised...
Pharmaceuticals and biologically active natural products usually contain multiple stereocenters. The development of catalytic asymmetric reactions for the direct construction complex motifs containing three nonadjacent stereocenters is a particularly important formidable challenge. In this paper, we report an unprecedented method chiral amines with 1,3,5- or 1,3,4-stereocenters from readily available achiral racemic starting materials. reaction was made possible by highly efficient ammonium...
α-Aminophosphonic acids as an important class of bioisosteres α-amino demonstrate various biologically activities. We report here the development a highly enantioselective isomerization α-iminophosphonates enabled by extraordinarily efficient organocatalyst. This organocatalyst afforded total turnover number (TON) 20,000–1,000,000 for wide range α-alkyl iminophosphonates. Even at parts-per-million (ppm) loading, this catalyst achieved complete reaction in greater than 93% enantiomeric excess...
Neue Perspektiven, insbesondere für die Synthese von Isochroman-Derivaten (siehe Schema), eröffnet Titelreaktion, in der über eine Gold-katalysierte 1,3-Acyloxy-Wanderung wichtige C-C-Bindungsknüpfung mit guter bis ausgezeichneter Diastereoselektivität erreicht wird. In einigen Fällen wurde ausschließlich das Z-Isomer detektiert.
The palladium-catalyzed coupling of olefins and organohalides is a versatile approach for synthesizing complex molecules from simple starting materials. We have developed α-bromocarbonyl compounds with allylic alcohols the generation acyclic aryl-substituted dicarbonyl compounds. reaction proceeds via tandem olefin insertion an α-acyl radical followed by 1,2-aryl migration. In addition to providing preliminary evidence free mediated mechanism, we demonstrate unprecedented levels...
Demand for enterprise data warehouse solutions to support real-time Online Transaction Processing (OLTP) queries as well long-running Analytical (OLAP) workloads is growing. Greenplum database traditionally known an OLAP system with limited ability process OLTP workloads. In this paper, we augment into a hybrid serve both and The challenge address here achieve goal while maintaining the ACID properties minimal performance overhead. effort, identify engineering bottlenecks such...
Abstract Some readily available Boc‐protected 2‐(3‐methoxy‐1‐propynyl)anilines and nitrones in platinum‐catalyzed reactions deliver [1,2]oxazino[5,4‐ b ]indoles. Twelve examples with yields of 41–95% are reported. Different substituents like nitro, trifluoromethyl, fluoro, bromo, ester groups tolerated. With regard to the mechanism, this reaction probably combines an initial intramolecular cyclization/elimination vinylcarbenoid species a subsequent stepwise intermolecular [3+3] cycloaddition...
Mobiler Acylrest: Die Titelreaktion liefert diastereomerenreine 3,4-disubstituierte Pyrrolidin-2-one, die sehr wichtige Strukturmotive in Naturstoffen sind, guten bis ausgezeichneten Ausbeuten. Mechanistische Untersuchungen weisen darauf hin, dass Transformation über eine Tandem-1,3-Acyloxywanderung und nachfolgende 1,5-Acyloxywanderung verläuft.
Several new ruthenium complexes supported by the P,N-donor ligand 8-(diphenylphosphino)quinoline (DPPQ) were synthesized, including [RuCl2 (DPPQ)2 ] (1), [Ru(μ-Cl)(DPPQ)2 ]2 (BPh4 )2 (2), and [RuCl(DPPQ)2 Py](BF4 ) (3). Complex 2, with only 1 mol % loading, was found to be catalytically active for endo cycloisomerization of various terminal alkynols endo-cyclic enol ethers in moderate excellent yields. In particular, 7- 8-endo heterocyclization can achieved efficiently give seven-membered...
Electrochemical CO2 reduction reaction (CO2RR) that could utilise massive from industrial flue gas and the atmosphere provides a promising method to convert value-added fuels feedstocks powered by renewable electricity. Although significant progress has been made recently, carbonate formation in alkaline neutral electrolytes reduces longevity of device induces extra cost regeneration, thus limiting application CO2RR. In this review, we summarise recent efforts overcoming issue achieving high...
Abstract Leicht zugängliche Propargylester werden durch eine oxidative Gold‐katalysierte Reaktion in die invertierten Alkinylketone überführt. Der Gagosz‐Katalysator Kombination mit PhI(OAc) 2 erweist sich als das beste System für diese Umwandlung, und 18 Beispiele Ausbeuten bis zu 80 % beschrieben. Die Ergebnisse lassen darauf schließen, dass Dreifachbindung im Produkt Eliminierung aus einer Vinylgold‐Zwischenstufe entsteht. Formal ist neue dehydrierende Meyer‐Schuster‐Umlagerung.
Abstract An unprecedented copper‐catalyzed acylnitroso dearomatization reaction, which expands the traditional ene reaction and Diels–Alder to a new type of transformation, has been developed under aerobic oxidation. Intermolecular intra‐/intermolecular modes demonstrate an entirely different N ‐ or O ‐acylnitroso selectivity. Hence, we can utilize this as highly diastereoselective access series pyrroloindoline derivatives, are important structural motifs for natural‐product synthesis.
The [FeFe]-hydrogenase model, [(μ-bdt)Fe2(CO)6] (1, bdt = benzene-1,2-dithiolato), displays distinctive activity from its analogous complex, [(μ-edt)Fe2(CO)6] (2, edt ethane-1,2-dithiolato), for electrochemical CO2 reduction in acetonitrile with methanol or water as proton source. maximum turnover frequency of 195 s–1 estimated 1 is more than 4800 times higher that 2. influence reaction conditions on faradaic yield and product selectivity was investigated. Controlled potential electrolysis...