Mostafa Ghanem

ORCID: 0000-0001-9647-1357
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Microbial infections and disease research
  • Aquaculture disease management and microbiota
  • Herpesvirus Infections and Treatments
  • Plant Virus Research Studies
  • Animal Virus Infections Studies
  • Bacteriophages and microbial interactions
  • Salmonella and Campylobacter epidemiology
  • Molecular Biology Techniques and Applications
  • Viral gastroenteritis research and epidemiology
  • Genomics and Phylogenetic Studies
  • Child Nutrition and Water Access
  • Cannabis and Cannabinoid Research
  • Infectious Diseases and Tuberculosis
  • Viral Infections and Vectors
  • Mycobacterium research and diagnosis
  • Wound Healing and Treatments
  • Animal Nutrition and Physiology
  • Cancer Research and Treatments
  • Diabetic Foot Ulcer Assessment and Management
  • Mesenchymal stem cell research
  • Heme Oxygenase-1 and Carbon Monoxide
  • Coenzyme Q10 studies and effects
  • Tuberculosis Research and Epidemiology
  • Advancements in Battery Materials
  • Advanced battery technologies research

University of Maryland, College Park
2020-2024

Virginia–Maryland College of Veterinary Medicine
2020-2024

Alexandria University
2017-2022

The Ohio State University
2016-2021

International Trachoma Initiative
2020

eHealth Initiative
2020

Livestock farming provides a possible mechanism by which smallholder farmers can meet their household need for animal source foods (ASF), may reduce the risk of stunting. However, direct/indirect contacts with domestic animals increase colonization Campylobacter spp., has been associated Environmental Enteric Dysfunction (EED) and A cross-sectional study involving 102 randomly selected children between 12 16 months age was conducted in rural eastern Ethiopia to establish prevalence rates...

10.3389/fpubh.2020.615793 article EN cc-by Frontiers in Public Health 2021-01-21

Mycoplasma gallisepticum is the most virulent and economically important species for poultry worldwide. Currently, M. strain differentiation based on sequence analysis of 5 loci remains insufficient accurate outbreak investigation. Recently, whole-genome sequences (WGS) many human animal pathogens have been successfully used microbial investigations. However, massive data diverse properties different genes within bacterial genomes results in a lack standard reproducible methods comparisons...

10.1128/jcm.01145-17 article EN Journal of Clinical Microbiology 2017-10-25

Bilirubin has been recognized as a powerful cytoprotectant when used at physiologic doses and was recently shown to have immunomodulatory effects in islet allograft transplantation, conveying donor-specific tolerance murine model. We hypothesized that bilirubin, an antioxidant, acts suppress the innate immune response allografts through two mechanisms: 1) by suppressing graft release of damage-associated molecular patterns (DAMPs) inflammatory cytokines, 2) producing tolerogenic phenotype...

10.3727/096368916x692096 article EN cc-by-nc Cell Transplantation 2016-07-08

Abstract Background Drug resistant Mycobacterium tuberculosis prevention and care is a major challenge in Ethiopia. The World health organization has designated Ethiopia as one of the 30 high burden multi-drug (MDR-TB) countries. There limited information regarding genetic diversity transmission dynamics MDR-TB Objective To investigate molecular epidemiology strains using whole genome sequence (WGS) Amhara region. Methods Forty-five clinical isolates from region were collected between 2016...

10.1186/s12864-023-09502-2 article EN cc-by BMC Genomics 2023-07-17

Mycoplasma synoviae (MS) is a poultry pathogen with reported increased prevalence and virulence in recent years. MS strain identification essential for prevention, control efforts epidemiological outbreak investigations. Multiple multilocus based sequence typing schemes have been developed MS, yet the resolution of these could be limited investigation. The cost whole genome sequencing became close to that seven MLST targets; however, there no standardized method strains on sequences. In this...

10.1016/j.vetmic.2018.03.021 article EN cc-by-nc-nd Veterinary Microbiology 2018-03-21

Mycoplasma synoviae (MS) is a poultry pathogen that has had an increasing incidence and economic impact over the past few years. Strain identification necessary for outbreak investigation, infection source identification, facilitating prevention control as well eradication efforts. Currently, segment of variable lipoprotein hemagglutinin A (vlhA) gene (420 bp) only target used MS strain identification. major limitation this assay colonality typed samples can be inferred if their vlhA...

10.1637/11417-040516-reg article EN Avian Diseases 2016-10-17

Mycoplasma gallisepticum (MG) is the most pathogenic avian mycoplasma species. It affects commercial and noncommercial poultry wild birds. Current MG sequence typing methods rely on partial of one or more surface antigen genes. Multilocus (MLST), a widely used method for many human animal pathogens, relies conserved housekeeping Recently, MLST assays have been developed synoviae (MS) iowae. Additionally, whole genome-based core genome (cgMLST) assay has MS. However, cgMLST can be implemented...

10.1637/aviandiseases-d-19-00072 article ES Avian Diseases 2019-08-29

Abstract Identification of stable reference genes for normalization purposes is necessary obtaining reliable and accurate results reverse transcription quantitative polymerase chain reaction (RT-qPCR) analyses. To our knowledge, no gene(s) have been validated this purpose in Clostridium perfringens . In study, the expression profile ten candidate from three strains C. were assessed stability under various experimental conditions using geNorm qbase + These rankings then compared to...

10.1038/s41598-022-23804-7 article EN cc-by Scientific Reports 2022-11-13

The healing of an extraction socket leads to alveolar ridge resorption that can hinder future implant placement and further rehabilitation with special concerns in diabetes mellitus. Coenzyme Q10 (CoQ10) has been developed as a new material for augmentation. aim this study was investigate the effect CoQ10 hydrogel on bone regeneration after mandibular teeth Type II diabetic patients.This trial registered under number NCT05122299 included eighteen patients. first prepared characterized. After...

10.3390/jcm11113059 article EN Journal of Clinical Medicine 2022-05-29

Pasteurella multocida is one of the major causes mass mortalities in wild birds. Here, we report complete genome sequences two P. isolates from populations endangered seabird species, Indian yellow-nosed albatrosses (Thalassarche carteri) and northern rockhopper penguins (Eudyptes moseleyi).

10.1128/mra.01365-22 article EN Microbiology Resource Announcements 2023-03-27

Respiratory infections caused by Ornithobacterium rhinotrachealis (ORT) and Pasteurella multocida (PM) bacteria are significant threats to the poultry industry causing economic losses welfare issues. Due characterization difficulties underutilization of epidemiological tools, description spatio-temporal spread these diseases in field is limited. The objectives this retrospective observational cross-sectional study were (a) investigate existence space-time clusters (hotspots); (b) association...

10.3390/pathogens12081004 article EN cc-by Pathogens 2023-07-31

ABSTRACT Pasteurella multocida (PM) is a major bacterial pathogen that causes fowl cholera disease in both domestic poultry and wild birds. Here, we report the complete genome sequences of eight PM isolates representing all known lipopolysaccharide outer core loci, which are phenotypically expressed as 16 serotypes.

10.1128/mra.00604-24 article EN Microbiology Resource Announcements 2024-10-04

Malacoplasma iowae, previously known as "Mycoplasma iowae," is associated with embryo mortality, reduced hatchability, and leg abnormalities in turkeys, leading to considerable economic losses. Here, we report the complete annotated genome sequence of iowae type strain 695.

10.1128/mra.00490-22 article EN Microbiology Resource Announcements 2023-01-04

Ornithobacterium rhinotracheale has been associated with respiratory disease in poultry, particularly turkeys, leading to significant economic losses. However, O. is poorly studied, and a very limited number of complete genomes are available. Here, we report the genome sequences three strains, generated using Nanopore-Illumina hybrid assembly approach.

10.1128/mra.01059-22 article EN Microbiology Resource Announcements 2023-01-31

Abstract Identification of stable reference genes for normalization purposes is necessary obtaining reliable and accurate results reverse transcription quantitative polymerase chain reaction (RT-qPCR) analyses. To our knowledge, no gene(s) have been validated this purpose in Clostridium perfringens . In study, the expression profile ten candidate from three strains C. were assessed stability under various experimental conditions using geNorm qbase+. These rankings then compared to...

10.21203/rs.3.rs-1108435/v1 preprint EN cc-by Research Square (Research Square) 2021-12-06
Coming Soon ...