A5052526972- Bioinformatics and Genomic Networks
- Neuroendocrine regulation and behavior
- Animal Behavior and Reproduction
- Insect and Arachnid Ecology and Behavior
- Neurobiology and Insect Physiology Research
- Evolutionary Psychology and Human Behavior
- Attachment and Relationship Dynamics
- Evolutionary Game Theory and Cooperation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic Mapping and Diversity in Plants and Animals
- Chromosomal and Genetic Variations
- Gene expression and cancer classification
- Memory and Neural Mechanisms
- Plant and animal studies
- Genetic diversity and population structure
- Cell Image Analysis Techniques
- Infant Health and Development
- CRISPR and Genetic Engineering
- Stress Responses and Cortisol
- Machine Learning in Bioinformatics
- Biochemical Analysis and Sensing Techniques
- Avian ecology and behavior
- Philosophy and History of Science
- Aging and Gerontology Research
- Genomics and Phylogenetic Studies
Emory University
2008-2021
North Carolina State University
2014-2018
North Central State College
2014
Child Trends
2010
Cornell University
2004-2009
Oregon State University
2004
University of Kentucky
1998
Abstract Drosophila melanogaster males transfer seminal fluid proteins along with sperm during mating. Among these proteins, ACPs (Accessory gland proteins) from the male's accessory induce behavioral, physiological, and life span reduction in mated females mediate storage utilization. A previous evolutionary EST screen D. simulans identified partial cDNAs for 57 new candidate ACPs. Here we report annotation confirmation of corresponding Acp genes melanogaster. Of previously reported...
Abstract In Drosophila melanogaster, the genetic and molecular bases of post-mating changes in female's behavior physiology are poorly understood. However, DNA microarray studies have demonstrated that, shortly after mating, transcript abundance >1700 genes is altered reproductive tract as well other tissues. Many these elicited by sperm seminal fluid proteins (Acps) that males transfer to females. To further dissect transcript-level occur following we examined gene expression...
Egg and sperm have, understandably, been the “stars” of mammalian fertilization biology, particularly because artificial reproductive technologies allow for to occur outside female tract without other apparent contributions from either sex. Yet, recent research, including an exciting new paper, reveals unexpected important seminal plasma fertility. For example, proteins play critical roles in modulating physiology, a study mice demonstrates that effects some these on can even affect health...
In Drosophila melanogaster , accessory gland proteins (Acps) that a male transfers during mating affect his reproductive success by altering the female's behaviour and physiology. To test role of condition in expression Acps, we manipulated pre-adult environment examined adult males for relative transcript abundance nine post-copulatory traits Acps influence. Larval culture density had no effect on any measured trait. nutrient availability impacted number sperm transferred stored, male's...
Social interactions among conspecifics are a fundamental and adaptively significant component of the biology numerous species. Such give rise to group living as well many complex forms cooperation conflict that occur within animal groups. Although previous conceptual models have focused on ecological causes fitness consequences variation in social interactions, recent developments endocrinology, neuroscience, molecular genetics offer exciting opportunities develop more integrated research...
Medium spiny neurons (MSNs) in the nucleus accumbens have long been implicated neurobiological mechanisms that underlie numerous social and motivated behaviors as studied rodents such rats. Recently, prairie vole has emerged an important model animal for studying behaviors, particularly regarding monogamy because of its ability to form pair bonds. However, our knowledge, no study assessed intrinsic MSN electrophysiological properties or tested how these vary with strength bond between...
Objectives. Using a feminist social constructionist perspective, we illuminate how aging mothers and their caregiving daughters negotiate issues of connection, autonomy, conflict.
The prairie vole (Microtus ochrogaster) is a premier animal model for understanding the genetic and neurological basis of social behaviors. Unlike other biomedical models, voles display rich repertoire behaviors including formation long-term pair bonds biparental care. However, due to lack genomic resources this species, studies have been limited handful candidate genes. To provide substrate future development unique organism, we report construction characterization bacterial artificial...
The prairie vole (Microtus ochrogaster) is an emerging rodent model for investigating the genetics, evolution and molecular mechanisms of social behavior. Though a karyotype has been reported low-resolution comparative cytogenetic analyses have done in this species, other basic genetic resources such as linkage map, are lacking.Here we report construction genome-wide map vole. consists 406 markers that spaced on average every 7 Mb span estimated ~90% genome. sex length 1707 cM, which, like...
The genetic and environmental factors that contribute to pair bonding behaviour remain poorly understood. Prairie voles (Microtus ochrogaster) often, but not always, form stable bonds present an ideal model species for investigating the influence monogamy. Here, we assessed variation in partner preference, a measure of bonding, related social behaviours population laboratory-reared prairie under controlled conditions. We evaluated what extent these correlate with vasopressin 1a receptor...
Pair bonding with a reproductive partner is rare among mammals but an important feature of human social behavior. Decades research on monogamous prairie voles (Microtus ochrogaster), along comparative studies using the related non-bonding meadow vole (M. pennsylvanicus), have revealed many neural and molecular mechanisms necessary for pair-bond formation in that species. However, these largely focused just few neuromodulatory systems. To test hypothesis gene expression differences underlie...
Abstract Upon mating, Drosophila melanogaster females undergo numerous alterations in their behavior and reproductive physiology that are accompanied by small-magnitude transcript-level changes up to 1700 genes. Many of these postmating transcriptome the direct result sperm seminal fluid proteins (Acps) receive from mates. To begin determine if genetic background female's mate contributes previously described gene expression changes, we assessed whether interactions between genotypes two...
The prairie vole (Microtus ochrogaster) is an important model organism for the study of social behavior, yet our ability to correlate genes and behavior in this species has been limited due a lack genetic genomic resources. Here we report BAC-based targeted sequencing behaviorally-relevant flanking regions vole. A total 6.4 Mb non-redundant or haplotype-specific sequence assemblies were generated that span partial complete 21 as well additional 55 genes. Estimates nucleotide diversity from...
In most mammals, the X and Y chromosomes synapse recombine along a conserved region of homology known as pseudoautosomal (PAR). These homology-driven interactions are required for meiotic progression essential male fertility. Although PAR fulfills key functions in several exceptional species lack PAR-mediated sex chromosome associations at meiosis. Here, we leveraged natural variation programs present North American voles (Microtus) to investigate relationship between dynamics X/Y sequence...
Abstract Background Pair bonding with a reproductive partner is rare among mammals but an important feature of human social behavior. Decades research on monogamous prairie voles ( Microtus ochrogaster ), along comparative studies using the related non-bonding meadow vole M. pennsylvanicus have revealed many neural and molecular mechanisms necessary for pair-bond formation in that species. However, these largely focused just few neuromodulatory systems. To test hypothesis gene expression...